Glycine tablets sublingual 100mg, No. 100

• Decreased mental performance;

• stressful situations - psychoemotional stress (during the exams, conflict situations, etc.);

• deviant forms of behavior of children and adolescents;

• various functional and organic diseases of the nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbances: neuroses, neurosis-like states and vegetative-vascular dystonia, the consequences of neuroinfections and traumatic brain injury; perinatal and other forms of encephalopathies (including alcoholic genesis);

• ischemic stroke.

Glycine is applied sublingually or buccal 100 mg (in tablets or as a powder after crushing the tablet).

For practically healthy children, adolescents and adults with psychoemotional stresses, memory loss, attention, mental performance, mental retardation with deviant forms of behavior, glycine is prescribed 1 tablet 2-3 times a day for 14-30 days.

With functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbance, children under three years of age are prescribed 05 tablets (50 mg) per dose 2-3 times a day for 7-14 days, then 50 mg once a day 7 -10 days. The daily dose is 100-150 mg; the course dose is 2000-2600 mg. For children over 3 years old and for adults, I prescribe 1 tablet 2-3 times a day, the course of treatment is 7-14 days. The course of treatment can be increased to 30 days, if necessary, the course is repeated after 30 days.

For sleep disorders, glycine is prescribed 20 minutes before bedtime or immediately before bedtime, 05-1 tablets (depending on age).

With ischemic stroke: during the first 3-6 hours from the development of a stroke, 1000 mg is prescribed buccal or sublingually with one teaspoon of water, then for 1-5 days, 1000 mg per day, then for the next 30 days, 1-2 tablets 3 times per day.

In narcology, glycine is used as a means of increasing mental performance and reducing psychoemotional stress during remission with symptoms of encephalopathy, organic lesions of the central and peripheral nervous system, 1 tablet 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.

For one tablet:

active substance: glycine 100 mg;

excipients : water-soluble methylcellulose 1 mg, magnesium stearate 1 mg.

• Individual hypersensitivity to the components of the drug.

Trade name of the drug

Glycine

International non-proprietary name

Glycine

Dosage form

sublingual tablets

Composition

For one tablet:

active substance: glycine 100 mg;

excipients : water-soluble methylcellulose 1 mg, magnesium stearate 1 mg.

Description

Tablets of white color with elements of marbling, flat-cylindrical shape with bevelling.

Pharmacotherapeutic group

Metabolic agent

ATX code

N06BX

Pharmacodynamics:

Glycine is a regulator of metabolism, normalizes and activates the processes of protective inhibition in the central nervous system, reduces psycho-emotional stress, increases mental performance. Glycine has glycine and GABAergic alpha1-adrenoceptor blocking antioxidant antitoxic effects; regulates the activity of glutamate (NMDA) receptors due to which the drug is able to:

- to reduce psycho-emotional stress, aggressiveness, conflict, to increase social adaptation;

- improve mood;

- facilitate falling asleep and normalize sleep;

- improve mental performance;

- to reduce vegetative-vascular disorders (including in menopause);

- to reduce the severity of cerebral disorders in ischemic stroke and traumatic brain injury;

- to reduce the toxic effect of alcohol and other drugs that inhibit the function of the central nervous system.

Pharmacokinetics:

Easily penetrates into most biological fluids and body tissues, incl. into the brain; metabolized to water and carbon dioxide, its accumulation in tissues does not occur.

Indications:

• Decreased mental performance;

• stressful situations - psychoemotional stress (during the exams, conflict situations, etc.);

• deviant forms of behavior of children and adolescents;

• various functional and organic diseases of the nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbances: neuroses, neurosis-like states and vegetative-vascular dystonia, the consequences of neuroinfections and traumatic brain injury; perinatal and other forms of encephalopathies (including alcoholic genesis);

• ischemic stroke.

Contraindications:

• Individual hypersensitivity to the components of the drug.

Method of administration and dosage:

Glycine is applied sublingually or buccal 100 mg (in tablets or as a powder after crushing the tablet).

For practically healthy children, adolescents and adults with psychoemotional stresses, memory loss, attention, mental performance, mental retardation with deviant forms of behavior, glycine is prescribed 1 tablet 2-3 times a day for 14-30 days.

With functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbance, children under three years of age are prescribed 05 tablets (50 mg) per dose 2-3 times a day for 7-14 days, then 50 mg once a day 7 -10 days. The daily dose is 100-150 mg; the course dose is 2000-2600 mg. For children over 3 years old and for adults, I prescribe 1 tablet 2-3 times a day, the course of treatment is 7-14 days. The course of treatment can be increased to 30 days, if necessary, the course is repeated after 30 days.

For sleep disorders, glycine is prescribed 20 minutes before bedtime or immediately before bedtime, 05-1 tablets (depending on age).

With ischemic stroke: during the first 3-6 hours from the development of a stroke, 1000 mg is prescribed buccal or sublingually with one teaspoon of water, then for 1-5 days, 1000 mg per day, then for the next 30 days, 1-2 tablets 3 times per day.

In narcology, glycine is used as a means of increasing mental performance and reducing psychoemotional stress during remission with symptoms of encephalopathy, organic lesions of the central and peripheral nervous system, 1 tablet 2-3 times a day for 14-30 days. If necessary, courses are repeated 4-6 times a year.

Side effects:

Allergic reactions are possible.

Interaction:

Reduces the severity of side effects of antipsychotics (neuroleptics) anxiolytics antidepressants hypnotics and anticonvulsants.

Release form / dosage:

Sublingual tablets 100 mg.

Packaging:

50 tablets in a blister strip packaging. 1 or 2 blisters in a cardboard box together with instructions for use.

Storage conditions:

In a dry, dark place at a temperature not exceeding 25 ? C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after the date indicated on the package.

Vacation conditions

Without recipe.