Fleet phospho-soda solution 45ml, No. 2

• preparation for endoscopic or X-ray examination of the colon

• preparation for surgery on the colon.

Fleet Phospho-soda is prescribed for adults and adolescents over 15 years of age. For elderly patients, doses similar to those for adults are used.

You should start taking the drug on the day preceding the prescribed procedure.
If the procedure is scheduled before noon, the instructions for the morning appointment must be followed. If the procedure is scheduled for the afternoon, then the instructions for the daily appointment must be followed.

Morning appointment.
The day before the procedure.

• 7:00 Instead of breakfast, drink at least one glass (or more) of 'light liquid' or water.

• 'Light liquid' means water, soups free of solids, fruit juices without pulp, tea, coffee, clear carbonated and non-carbonated soft drinks.

• The first dose of the drug is taken immediately after breakfast. For this, the contents of one bottle (45 ml) are dissolved in half a glass (120 ml) of cold water. Then you should drink the solution and drink one (or more) glass (240 ml) of cold water.

• 13:00 Instead of lunch, drink at least three glasses (720 ml) of 'light liquid' or water, if desired, the volume can be increased.

• 19:00 Instead of dinner, drink one glass of 'light liquid' or water, if desired, the volume can be increased.

The second dose of the drug is taken immediately after dinner. Dissolve the contents of the second bottle (45 ml) in half a glass (120 ml) of cold water. Then you should drink the solution and drink one glass (240 ml) of cold water. You can drink more liquid if desired.
If necessary, you can drink 'light liquids' and water until midnight.

Daytime appointment.
The day before the procedure.

• 13:00 during lunch time you can have a light snack. No solid food should be eaten after dinner.

• 19:00 Instead of dinner, drink one glass of 'light liquid' or water, if desired, the volume can be increased.

• The first dose of the drug is taken immediately after breakfast. For this, the contents of one bottle (45 ml) are dissolved in half a glass (120 ml) of cold water. Then you should drink the solution and drink one (or more) glass (240 ml) of cold water.

• Day of the procedure.

• 7:00 Instead of breakfast, drink at least one glass (or more) of 'light liquid' or water, if desired, the volume can be increased.

The second dose of the drug is taken immediately after breakfast. Dissolve the contents of the second bottle (45 ml) in half a glass (120 ml) of cold water. Then you should drink the solution and drink one glass (240 ml) of cold water. You can drink more liquid if desired.
'Light liquids' and water can be consumed until 8:00.

Typically, the drug induces stools within half an hour to 6 hours.

1 bottle (45 ml) contains:

Active ingredients: sodium hydrogen phosphate dodecahydrate 240 mg (10.8 g); sodium dihydrogen phosphate dihydrate 542 mg (24.4 g); component of the composition without quantity;

Excipients: glycerol 99%; sodium saccharin; sodium benzoate (E211); ginger and lemon flavoring (ginger oil, alcohol, lemon oil, partially stabilized lemon oil, citric acid, water); purified water.

• hypersensitivity to drug components;

• partial or complete intestinal obstruction;

• violation of the integrity of the intestine;

• megacolon (congenital or acquired);

• acute inflammatory bowel disease;

• heart failure;

• renal failure;

• nausea, vomiting, abdominal pain;

• children and adolescents up to 15 years old.

Clinical pharmacology

Fleet Phospho-Soda is a laxative.

Pharmacodynamics

The mechanism of action of the drug is based on an increase in water retention in the lumen of the small intestine using osmotic processes. The accumulation of fluid in the ileum leads to increased peristalsis and subsequent bowel cleansing.

Pharmacokinetics

The drug has only a local effect, therefore pharmacokinetic studies are not considered necessary. Sodium phosphate is poorly absorbed from the gastrointestinal tract, but little absorption of sodium and phosphate ions occurs and is dose-dependent.

special instructions

Fleet Phospho-Soda is not used to treat constipation.

It is used with caution in elderly and debilitated patients, patients with reduced renal function, heart disease, colostomy, as well as in patients on a diet low in salt, as there is a likelihood of developing hyperphosphatemia, hypocalcemia, hypokalemia, dehydration against the background of hypernatremia and acidosis ...

The patient should be warned about the expected frequent loose stools. Very rarely, with endoscopy on the mucous membrane of the sigmoid and rectum, single or multiple aphtho-like changes were observed. These were either lymphoid follicles, or discrete formations of an inflammatory nature, or changes in the epithelium caused by the preparation. These abnormalities are not clinically significant and disappear spontaneously without treatment. Rarely, there is a prolongation of the QT interval on the ECG as a result of electrolyte imbalance such as hypocalcemia or hypokalemia.

Use with caution in individuals taking calcium channel blockers, diuretics, lithium-based drugs and other medications that can affect electrolyte levels, since there is a likelihood of hyperphosphatemia, hypocalcemia, hypokalemia, dehydration associated with hypernatremia and acidosis.

During the period of taking the drug, the absorption of drugs in the gastrointestinal tract may be delayed or even completely stopped. The effect of regularly taken medications (for example, oral contraceptives, antiepileptic drugs, antidiabetic drugs, antibiotics) may be reduced or absent altogether.

Side effects

nausea, vomiting, abdominal pain, bloating, diarrhea