Description

Release form

Pills.

pharmachologic effect

Glutargin is a salt of arginine and glutamic acid.

In case of alcohol intoxication, it stimulates the utilization of alcohol in the monooxygenase system of the liver, prevents the inhibition of the key enzyme for the utilization of ethanol - alcohol dehydrogenase

accelerates the inactivation and elimination of toxic products of ethanol metabolism as a result of an increase in the formation and oxidation of succinic acid

reduces the depressing effect of alcohol on the central nervous system due to the neurotransmitter properties of excitatory glutamic acid.

Thanks to these properties, Glutargin exhibits antitoxic and sobering effects.

Glutargin also possesses hypoammoniemic and hepatoprotective properties due to the activation of ammonia detoxification processes in the body, antioxidant, antihypoxic and membrane stabilizing effects, and has a positive effect on energy supply in hepatocytes.

Glutargin does not have embryotoxic, gonadotoxic, mutagenic and teratogenic effects, does not cause allergic and immunotoxic reactions.

Indications

Prevention of intoxication and hepatotoxic effects of alcohol.

Treatment of acute alcohol intoxication and moderate severity, as well as in the complex therapy of post intoxication disorders after acute alcohol poisoning of severe degree.

Contraindications

- hypersensitivity to drug components

- children under 18 years old

- the period of pregnancy and lactation

Carefully

- febrile condition

- increased excitability

- severe violations of the filtration (nitrogen excretion) function of the kidneys (creatinine clearance 30 ml / min).

special instructions

When prescribing to patients with dysfunction of the endocrine glands, it should be borne in mind that the drug may slightly increase the secretion of insulin and growth hormones, which does not require correction of drug therapy in patients with diabetes mellitus and / or acromegaly

The effect of the drug on the ability to drive vehicles

The drug does not affect the ability to drive vehicles

Structure

Active ingredient: arginine glutamate (in terms of 100% substance) 1.0 g.

Excipient: microcrystalline cellulose (MCC 101) 0, 110 g, crospovidone 0.020 g, calcium stearate 0.010 g.

Method of administration and dosage

The drug is prescribed for adults inside, regardless of food intake.

For the prevention of intoxication and the hepatotoxic effect of alcohol, 2 tablets (2 g of arginine glutamate) are prescribed for 1-2 hours before drinking alcohol or 1 tablet (1 g of arginine glutamate) 1 hour before alcohol intake and 1 tablet (1 g of arginine glutamate) for 0 , 5 hours after drinking alcohol.

Side effects

Feelings of mild discomfort in the epigastric region and nausea immediately after using the drug, which go away on their own, can rarely be observed.

Overdose

Symptoms: nausea, vomiting, chest pain, epigastric discomfort, insomnia, transient short-term lowering of blood pressure, atrioventricular block, allergic reactions.

Treatment: symptomatic, if necessary, taking antihistamines, in severe cases - intravenous glucocorticosteroids.

Storage conditions

Store in original packaging, at a temperature not exceeding 25 C. Keep out of the reach of children.

Shelf life

2 years.

Active substance

Arginine glutamate

Name ENG

GLUTARGIN ALKOKLIN

Clinical and pharmacological group

Hypoammonaemic drug

ATX code

Arginine glutamate

Dosage

1g

Structure

Active ingredient: arginine glutamate (in terms of 100% substance) 1.0 g Auxiliary substance: microcrystalline cellulose (MCC 101) 0, 110 g, crospovidone 0.020 g, calcium stearate 0.010 g.

Indications

Prevention of intoxication and hepatotoxic effects of alcohol.

Treatment of acute alcohol intoxication and moderate severity, as well as in the complex therapy of post intoxication disorders after acute alcohol poisoning of severe degree.

Contraindications

Hypersensitivity to drug components

children under 18 years old

during pregnancy and lactation

Carefully

feverish condition

increased excitability

severe violations of the filtration (nitrogen excretion) function of the kidneys (creatinine clearance 30 ml / min).

INN / Active ingredient

arginine glutamate

Storage conditions and periods

At a temperature not exceeding 25 degrees, in the original packaging.

Expiration date: 5 years

Specifications