Fenkarol tablets 10mg, No. 20

• hay fever;

• acute and chronic urticaria;

• angioedema;

• allergic rhinitis;

• dermatoses (including eczema, psoriasis, atopic dermatitis);

• neurodermatitis;

• itchy skin.

The drug is taken orally after meals.

The dosage regimen of the drug is the same for all indications for use. The dosage of hifenadine can be influenced by the severity of the allergic reaction, the individual sensitivity of the patient, as well as the severity of possible side effects.

Adults are prescribed 50 mg 1-4 times / day or 25 mg 2-4 times / day. The maximum daily dose is 200 mg. The average course of treatment is 10-20 days. If necessary, repeat the course of treatment.

Children aged 3 to 7 years - 10 mg 2 times / day; at the age of 7 to 12 years - 10-15 mg 2-3 times / day; over 12 years old - 25 mg 2-3 times / day. The course of treatment is 10-15 days.

Side effect From the digestive system: dryness of the oral mucosa, nausea, vomiting.

From the side of the central nervous system: drowsiness, headache.

Others: allergic reactions.

White or off-white tablets

Active substance:

hifenadine hydrochloride

• pregnancy;

• lactation period (breastfeeding);

• children under 3 years of age (for tablets 10 mg and 25 mg);

• children and adolescents up to 18 years old (for 50 mg tablets);

• deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption, because the product contains sucrose;

• hypersensitivity to the components of the drug.

• The drug should be prescribed with caution for diseases of the gastrointestinal tract, liver and kidneys.

pharmachologic effect

Blocker of histamine H1 receptors. Prevents the development and facilitates the course of allergic reactions. It has antiallergic, antiexudative and antipruritic effect, preventing the development of allergic inflammation in the tissue. Weakens the effect of histamine, reduces its effect on vascular permeability (reducing permeability, has a decongestant effect), reduces its bronchospastic effect and spasmogenic effect on intestinal smooth muscles, weakens the hypotensive effect of histamine. Chifenadine reduces the content of histamine in tissues (associated with the ability to activate diamine oxidase - an enzyme that inactivates histamine). During the course of treatment, the antihistamine effect of hifenadine does not decrease. It has a moderate antiserotonin effect, shows a weak m-anticholinergic activity. Does not have a depressing effect on the central nervous system.

Indications of the drug FenkarolЃ

• hay fever;

• acute and chronic urticaria;

• angioedema;

• allergic rhinitis;

• dermatoses (including eczema, psoriasis, atopic dermatitis);

• neurodermatitis;

• itchy skin.

Dosage regimen

The drug is taken orally after meals.

The dosage regimen of the drug is the same for all indications for use. The dosage of hifenadine can be influenced by the severity of the allergic reaction, the individual sensitivity of the patient, as well as the severity of possible side effects.

Adults are prescribed 50 mg 1-4 times / day or 25 mg 2-4 times / day. The maximum daily dose is 200 mg. The average course of treatment is 10-20 days. If necessary, repeat the course of treatment.

Children aged 3 to 7 years - 10 mg 2 times / day; at the age of 7 to 12 years - 10-15 mg 2-3 times / day; over 12 years old - 25 mg 2-3 times / day. The course of treatment is 10-15 days.

Side effect From the digestive system: dryness of the oral mucosa, nausea, vomiting.

From the side of the central nervous system: drowsiness, headache.

Others: allergic reactions.

Contraindications for use

• pregnancy;

• lactation period (breastfeeding);

• children under 3 years of age (for tablets 10 mg and 25 mg);

• children and adolescents up to 18 years old (for 50 mg tablets);

• deficiency of sucrase / isomaltase, fructose intolerance, glucose-galactose malabsorption, because the product contains sucrose;

• hypersensitivity to the components of the drug.

• The drug should be prescribed with caution for diseases of the gastrointestinal tract, liver and kidneys.

P USAGE Pregnancy and breast-feeding

The use of the drug during pregnancy is contraindicated.

If necessary, treatment with the drug breastfeeding should be discontinued.

Application for violations of liver function

The drug should be prescribed with caution for liver diseases.

Application for impaired renal function

With caution, the drug should be prescribed for kidney disease.

Application in children

The use of the drug in the form of 10 mg and 25 mg tablets is contraindicated in children under 3 years of age, in the form of 50 mg tablets - in children and adolescents up to 18 years.

special instructions

The absence of a pronounced m-anticholinergic effect allows prescribing the drug to patients for whom antihistamines with m-anticholinergic activity are contraindicated.

Use in pediatrics

Children are recommended to prescribe FenkarolЃ in the form of tablets of 10 mg or 25 mg.

Influence on the ability to drive vehicles and mechanisms

FenkarolЃ is approved for use by persons whose work requires an increased concentration of attention and a quick psychomotor reaction (driving vehicles and working with mechanisms), but it is recommended to first determine (by short-term prescription) whether the drug has a sedative effect.

Overdose

Symptoms: dry mucous membranes, headache, vomiting, abdominal pain and other symptoms of dyspepsia.

Treatment: gastric lavage, intake of activated charcoal, symptomatic therapy.

In case of overdose, the patient should consult a doctor.

Drug interactions

Hifenadine does not enhance the inhibitory effect of ethanol and hypnotics on the central nervous system.

Possessing weak m-anticholinergic properties, the drug can reduce gastrointestinal motility, which helps to increase the absorption of slowly absorbed drugs (for example, indirect anticoagulants - coumarins).

Storage conditions of the drug FenkarolЃ

The drug should be stored out of the reach of children, in a dry, dark place at a temperature not exceeding 25 ? C.