glucosamine sulfate | Don tablets 750 mg, 60 pcs.
Special Price
$37.83
Regular Price
$46.00
In stock
SKU
BID469933
Latin name
Dona
Dona
Latin name
Dona
Release form
Oblong oval-coated tablets, white-coated, 750 mg. On the cross section, two layers are visible - the outer white, the inner - white with a yellowish or brownish tint.
60 tablets in a plastic bottle with a snap-on lid, together with instructions for use, are placed in a cardboard box.
Pharmacological action
Pharmacodynamics
DONA has anti-inflammatory and analgesic effects, replenishes endogenous glucosamine deficiency, stimulates the synthesis of proteoglycans and hyaluronic acid, the synovial fluid and the cell penetrate the permeability cartilage. It promotes the fixation of sulfur during the synthesis of chondroitin sulfuric acid, facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.
Pharmacokinetics
Absorption in the gastrointestinal tract 90%, bioavailability 25%, half-life 70 hours.
Indications
Osteoarthrosis of the peripheral joints and spine, osteochondrosis.
Contraindications
Individual hypersensitivity to the active substance and other components of the drug, severe chronic renal failure. It is not recommended to prescribe the drug during pregnancy and lactation, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.
Use during pregnancy and lactation
It is not recommended to prescribe the drug during pregnancy and lactation due to the lack of scientific clinical data in this category of patients.
Special instructions
When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal failure, medical supervision is necessary.
Composition
One tablet contains:
active substance: glucosamine sodium sulfate chloride 942 mg (equivalent to glucosamine sulfate 750 mg and sodium chloride 192 mg)
excipients: microcrystalline cellulose 68 mg, povidone K 25 (polyvinylpyrrolidone K 25) 45 mg, croscarmellose sodium 20 mg, macrogol 6000 (polyethylene glycol 6000) 15 mg, magnesium stearate 8.50 mg, talc 1.50 mg
shell: methacrylic acid and methyl methacrylate copolymer [1: 1] (Eudragit L 12.5) 1 0 mg ground titanium dioxide 11.50 mg, talc 10.55 mg, methyl methacrylate, trimethylammonioethyl methacrylate chloride and ethyl acrylate copolymer [2: 0.2: 1] (Eudragit RL 30 D) 4.50 mg, triacetin (glycerol triacetate) 0.90 mg, macrogol 6000 (polyethylene glycol 6000) 0.55 mg.
Dosage and Administration
Inside.
1 tablet 750 mg is taken orally 2 times a day, preferably with meals, with a glass of water. Symptomatic effect occurs 2-3 weeks after the use of the drug. The minimum course of therapy is 4-6 weeks.
If necessary, repeat the treatment at intervals of 2 months. The duration and treatment regimen is prescribed by the attending physician.
Precautions for use:
Caution should be exercised in patients who are allergic to seafood (shrimp, shellfish). The drug contains 75.5 mg of sodium per tablet, which should be considered in patients who follow a controlled sodium diet. Use with caution in bronchial asthma and diabetes.
Side effects
Tolerance to the drug is good, in some cases possible: gastralgia, flatulence, nausea, diarrhea, constipation, headache, drowsiness, allergic reactions - erythema, urticaria, itching.
Drug Interactions
Compatible with non-steroidal anti-inflammatory drugs, paracetamol and glucocorticosteroids. Increases the absorption of tetracyclines, reduces semi-synthetic penicillins, chloramphenicol enhances the effect of coumarin anticoagulants.
Overdose
Overdose is unknown. Treatment: gastric lavage, symptomatic therapy.
Storage Conditions
Do not store above 25 C. Store in places out of reach of children.
Shelf life
3 years. Do not use after the expiration date printed on the package.
Deystvuyushtee substance
Glucosamine sulyfat
tablet dosage form of tablets
Possible product names
DONA 0.75 N60 TABLE P / O
DONA 750MG. No. 60 TAB. P / O
Dona tab p / p / o 750mg N60
DONA TAB. P.P.O. 750MG No. 60
Dona tab / o 0.75 No. 60
Rottafarm, Italy
Dona
Release form
Oblong oval-coated tablets, white-coated, 750 mg. On the cross section, two layers are visible - the outer white, the inner - white with a yellowish or brownish tint.
