Ferlatum Fol oral solution, 15 ml, No. 10

- Treatment of latent and clinically significant iron deficiency (iron deficiency anemia) and folate;
- Preventive therapy for iron and folate deficiency during pregnancy, lactation, active growth; after prolonged bleeding, against the background of inadequate and unbalanced nutrition.

Ferlatum Foul is taken orally before or after meals.
To prepare a solution for oral administration, it is necessary to press firmly on the perforator of the dosing cap so that the powder spills out into the solution in the vial. Shake vigorously, remove the dosing cap and drink the solution from the bottle.
Adults: 1-2 vials per day in an amount equivalent to 40-80 mg Fe3 + and 0.235-0.470 mg of calcium folinate pentahydrate or as recommended by a doctor, in 2 divided doses.
Children (from the neonatal period): 1.5 ml / kg / day (in an amount equivalent to 4 mg / kg / day Fe3 + and 0.0235 mg / kg / day calcium folinate pentahydrate) in 2 divided doses or as recommended by a physician.
1 bottle (15 ml) contains: iron protein succinylate - 800 mg (equivalent to 40 mg Fe + 3) and 0.235 mg of calcium folinate pentahydrate (equivalent to 0.185 mg of folinic acid).
Pregnant women:
For the prevention of iron deficiency anemia - 1 bottle per day.
For the treatment of latent or clinically pronounced iron deficiency - 1-2 bottles per day in 2 divided doses.
After reaching normal levels of serum iron and hemoglobin, treatment is continued for at least 8-12 weeks, prescribing a maintenance dose.

1 bottle (15 ml) contains :
Active ingredient: iron protein succinylate - 800 mg (equivalent to 40 mg Fe + 3)
Excipients : sorbitol - 1400 mg, propylene glycol - 1000 mg, sodium methyl parahydroxybenzoate - 45 mg, sodium propyl parahydroxybenzoate - 15 mg, cherry flavor (wild black cherry flavor concentrated, vanillin, amyl acetate, small amounts of other esters, benzaldehyde, clove buds oil, propylene glycol, diethylene glycol monoethyl ether, water) - 60 mg, sodium saccharinate - 15 mg, purified water - up to 15 ml.
Each dispensing cap (container cap) contains:
Active ingredient: calcium folinate pentahydrate - 0.235 mg (equivalent to 0.200 mg calcium folinate or 0.185 mg folinic acid);
Excipients : mannitol - 99.8 mg.

- Hypersensitivity to the drug;
- Iron overload (hemochromatosis);
- Violation of iron utilization (lead anemia, sideroachrestic anemia);
- Non-iron deficiency anemia (hemolytic anemia; megaloblastic anemia caused by a lack of vitamin B12);
- Chronic pancreatitis;
- Cirrhosis of the liver.

Carefully:

Caution should be exercised in patients with: gastric ulcer and duodenal ulcer, malabsorption in pathology of the small intestine (enteritis, malabsorption syndrome, resection of the small intestine, resection of the stomach according to Billroth II with the inclusion of the duodenum).

Trade name of the drug:

Ferlatum Fol

Dosage form :

Oral solution.

Composition:

1 bottle (15 ml) contains :
Active ingredient: iron protein succinylate - 800 mg (equivalent to 40 mg Fe + 3)
Excipients : sorbitol - 1400 mg, propylene glycol - 1000 mg, sodium methyl parahydroxybenzoate - 45 mg, sodium propyl parahydroxybenzoate - 15 mg, cherry flavor (wild black cherry flavor concentrated, vanillin, amyl acetate, small amounts of other esters, benzaldehyde, clove buds oil, propylene glycol, diethylene glycol monoethyl ether, water) - 60 mg, sodium saccharinate - 15 mg, purified water - up to 15 ml.
Each dispensing cap (container cap) contains:
Active ingredient: calcium folinate pentahydrate - 0.235 mg (equivalent to 0.200 mg calcium folinate or 0.185 mg folinic acid);
Excipients : mannitol - 99.8 mg.

Description:
In a bottle: a transparent brownish solution with a pleasant characteristic cherry scent.
In the dispenser lid (container cap): powder, white with a yellowish tinge, odorless.
Pharmacotherapeutic group: Iron drug.

