Finalgon cream d / nar. approx. tube 35g

Manufacturer

Boehringer Ingelheim, Austria

Structure

Nonivamide - 1.7 mg, nicoboxil - 10.8 mg.

Excipients: decyl oleate - 50 mg, emulsifier F - 10 mg, macrogol cetostearyl ether - 30 mg, stearic acid - 2 mg, cetostearyl alcohol - 20 mg, liquid paraffin - 30 mg, sorbic acid - 2 mg, vegetable perfume oil - 2 mg, purified water - 823.5 mg.

pharmachologic effect

Pharmacodynamics

Nonivamide is a synthetic analogue of capsaicin and has analgesic properties, which are manifested as a result of the gradual penetration of the active substance into the peripheral nociceptive C-fibers and A-delta nerve fibers upon repeated application of the drug to the skin.

Nonivamide has a vasodilating effect, which is accompanied by an intense, prolonged sensation of warmth, due to the stimulation of afferent nerve endings in the skin.

Nicoboxil is a derivative of nicotinic acid with vasodilating properties with the participation of prostaglandins I2 and E2.

The hyperemic effect of nicoboxil (butoxyethyl ester of nicotinic acid) develops faster and has a greater intensity than the hyperemic effect of nonivamide.

Combined action

Nonivamide and nicoboxil have complementary vasodilating properties, cause flushing of the skin, increase the rate of enzymatic reactions, and activate metabolism.

The appearance of hyperemia and an increase in skin temperature within a few minutes after application indicate the rapid penetration of the active components of the drug into the skin.

Finalgon's action manifests itself locally, develops after a few minutes and reaches a maximum after 20-30 minutes.

Pharmacokinetics

Data on the pharmacokinetics of Finalgon® are not available.

Indications

Arthritis

arthralgia and myalgia of rheumatic genesis

sports injuries, bruises and damage to the ligamentous apparatus

myalgia caused by excessive physical exertion

lumbago

neuritis

ishalgia

bursitis and tendovaginitis

for preliminary warming up" of muscles before physical exercises, sports competitions

as part of complex vasodilator therapy for peripheral circulatory disorders.

Contraindications

Hypersensitivity to nicoboxil, nonivamide or excipients of the drug

children under 12 years old.

the drug should not be applied to sensitive skin, open wounds, inflamed skin areas, skin areas with increased permeability: neck, lower abdomen, inner thighs.

Side effects

In the course of long-term experience with the drug, the following side effects were identified:

From the immune system: anaphylactic reactions, hypersensitivity.

From the nervous system: paresthesia, burning sensation of the skin.

From the respiratory system: cough, shortness of breath.

On the part of the skin and subcutaneous tissues: vesicles or pustules at the site of application, local skin reaction (for example, contact dermatitis), itching, rash, facial swelling, urticaria, a feeling of heat at the site of application.

Interaction

Drug interaction of Finalgon® with other drugs used locally or systemically has not been identified.

How to take, course of administration and dosage

Treatment should be started by applying a small amount of the drug to a small area of ​​the skin to assess the individual response.

The individual reaction to the drug can differ significantly: for some people, it will be enough to apply a small amount of ointment in order to cause the necessary warming effect.

Using the supplied applicator, a column of preparation no more than 0.5 cm in size is applied to the appropriate area of ​​the skin the size of a palm with light rubbing movements.

To enhance the therapeutic effect, the area of ​​the skin to which the drug is applied can be covered with a woolen cloth.

P

Name ENG

FINALGON

Clinical and pharmacological group

A preparation with a local irritant and analgesic effect

ATX code

Other drugs

Dosage

10.8mg / g + 1.7mg / g x 35g

Structure

nonivamide - 1.7 mg, nicoboxil - 10.8 mg.

Excipients: decyl oleate - 50 mg, emulsifier F - 10 mg, macrogol cetostearyl ether - 30 mg, stearic acid - 2 mg, cetostearyl alcohol - 20 mg, liquid paraffin - 30 mg, sorbic acid - 2 mg, vegetable perfume oil - 2 mg, purified water - 823.5 mg.

Indications

Arthritis

arthralgia and myalgia of rheumatic genesis

sports injuries, bruises and damage to the ligamentous apparatus

myalgia caused by excessive physical exertion

lumbago

neuritis

ishalgia

bursitis and tendovaginitis

for preliminary "warming up" of muscles before physical exercises, sports competitions

as part of complex vasodilator therapy for peripheral circulatory disorders.

INN / Active ingredient

Nonivamide + nicoboxil

Contraindications

Hypersensitivity to nicoboxil, nonivamide or excipients of the drug

children under 12 years of age.

the drug should not be applied to sensitive skin, open wounds, inflamed skin areas, areas of skin with increased permeability: neck, lower abdomen, inner thighs.

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Specifications

Category

Bruises, sprains

Scope of the drug

Musculoskeletal system

Release form

Cream

Manufacturer country

Germany

Package quantity, pcs

one

Minimum age from

12 years

Way of introduction

Outwardly

Vacation conditions

Without recipe

Brand name

Sanofi

The amount of the dosage form in the primary package

35 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Local irritant

Anatomical and therapeutic characteristics

M02AX10 Other preparations

Dosage form

Cream for external use

Item weight, g

35

Expiration date in days

1095

The target audience

Children

Dosage (volume) of the substance in the preparation

nicoboxil - 10.8 mg, nonivamide - 1.7 mg

Package weight, g

fifty

Mode of application

:

Treatment should be started by applying a small amount of the drug to a small area of ​​the skin to assess the individual response. The individual reaction to the drug can vary significantly: for some people it will be enough to apply a small amount of ointment in order to cause the necessary warming effect. < br> With the help of the attached applicator, a column of preparation no more than 0.5 cm in size is applied to the appropriate area of ​​the skin the size of a palm with light rubbing movements. To enhance the therapeutic effect, the area of ​​the skin to which the drug is applied can be covered with a woolen cloth. < br> With repeated use, the reaction to the ointment may decrease, which requires an increase in the dose, which is selected individually. < br> If necessary, the cream is used 2-3 times / day. < br> For preliminary warming up of muscles before physical exercises, sports competitions it is recommended to rub in about 30 minutes before their start. < br> The patient should be warned that in the absence of the desired effect within 10 days, you should consult a doctor. < br> After applying the drug to the skin, wash your hands thoroughly with soap and water.

Drug action

:

Pain reliever

,

Warming up

,

Analgesic

,

Vasodilator

Information on technical characteristics, delivery set, country of manufacture "