Folacin 5 mg tab # 30

Special Price $8.82 Regular Price $16.00
In stock
SKU
OTC1020514
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Category

Vitamin and mineral complexes

Scope of the drug

Vitamins

Release form

Tablet

Manufacturer country

Croatia

Package quantity, pcs

thirty

Description

Release form, composition and packaging Tablets are round, flat-cylindrical, yellow in color with slight marbling, the presence of orange blotches is allowed, with a chamfer and a line on one side, odorless.

1 tab.

folic acid

5 mg

lactose monohydrate - 133.92 mg, microcrystalline cellulose - 50 mg, magnesium stearate - 1 mg, povidone - 5.04 mg, crospovidone - 5.04 mg.

10 pieces.

- blisters (1) - packs of cardboard. 10 pcs.

- blisters (2) - cardboard packs. 10 pcs.

- blisters (3) - packs of cardboard. Pharmacological action Vitamin of group B. Folic acid in the body is converted into tetrahydrofolic acid, as a coenzyme, participating in various metabolic processes, and necessary for the normal maturation of megaloblasts and the formation of normoblasts.

With a deficiency of folic acid, a megaloblastic type of hematopoiesis develops.

The drug stimulates erythropoiesis, participates in the synthesis of amino acids (including methionine, serine, glycine), nucleic acids, purines, pyrimidines, in the exchange of choline, histidine.

During pregnancy, it performs a protective function in relation to the action of teratogenic and fetal-damaging factors.

Contributes to the normal maturation and functioning of the placenta.

Pharmacokinetics.

Suction.

After ingestion, folic acid, combining in the stomach with the internal Castle factor (a specific glycoprotein), is well and completely absorbed from the gastrointestinal tract.

Cmax in the blood is reached after 30-60 minutes.

Distribution and metabolism

It binds almost completely to plasma proteins.

Deposited and metabolized in the liver with the formation of tetrahydrofolic acid (in the presence of ascorbic acid under the action of the enzyme dihydrofolate reductase).

Penetrates the BBB and placental barrier, excreted in breast milk.

Withdrawal

It is excreted by the kidneys both unchanged (if the dose taken significantly exceeds the daily requirement) and in the form of metabolites.

It is excreted using hemodialysis.

5 mg taken orally folic acid is excreted from the body after 5 hours. Indications for use - treatment and prevention of folic acid deficiency against the background of unbalanced or malnutrition

- treatment and prevention of anemia in the presence of folic acid deficiency (macrocytic hyperchromic anemia, anemia and leukopenia caused by drugs and ionizing radiation, megaloblastic anemia, post-resection anemia, sideroblastic anemia in elderly patients, anemias associated with diseases of the small intestine, sprue and syndrome malabsorption)

- treatment and prevention of anemia during pregnancy and lactation (breastfeeding)

- during pregnancy to prevent the development of neural tube defects in the fetus

- long-term treatment with folic acid antagonists (methotrexate, a combination of sulfametaxazole / trimethoprim), anticonvulsants (phenytoin, primidone, phenobarbital). Contraindications to use - pernicious anemia

- malignant neoplasms

- cobalamin deficiency

- hypersensitivity to the components of the drug. Dosing regimen The drug is administered orally.

For the treatment of megaloblastic anemia caused by a deficiency of folic acid, 5 mg / day is prescribed for 4 months, for prophylaxis - 2.5 mg / day.

For the prevention and treatment of macrocytic anemia in malabsorption, inflammatory bowel diseases and unbalanced or inadequate nutrition - 15 mg / day, for patients with sprue disease - 5-15 mg / day.

To prevent the development of neural tube defects in the fetus - 2.5 mg / day for 4 weeks before the intended pregnancy.

Reception continues during the first trimester of pregnancy.

Higher maintenance doses can be prescribed to patients with alcoholism, as well as to patients with chronic infections and taking anticonvulsants. Overdose: No cases of overdose have been reported.

Allergic

Name ENG

FOLACIN

Clinical and pharmacological group

Vitamin preparation

ATX code

Folic acid

Dosage

5mg

Structure

1 tablet contains: Active ingredient: folic acid - 5 mg.

Excipients: ludipress [lactose monohydrate, povidone, cro-spovidone], microcrystalline cellulose, magnesium stearate.

Indications

treatment and prevention of folic acid deficiency in the presence of an unbalanced or malnutrition

treatment and prevention of anemias associated with folic acid deficiency (macrocytic hyperchromic anemia, anemia and leukopenia caused by drugs and ionizing radiation, megaloblastic anemia, post-resection anemia, sideroblastic anemia in elderly patients, anemias associated with diseases of the small intestine, sportia and malabsorption syndrome )

treatment and prevention of anemia during pregnancy and lactation (breastfeeding)

during pregnancy to prevent the development of neural tube defects in the fetus

long-term treatment with folic acid antagonists (methotrexate, a combination of sulfametaxazole / trimethoprim), anticonvulsants (phenytoin, primidone, phenobarbital).

Contraindications

pernicious anemia

malignant neoplasms

cobalamin deficiency

hypersensitivity to drug components.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

Folic acid

Specifications

Category

Vitamin and mineral complexes

Scope of the drug

Vitamins

Release form

Tablet

Manufacturer country

Croatia

Package quantity, pcs

thirty

Vacation conditions

Without recipe

Brand name

Jadran

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Vitamins

Anatomical and therapeutic characteristics

B03BB01 Folic acid

Dosage form

Pills

Dosage (volume) of the substance in the preparation

folic acid 5 mg

Expiration date in days

1095

The target audience

Adult

Package weight, g

twenty

Information on technical characteristics, delivery set, country of manufacture

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