Frontline Combo S for dogs weighing 2-10 kg (1 pipette) 0.67 ml

DESCRIPTION

Frontline Combo S is an insect-acaricidal preparation for combating fleas (eggs, larvae, sexually mature forms) and ticks for dogs weighing from 2 to 10 kg. Dosage form: solution for external use.

COMPOSITION

The drug contains fipronil - 9.8% and S-methoprene - 8.8% as active ingredients, and polyvidone and polysorbate as auxiliary substances. It is a colorless transparent liquid with a weak specific odor.

PHARMACOLOGICAL PROPERTIES

It has a pronounced contact insect-acaricidal effect, is active against the preimaginal and imaginal phases of development of lice, fleas, lice and ticks (ixodid, cheilitella) parasitizing on dogs.

The mechanism of action of fipronil is to block the GABA-dependent (GABA-gamma-aminobutyric acid) receptors of parasites, impairing the transmission of nerve impulses, which leads to paralysis and death of ectoparasites.

S-methoprene inhibits the juvenile hormone that promotes the formation of chitin, thereby disrupting the development of fleas at the egg and larval stage.

When applied to the skin, the drug is not absorbed, but gradually, within 24 hours, is distributed over the surface of the body and, being reserved in the sebaceous glands, has a long insect-acaricidal effect in the places of localization of ectoparasites.

Frontline Combo, in terms of the degree of impact on the body, belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007.76), in recommended doses, it does not have skin resorptive, sensitizing, embryotoxic, teratogenic and mutagenic effects. Causes minor irritation in eye contact.

INDICATIONS

Assign to dogs weighing from 2 to 10 kg to combat fleas, lice, lice and ticks (ixodid, cheilitella).

APPLICATION

Frontline Combo is applied externally by topical (Spot On) application to the skin. Before processing, the tip of the pipette is broken off, the animal's hair is pushed apart in the back area (between the shoulder blades) and, pressing the pipette, the preparation is applied to the skin at one or several points.

The protective effect of the drug against ixodid ticks in dogs lasts at least 1 month, against adult insects up to 3 months, from the preimaginal phases of insect development to 8 months.

In case of severe damage to the animal by lice, fleas, lice, it is recommended to process it once a month. If the animal is washed more than 2 times a month, it is recommended to reduce the interval between treatments to 3 weeks. It is not recommended to wash animals within 48 hours after treatment with Frontline Combo, as well as to use other insecticidal and acaricidal agents.

SPECIAL INSTRUCTIONS

With increased individual sensitivity to the components of the drug and the appearance of signs of allergic reactions, the treatment is stopped, the drug is washed off with water, and antihistamines are given inside.

CONTRAINDICATIONS

Increased individual sensitivity to drug components. Sick and recovering animals, as well as puppies younger than 8 weeks of age, cannot be processed.

SIDE EFFECTS

Allergic reactions are possible in hypersensitive animals.

PRECAUTIONS

During the procedure with Front Line Combo, you should follow the rules of personal hygiene and safety measures provided for working with medicines for animals. While working with the medicinal product, it is not allowed to drink, smoke, eat. At the end of work, hands should be washed with warm water and soap. It is forbidden to use empty pipettes from under the drug for domestic purposes, they must be disposed of with household waste.

FIRST AID MEASURES

In case of accidental contact with Front Line Combo on the skin or mucous membranes, it should be washed off with a stream of water.

STORAGE

In the manufacturer's packaging, in a dry, dark place, out of the reach of children and animals, at temperatures from 0 В° C to 25 В° C. The shelf life is 3 years.

PACKING

The drug is released packaged in 0.67 ml in polyethylene pipette tubes.

Specifications

Product subcategory

Drops from fleas and ticks

KolVUP

five

Manufacturer

Merial

Temperature regime

from 0 to +30

Teaser

insect-acaricidal preparation for combating fleas (eggs, larvae, sexually mature forms) and ticks for dogs weighing from 2 to 10 kg