Pharmacological properties:
Ferlatum Fol - a preparation of iron and calcium folinate, replenishes the lack of iron and folate in the body.
The main function of iron is to carry oxygen to tissues. Iron is a part of hemoglobin, myoglobin, iron-containing enzymes, cytochromes, carries electrons and works as a catalyst for oxidation, hydroxylation and other metabolic processes.
Ferlatum Fol contains iron-protein succinylate, which is a complex compound where ferric atoms (Fe3 +) are surrounded by a semisynthetic protein carrier that prevents damage to the gastric mucosa. The protein carrier is re-dissolved in the duodenum, releasing iron at the site of its best absorption.
Trivalent iron enters the bloodstream from the intestine by active absorption, which explains the impossibility of overdose and poisoning.
Calcium folinate is a calcium salt of folinic acid that replenishes folate deficiencies in the body.

Indications for use:

- Treatment of latent and clinically significant iron deficiency (iron deficiency anemia) and folate;
- Preventive therapy for iron and folate deficiency during pregnancy, lactation, active growth; after prolonged bleeding, against the background of inadequate and unbalanced nutrition.

Contraindications:

- Hypersensitivity to the drug;
- Iron overload (hemochromatosis);
- Violation of iron utilization (lead anemia, sideroachrestic anemia);
- Non-iron deficiency anemia (hemolytic anemia; megaloblastic anemia caused by a lack of vitamin B12);
- Chronic pancreatitis;
- Cirrhosis of the liver.

Carefully:

Caution should be exercised in patients with: gastric ulcer and duodenal ulcer, malabsorption in pathology of the small intestine (enteritis, malabsorption syndrome, resection of the small intestine, resection of the stomach according to Billroth II with the inclusion of the duodenum).

Pregnancy and lactation:

The use of Ferlatum Fol is especially recommended for the prevention and treatment of iron and folate deficiency that develops during pregnancy and lactation.

Method of administration and dosage:

Ferlatum Foul is taken orally before or after meals.
To prepare a solution for oral administration, it is necessary to press firmly on the perforator of the dosing cap so that the powder spills out into the solution in the vial. Shake vigorously, remove the dosing cap and drink the solution from the bottle.
Adults: 1-2 vials per day in an amount equivalent to 40-80 mg Fe3 + and 0.235-0.470 mg of calcium folinate pentahydrate or as recommended by a doctor, in 2 divided doses.
Children (from the neonatal period): 1.5 ml / kg / day (in an amount equivalent to 4 mg / kg / day Fe3 + and 0.0235 mg / kg / day calcium folinate pentahydrate) in 2 divided doses or as recommended by a physician.
1 bottle (15 ml) contains: iron protein succinylate - 800 mg (equivalent to 40 mg Fe + 3) and 0.235 mg of calcium folinate pentahydrate (equivalent to 0.185 mg of folinic acid).
Pregnant women:
For the prevention of iron deficiency anemia - 1 bottle per day.
For the treatment of latent or clinically pronounced iron deficiency - 1-2 bottles per day in 2 divided doses.
After reaching normal levels of serum iron and hemoglobin, treatment is continued for at least 8-12 weeks, prescribing a maintenance dose.

Side effects:

In rare cases, the appearance of gastrointestinal disorders is possible, which disappear when the dose is reduced or the drug is discontinued.

Overdose:

So far, no signs of intoxication and excessive intake of Ferlatum Foul in the body have been described.

Interaction with other medicinal products:

There was no interaction of Ferlatum Fol with other drugs of their simultaneous use.
Iron absorption can be increased with the simultaneous administration of more than 200 mg of ascorbic acid and decreased with the use of antacids. Chloramphenicol causes a delayed response to iron therapy.
No pharmacological interaction was noted with concomitant treatment with H2-receptor antagonists.
Some antineoplastic and anti-leukemic drugs (aminopterin, methotrexate, and other pterin derivatives) act as folate antagonists.

Special instructions:

The continuous period of use of Ferlatum Fol should not exceed 6 months, with the exception of cases of chronic blood loss (menorrhagia, hemorrhoids, etc.) and pregnancy.
Does not affect engaging in potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions (including driving).
The drug should be used with caution in patients suffering from milk protein intolerance, in whom an allergic reaction may occur.
Ferlatum Fol contains sorbitol, therefore, patients suffering from hereditary fructose intolerance should not use the drug.

Release form:

Oral solution. 15 ml of solution in a polyethylene bottle and 100 mg of powder in a sealed dispenser lid (container-cap) with first opening control.
10 or 20 vials with instructions for use in a cardboard box.

Shelf life:

2 years. Do not use an expired drug.

Storage conditions:

At a temperature not higher than 25 ? C.

Keep out of the reach of children!

Terms of dispensing from pharmacies:

On prescription.