60 tablets in a plastic bottle with a snap-on lid, together with instructions for use, are placed in a cardboard box.
Pharmacological action
Pharmacodynamics
DONA has anti-inflammatory and analgesic effects, replenishes endogenous glucosamine deficiency, stimulates the synthesis of proteoglycans and hyaluronic acid, the synovial fluid and the cell penetrate the permeability cartilage. It promotes the fixation of sulfur during the synthesis of chondroitin sulfuric acid, facilitates the normal deposition of calcium in bone tissue, inhibits the development of degenerative processes in the joints, restores their function, reducing joint pain.
Pharmacokinetics
Absorption in the gastrointestinal tract 90%, bioavailability 25%, half-life 70 hours.
Indications
Osteoarthrosis of the peripheral joints and spine, osteochondrosis.
Contraindications
Individual hypersensitivity to the active substance and other components of the drug, severe chronic renal failure. It is not recommended to prescribe the drug during pregnancy and lactation, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.
Use during pregnancy and lactation
It is not recommended to prescribe the drug during pregnancy and lactation due to the lack of scientific clinical data in this category of patients.
Special instructions
When using the drug in patients with impaired glucose tolerance, with severe hepatic and renal failure, medical supervision is necessary.
Composition
One tablet contains:
active substance: glucosamine sodium sulfate chloride 942 mg (equivalent to glucosamine sulfate 750 mg and sodium chloride 192 mg)
excipients: microcrystalline cellulose 68 mg, povidone K 25 (polyvinylpyrrolidone K 25) 45 mg, croscarmellose sodium 20 mg, macrogol 6000 (polyethylene glycol 6000) 15 mg, magnesium stearate 8.50 mg, talc 1.50 mg
shell: methacrylic acid and methyl methacrylate copolymer [1: 1] (Eudragit L 12.5) 1 0 mg ground titanium dioxide 11.50 mg, talc 10.55 mg, methyl methacrylate, trimethylammonioethyl methacrylate chloride and ethyl acrylate copolymer [2: 0.2: 1] (Eudragit RL 30 D) 4.50 mg, triacetin (glycerol triacetate) 0.90 mg, macrogol 6000 (polyethylene glycol 6000) 0.55 mg.
Dosage and Administration
Inside.
1 tablet 750 mg is taken orally 2 times a day, preferably with meals, with a glass of water. Symptomatic effect occurs 2-3 weeks after the use of the drug. The minimum course of therapy is 4-6 weeks.
If necessary, repeat the treatment at intervals of 2 months. The duration and treatment regimen is prescribed by the attending physician.
Precautions for use:
Caution should be exercised in patients who are allergic to seafood (shrimp, shellfish). The drug contains 75.5 mg of sodium per tablet, which should be considered in patients who follow a controlled sodium diet. Use with caution in bronchial asthma and diabetes.
Side effects
Tolerance to the drug is good, in some cases possible: gastralgia, flatulence, nausea, diarrhea, constipation, headache, drowsiness, allergic reactions - erythema, urticaria, itching.
Drug Interactions
Compatible with non-steroidal anti-inflammatory drugs, paracetamol and glucocorticosteroids. Increases the absorption of tetracyclines, reduces semi-synthetic penicillins, chloramphenicol enhances the effect of coumarin anticoagulants.
Overdose
Overdose is unknown. Treatment: gastric lavage, symptomatic therapy.
Storage Conditions
Do not store above 25 C. Store in places out of reach of children.
Shelf life
3 years. Do not use after the expiration date printed on the package.
Deystvuyushtee substance
Glucosamine sulyfat
tablet dosage form of tablets
Possible product names
DONA 0.75 N60 TABLE P / O
DONA 750MG. No. 60 TAB. P / O
Dona tab p / p / o 750mg N60
DONA TAB. P.P.O. 750MG No. 60
Dona tab / o 0.75 No. 60
Rottafarm, Italy
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