Griseofulvin | Griseofulvin tablets 125 mg, 20 pcs.

release form

Tablets



packaging 20 pcs

Indications

Mycosis of the skin, hair, nails: trichophytosis, favus, microsporia of the scalp, smooth skin, dermatomycosis of the beard and mustache, epidermophytosis of smooth skin, epidermophytosis of the feet, inguinal epidermophytosis, onychomycosis.

Contraindications

Hypersensitivity, porphyria, systemic lupus erythematosus, systemic lupus erythematosus syndrome, systemic blood diseases, leukopenia, acute and subacute diseases of the liver and kidneys with impaired function, liver failure, malignant neoplasms, cerebrovascular accidents, circulatory disorders, pregnancy, the period of breastfeeding, children's age (up to 2 years - effectiveness and safety have not been studied).

Special instructions

Treatment with Griseofulvin is carried out under the control of the morphological composition of the blood (1 time in 10-15 days).

Composition

1 tablet contains:

Active ingredient: griseofulvin 125 mg.

Dosage and administration

Inside, during or after a meal with vegetable oil. With microsporia, children are prescribed at the rate of 21–22 mg per 1 kg of the patient’s body weight per day, for adults - from 500 to 1000 mg (8 tablets per day). The drug is taken daily until the first negative test for mushrooms, then at the same dose every other day for 2 weeks and then 2 times a week for 2 weeks.

With trichophytosis (superficial and infiltrative-suppurative forms) and favus for children - at the rate of 18 mg / kg body weight according to the same scheme as with microsporia.

With onychomycosis, trichophytosis and favus of the scalp the daily dose for adults weighing up to 50 kg is 625 mg (5 tablets) The maximum daily dose is 1 g (8 tablets). The daily dose in children and adolescents is 16 mg / kg body weight.

In case of onychomycosis, the drug is prescribed daily for the first month, every other day for the second month, then 2 times a week in the same daily dose until the nails regrowth. The total duration of treatment is at least 8 months.

Side effects

From the side of the central nervous system: headache, dizziness, disorientation, unusual fatigue or weakness, insomnia, peripheral neuropathy, impaired coordination of movements, paresthesia of limbs, confusion.

From the gastrointestinal tract: nausea, vomiting, diarrhea, gastralgia, candidal stomatitis, hepatitis.

From the side of hematopoiesis: granulocytopenia, agranulocytosis, leukopenia.

Allergic reactions: urticaria, skin rash, itching, angioedema, photosensitivity, lupus-like syndrome, erythema multiforme exudative, Lyell's syndrome.

Drug Interactions

Enhances the action of ethanol. Reduces the activity of estrogen-containing oral contraceptives, indirect anticoagulants (due to the induction of microsomal liver enzymes). Barbiturates and primidone reduce antifungal activity.

Storage conditions

In a dry place, at a temperature not exceeding 20 РC.

Expiration

3 years 6 months

active substance

Griseofulvin

Terms leave through pharmacies

In retseptu

lekarstvennaja form

tablets

Russia, Russia, Russia biosynthesis