Gramicidin C tab. 1.5 mg # 20 Renewal

Release form, composition and packaging

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Lozenges 1 tab.

gramicidin C 1.5 mg

20 pcs.

- polymer cans (1) - cardboard packs.

10 pieces.

- contour cell packages (2) - cardboard packs.

pharmachologic effect

An antibacterial agent, has a bacteriostatic (Streptococcus pneumoniae, meningococci, gonococci, pathogens of anaerobic infections) and in high concentrations, a bactericidal effect on Streptococcus spp.

and Staphylococcus spp.

Increases the permeability of the membrane of a microbial cell for inorganic cations due to the formation of a network of channels in the lipid structures of the membrane, which causes the development of osmotic instability of the cell.

Pharmacokinetics

Due to low systemic absorption, pharmacokinetic data are not available.

Indications for use

Water and fat solution - purulent wounds

- bedsores, ulcers

- burns

- osteomyelitis

- joint injury

- empyema

- phlegmon, carbuncle, boil (washing, irrigation of dressings and tampons).

Alcohol solution - pyoderma.

As part of combination therapy - infected eczema of the eyelids

- blepharitis

- meibomite (barley)

- scleritis, episcleritis

- iridocyclitis, iritis

- otitis externa.

Buccal tablets - infectious and inflammatory diseases of the mouth and throat: acute pharyngitis, tonsillitis, tonsillitis, periodontal disease, gingivitis, stomatitis.

Paste - local contraception

- burns

- wounds.

Contraindications for use

- hypersensitivity

- dermatoses (for external use)

- lactation period.

With care: pregnancy.

Dosage regimen

Locally.

To prepare an aqueous solution, a 2% solution is diluted 100-200 times with sterile distilled or ordinary drinking water.

To prepare a fat solution - a 2% solution is diluted with castor oil, fish oil, lanolin 25-30 times.

Used for washing, irrigation of dressings, tampons.

To prepare an alcohol solution, a 2% solution is diluted 100 times with 70% ethanol.

With pyoderma, the skin is lubricated with an alcohol solution 2-3 times a day.

Buccal tablets.

3 mg (2 tablets) one after the other (with an interval of 20-30 minutes) slowly dissolve in the mouth 4 times a day

per course - 15-30 mg.

Topical paste.

Apply a thin layer to the affected surface and cover with a gauze napkin.

The dressings are changed after 2-4 days.

As a contraceptive, 5-6 g is injected into the vagina with a special syringe.

Side effect

Allergic reactions, contact dermatitis, with parenteral administration - hemolysis, phlebitis.

Application during pregnancy and lactation

The drug is contraindicated for use during lactation (breastfeeding).

During pregnancy, appoint with caution.

Special instructions Water solution of gramicidin can be consumed within 3 days after preparation.

The introduction of solutions into a vein is not allowed - hemolysis and the development of phlebitis are possible.

Name ENG

GRAMICIDIN S

Clinical and pharmacological group

Antibiotic for topical use in ENT practice and dentistry

ATX code

Gramicidin

Dosage

1.5mg

Structure

Active ingredient: gramicidin C (calculated as active ingredient) 0.0015 g

Excipients: calcium stearate - 0.006 g

lactose (milk sugar) - 0.44169 g

sucrose (sugar) - 0.1482 g

food flavoring - 0.00198 g

sodium saccharinate (soluble saccharin) - 0.00063 g

INN / Active ingredient

gramicidin C

Storage conditions and periods

In a dry place, at a temperature not exceeding 25 degrees, in the original packaging.

Expiration date: 3 years

Specifications

Category

Sore throat

Scope of the drug

Ear, Throat, Nose

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

twenty

Scope of application

Virology

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

PFC update

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Antibiotic polypeptide structure

Anatomical and therapeutic characteristics

R02AB30 Gramicidin

Dosage form

Cheek pills

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

1.5 mg

Package weight, g

ten

Mode of application

:

Apply after meals, by slow absorption in the mouth, without chewing.

Within 1-2 hours after using the drug, you should refrain from eating and drinking.

Adults and children over 12 years old - 2 tablets (one after the other for 20-30 minutes) 4 times a day.

Children from 6 to 12 years old - 1-2 tablets 4 times a day (but not more than 7 tablets / day).

Children from 4 to 6 years old - 1 tablet 4 times a day.

The course of treatment is 5-6 days.

Application for more than 6 days is possible on the recommendation of a doctor.