Grammidin children's tablets for resorption, No. 18

Grammidin children's tablets for resorption, No. 18; 'Symptomatic treatment of infectious and inflammatory diseases of the oral cavity and throat, accompanied by a sore throat and in the oral cavity: pharyngitis, tonsillitis, periodontitis, gingivitis, stomatitis.

Locally. It is used after meals, by absorption in the mouth, without chewing. Immediately after using the drug, you should refrain from eating and drinking for 1-2 hours.

Dosage for children from 4 to 12 years old: 1 tab. 4 times a day. The maximum daily dose is 4 tablets.

Dosage for children over 12 years old and adults: 2 tablets. (one after the other for 20-30 minutes) 4 times a day. The maximum daily dose is 8 tablets.

In the absence of a therapeutic effect within 7 days of taking the drug, it is recommended to consult a doctor.

White or off-white lozenges

1 tab.

gramicidin C (in the form of dihydrochloride) 1.5 mg

cetylpyridinium chloride (in the form of monohydrate) 1 mg

Excipients: colloidal silicon dioxide (aerosil 200) 5 mg, talc 60 mg, citric acid monohydrate 36 mg, aspartame 12 mg, raspberry flavor 3.6 mg, sorbitol (Neosorb) 1055.9 mg, magnesium stearate 25 mg.

-Hypersensitivity to the components of the drug;

-phenylketonuria (the drug contains aspartame);

- lactation period;

-Children up to 4 years old.

Pharmacodynamics

Combined drug for the symptomatic treatment of infectious and inflammatory diseases of the throat and oral cavity. The preparation contains the antimicrobial agent gramicidin C and the antiseptic agent cetylpyridinium chloride. The mechanism of action of gramicidin C is associated with an increase in the permeability of the cytoplasmic membrane of the microbial cell, which disrupts its stability and causes death. Gramicidin C has an antibacterial (bactericidal) effect against a wide range of gram-positive and gram-negative microorganisms. Cetylpyridinium chloride belongs to antiseptic agents, inhibits the growth and reproduction of causative agents of infectious diseases of the oral cavity. The drug has an antimicrobial effect, reduces inflammation, relieves discomfort in the throat, facilitates swallowing, causes hypersalivation when absorbed,which contributes to the mechanical cleansing of the oral cavity and pharynx from microorganisms.

Overdose

Symptoms: taking the drug in doses exceeding the recommended ones can cause disturbances in the gastrointestinal tract due to changes in the bacterial microflora: nausea, vomiting, diarrhea.

Treatment: you should stop taking the drug and consult a doctor.

Side effects

Allergic reactions to the components of the drug, gastrointestinal disorders (nausea, diarrhea) are possible.

Special conditions

GrammidinЃ for children should not be taken in the presence of open wounds in the oral cavity, since cetylpyridinium chloride slows down wound healing.

The effect of the drug on the ability to drive vehicles and mechanisms:

The drug does not affect the performance of potentially hazardous activities that require special attention and quick reactions (driving and other vehicles, working with moving mechanisms, the work of a dispatcher and operator, etc.).

Drug interactions

Currently, there are no cases of clinically significant interactions with other drugs.