Finalgon ointment d / nar. approx. tube 20g

Dosage form

Almost colorless or slightly brownish, transparent or translucent, homogeneous homogeneous ointment

Structure

1 g of ointment contains: nonivamide

(nonylic acid vanillilamide) (P5VA) 4 mg

nicoboxyl (nicotinic acid butoxyethyl ester) (NSBE) 25 mg

Excipients:

Diisopropyl adipate (Crodamol) 120 mg

colloidal silicon dioxide 20 mg

petroleum jelly (paraffin, soft white) 822 mg sorbic acid 2 mg, citronella oil 2 mg purified water 5 mg.

pharmachologic effect

Nonivamid

It is a synthetic analogue of capsaicin and has analgesic properties, which are manifested as a result of the gradual penetration of the substance into the peripheral nociceptive C-fibers and A-delta nerve fibers upon repeated application of the drug to the skin.

Nonivamide has a vasodilating effect, which is accompanied by an intense prolonged sensation of warmth, due to the stimulation of afferent nerve endings in the skin

Nicoboxil

It is a derivative of nicotinic acid, which has vasodilating properties with the participation of prostaglandins I2 and E2.

The hyperemic effect of nicoboxil (butoxyethyl ester of nicotinic acid) develops faster and has a greater intensity than the hyperemic effect of nonivamide.

Combined action

Nonivamide and nicoboxil have complementary vasodilating properties, cause flushing of the skin, increase the rate of enzymatic reactions, and activate metabolism.

The appearance of redness and an increase in skin temperature within a few minutes after application indicate the rapid penetration of the active components of the drug into the skin.

FINALGON's action is local.

The action of the drug develops within a few minutes.

the maximum effect occurs

after 20-30 minutes.

The analgesic effect of a combination of 0.4% nonivamide and 2.5% nicoboxil was demonstrated in a study of efficacy in patients with acute

nonspecific pain in the lower back It was found that in patients who used FINALGON (2 cm ointment per application and used the drug up to 3 times a day for 4 days), there was a clinically significant decrease in the intensity of pain in the lower back after 4 hours after the first application

On the last day of treatment, determined individually, Taske experienced a clinically significant reduction in pain.

In a clinical study, it was found that pain relief began after 1–2 hours.

Pharmacokinetics

Data on the pharmacokinetics of Finalgon® are not provided

Side effects

In the course of clinical studies and long-term experience with the drug, the following side effects were identified:

From the immune system: anaphylactic reactions, hypersensitivity.

From the nervous system: paresthesia, burning sensation

Respiratory system: cough, shortness of breath.

On the part of the skin and subcutaneous tissues: vesicles or pustules at the site of application, erythema, local skin reaction (for example, contact dermatitis), itching, rash, facial edema, urticaria, a feeling of heat at the site of application.

Selling features

Available without a prescription

Special conditions

The drug causes flushing of the skin, resulting in redness, a feeling of warmth, itching and burning at the site of application.

These symptoms may be more pronounced with excessive application of the drug or in the case of intense rubbing on the skin surface.

Using excessive amounts of the drug or vigorous rubbing on the surface of the skin may lead to the formation of vesicles or pustules at the site of application of the ointment.

After using FINALGON, wash your hands immediately with soap and water.

Care must be taken to avoid accidental contact with the drug.

Name ENG

FINALGON

Clinical and pharmacological group

A preparation with a local irritant and analgesic effect

ATX code

Other drugs

Dosage

25mg / g + 4mg / g x 20g

Structure

1 g of the ointment contains: nonivamide.

(nonylic acid vanillilamide) (P5VA) 4 mg.

nicoboxyl (nicotinic acid butoxyethyl ester) (NSBE) 25 mg.

Excipients: Diisopropyladipinate (Krodamol) 120 mg

colloidal silicon dioxide 20 mg

petroleum jelly (paraffin, soft white) 822 mg sorbic acid 2 mg, citronella oil 2 mg purified water 5 mg.

Indications

Arthritis

arthralgia and myalgia of rheumatic genesis

sports injuries, bruises and damage to the ligamentous apparatus

myalgia caused by excessive physical exertion

lumbago

neuritis

ishalgia

bursitis and tendovaginitis

for preliminary warming up" of muscles before physical exercises, sports competitions

as part of complex vasodilator therapy for peripheral circulatory disorders.

INN / Active ingredient

Nonivamide + nicoboxil

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 4 years

Contraindications

Hypersensitivity to nicoboxil, nonivamide or excipients of the drug

children under 12 years of age.

the drug should not be applied to sensitive skin, open wounds, inflamed skin areas, areas of skin with increased permeability: neck, lower abdomen, inner thighs.

Specifications

Category

Bruises, sprains

Scope of the drug

Musculoskeletal system

Release form

Ointment

Manufacturer country

Austria

Package quantity, pcs

one

Minimum age from

12 years

Way of introduction

Outwardly

Vacation conditions

Without recipe

Brand name

Boehringer ingelheim

Components

applicator

The amount of the dosage form in the primary package

20 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Local irritant

Anatomical and therapeutic characteristics

M02AX10 Other preparations

Dosage form

Ointment for external use

Drug action

Analgesic

,

Pain reliever

,

Vasodilator

Dosage (volume) of the substance in the preparation

1 g - nonivamide 4 mg, nicoboxil 25 mg

The target audience

Children

Expiration date in days

1095

Package weight, g

thirty

Mode of application

:

It is necessary to start the application with the lowest dose of the drug.

To do this, using the attached applicator, a column of the drug no more than 0.5 cm in size is applied to the appropriate palm-sized area of ​​skin with light rubbing movements.

To enhance the therapeutic effect, the area of ​​the skin on which the drug is applied can be covered with a woolen cloth.

Information on technical characteristics, delivery set, country of manufacture "