Gaviscon Double Action Mint Chewable Tablets, No. 12

Treating symptoms of gastroesophageal reflux such as:

• sour belching

• heartburn,

• dyspepsia (indigestion, feeling of heaviness in the stomach) that occurs after eating, in patients with high acidity of gastric juice or during pregnancy.

Inside, after thorough chewing.

Adults and children over 12 years old: 2-4 tablets after meals and before bedtime (up to 4 times a day).

The maximum daily dose is 16 tablets. For elderly patients, dose changes are not required.

One chewable tablet contains:

active ingredients: sodium alginate 250 mg, sodium bicarbonate 106.5 mg, calcium carbonate 187.5 mg;

excipients: mannitol 598.799 mg, macrogol-20000 30 mg, copovidone 33.75 mg, acesulfame potassium 5.863 mg, aspartame 5.863 mg, dye azorubin (11012) 0.375 mg, mint flavor 18.75 mg, xylitol (DC) 100 mg, magnesium stearate 6.75-12.6 mg.

Х hypersensitivity to any component of the drug;

Х phenylketonuria (see the section 'Special instructions');

Х renal failure of moderate and severe severity;

Х children under 12 years of age.

Carefully:

If you have the following diseases or conditions, you should consult your doctor before using the drug: hypercalcemia, nephrocalcinosis and urolithiasis with the formation of calcium oxalate stones; congestive heart failure; renal failure of mild severity.

Application during pregnancy and breastfeeding:

Clinical studies involving more than 500 pregnant women and the amount of data obtained in the post-registration period did not show congenital, fetal and neonatal toxicity of the active substances. GavisconЃ Dual Action can be used during pregnancy if clinically necessary and after consultation with a physician. Duration of use during pregnancy - no more than 7 days. GavisconЃ Dual Action can be used during breastfeeding.

Pharmacology.

This drug is a combination of alginate and antacids (calcium carbonate and sodium bicarbonate). When taken orally, the active ingredients of GavisconЃ Double Action react quickly with the acidic contents of the stomach. This forms an alginate gel with a pH value close to neutral. The gel forms a protective barrier on the surface of the stomach contents, preventing gastroesophageal reflux (reflux of stomach contents into the esophagus). In severe cases of reflux (regurgitation), the gel is thrown into the esophagus ahead of the rest of the gastric contents, where it reduces irritation of the esophageal mucosa. Calcium carbonate quickly neutralizes gastric acid hydrochloric acid, relieving heartburn and indigestion.This effect is enhanced by the presence of sodium bicarbonate in the preparation, which also has a neutralizing effect. The total acid-neutralizing activity of the drug in a minimum dose of 2 tablets is approximately 10 mEq.

Pharmacokinetics:

The drug has no systemic bioavailability (not absorbed).

Special instructions:

In a dose of two tablets, the sodium content is 110.75 mg (4.82 mmol). This should be taken into account when it is necessary to adhere to a diet with limited salt content, for example, with congestive heart failure and renal failure of mild severity. Each dose of two tablets contains 150 mg (3.75 mmol) of calcium. Therefore, care should be taken when treating patients with hypercalcemia, nephrocalcinosis and urolithiasis with the formation of calcium oxalate stones. Due to the aspartame content, this drug should not be used in patients with phenylketonuria. GavisconЃ Dual Action contains antacids that can mask the symptoms of serious gastrointestinal diseases. A decrease in the effectiveness of the drug in patients with low acidity of gastric juice is possible.In patients with gastroenteritis or suspected renal failure, there is an increased risk of hypernatremia with the drug. You should not use the drug for a long time, if symptoms persist after 7 days of taking the drug, you should consult a doctor to review therapy. The drug does not affect the ability to drive vehicles and mechanisms, as well as to engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.it is necessary to consult a doctor to review therapy. The drug does not affect the ability to drive vehicles and mechanisms, as well as to engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.it is necessary to consult a doctor to review therapy. The drug does not affect the ability to drive vehicles and mechanisms, as well as to engage in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Side effect:

Immune system disorders: of unknown frequency - anaphylactic and anaphylactoid reactions, hypersensitivity reactions (urticaria).

Disturbances from the respiratory system, chest and mediastinal organs: of unknown frequency - respiratory effects (bronchospasm).

If any of the side effects indicated in the instructions are aggravated, or you notice other side effects that are not listed in the instructions, inform your doctor.

Overdose:

Symptoms: Abdominal bloating may occur. Treatment: symptomatic.

Interaction with other medicinal products:

Since calcium carbonate, which is part of the drug, exhibits antacid activity, at least 2 hours should elapse between taking GavisconЃ Double Action and other drugs, especially when taken simultaneously with H2-histamine receptor blockers, antibiotics from the tetracycline group, digoxin, fluoroquinolone, iron salts, ketoconazole, neuroleptics, thyroid hormones, levothyroxine sodium, penicillamine, beta-blockers (atenolol, metoprolol, propranolol), glucocorticosteroids, chloroquine, bisphosphonates and estramustin.