Gentamicin sulfate 4% 100ml
DESCRIPTION
Gentamicin sulfate is an aminoglycoside antibiotic with bactericidal action. In appearance it is a colorless or slightly yellow transparent solution for injection.
COMPOSITION
The drug is a mixture of several antibiotics produced by Micromonospora purpurea and in 1 ml contains 40 mg of gentamicin sulfate and auxiliary components: sodium pyrosulfite, disodium salt of ethylenediamine tetraacetic acid and water for injection. In appearance it is a colorless or slightly yellow transparent solution for injection. The drug is packaged in 100 ml glass bottles.
PHARMACOLOGICAL PROPERTIES
Gentamicin has a broad spectrum of antimicrobial activity. It is active against most gram-negative and gram-positive microorganisms, including Proteus, Escherichia, Salmonella and Staphylococci. The antibiotic does not act on anaerobic bacteria, fungi, viruses and protozoa.
When administered intramuscularly, the drug penetrates well into many organs and tissues. The maximum concentration in the blood is reached 1 hour after administration. After a single injection, the therapeutic concentration of the antibiotic in the body is maintained for 8 to 12 hours after administration. When administered orally, the drug is practically not absorbed from the gastrointestinal tract and exerts its effect only in the intestine for 12 hours. With parenteral administration of gentamicin, the antibiotic is excreted unchanged from the body, mainly in the urine, and when administered orally, with feces.
INDICATIONS
Prescribed to cattle, horses, pigs, dogs and cats for the treatment of gastrointestinal, respiratory diseases, sepsis, peritonitis, meningitis, pyelonephritis and other diseases caused by antibiotic-sensitive microorganisms.
APPLICATION
A solution of gentamicin is administered intramuscularly or orally twice a day with an interval of 10 to 12 hours in the following doses:
Animal species Method of administration Dose, mg / kg for DV Dose, ml / 10kg of animal body weight Duration of use
Horses intramuscularly 2.5 0.6 3-5
Cattle and sheep intramuscularly 3 0.75 3-5
orally 8 2
Pigs intramuscularly 4 1.0 2-3
orally 8 1.5 3-5
Dogs and cats intramuscularly 2.5 0.6 3-7
The maximum volume of the drug for administration in one place to cattle and horses should not exceed 15 ml, pigs - 10 ml, sheep - 5 ml, dogs and cats - 2.5 ml.
SIDE EFFECTS
With increased individual sensitivity of the animal to the drug, the following are possible: refusal to feed, vomiting, impaired coordination of movements. In these cases, the use of the drug is discontinued, the animal is prescribed desensitizing therapy. In rare cases, the animal may develop edema at the injection site, which spontaneously resolves within 1 - 2 days and does not require treatment.
Slaughter of animals for meat is allowed no earlier than 21 days after the last use of the drug. The meat of animals that were forcedly killed before the expiration of the specified period can be used as feed for fur animals. Milk obtained from animals treated with gentamicin must not be used for food purposes during the treatment period and within 72 hours after the last administration of the drug.
CONTRAINDICATIONS
Increased individual sensitivity of animals to gentamicin sulfate. The drug should not be administered with antibiotics of the penicillin, streptomycin, kanamycin and neomycin group, and also mixed with other drugs in the same syringe. It is not allowed to use the drug in severe renal impairment.
STORAGE
Store in closed manufacturer's packaging, in a dry, dark place, out of reach of children and animals, separately from food and feed at temperatures from + 5 В° C to + 25 В° C. Shelf life, subject to storage conditions, is 2 years from the date of production.
PACKING
The drug is packaged in 100 ml glass bottles.
Specifications
KolVUP
70
Manufacturer
BiAgro
Temperature regime
from +5 to +25
Teaser
for the treatment of gastrointestinal, respiratory diseases, sepsis, peritonitis, meningitis, pyelonephritis and other diseases caused by antibiotic-sensitive microorganisms