Fenistil gel 0.1%, 30 g

• Itching of various origins (not associated with cholestasis), for example, itchy dermatoses, eczema, urticaria, insect bites;

• sunburn,

• household and industrial burns (mild).

Outwardly.

The gel is applied to the affected area of ??the skin 2Ц4 times a day.

In cases of severe itching or widespread skin lesions, the simultaneous use of oral forms of antihistamines is recommended.

The active substance is dimethindene maleate.
1 g of gel for external use contains 1 mg of dimethindene.

Excipients:
benzalkonium chloride, disodium edeteate, carbopol 974 R (carbomer 974 R), propylene glycol, sodium hydroxide (30% m / m solution), purified water.

• Hypersensitivity to dimethindene and other components that make up the drug,

• angle-closure glaucoma,

• hyperplasia of the prostate,

• children's age up to 1 month, especially premature ones.

With caution - pregnancy 1 trimester, lactation.

Trade name: Fenistil

International non-proprietary name:

dimethindene.

Chemical name: 2- (2-dimethylaminoethyl) -3- [2- (2-pyridyl) ethyl] - (1H) -indene maleate

Dosage form:

gel for external use.

Composition:

The active substance is dimethindene maleate.
1 g of gel for external use contains 1 mg of dimethindene.

Excipients:
benzalkonium chloride, disodium edeteate, carbopol 974 R (carbomer 974 R), propylene glycol, sodium hydroxide (30% m / m solution), purified water.

Description.

Homogeneous colorless gel. Transparent or slightly opalescent. Virtually odorless.

Pharmacotherapeutic group:

Antiallergic agent-H1-histamine receptor blocker.

Pharmacological properties:

Antihistamine, anti-allergic and antipruritic agent. H1-histamine receptor blocker is a competitive histamine antagonist. The drug reduces the increased capillary permeability associated with allergic reactions. When applied to the skin, Fenistil gel reduces itching and irritation caused by skin-allergic reactions. The drug also has a pronounced local anesthetic effect. It also has antikinin and weak anticholinergic effects. When applied topically, thanks to the gel base, it has a quick onset of action - after a few minutes, the maximum effect - after 1-4 hours.

Pharmacokinetics. When applied topically, it penetrates well into the skin; systemic bioavailability - 10%.

Indications for use:

• Itching of various origins (other than those associated with cholestasis), for example: itchy dermatoses, eczema, urticaria, insect bites.

• Sunburn,

• household and industrial burns (mild).

Contraindications:

• Hypersensitivity to dimethindene and other components that make up the drug,

• angle-closure glaucoma,

• hyperplasia of the prostate,

• children's age up to 1 month, especially premature ones.

With caution - pregnancy 1 trimester, lactation.

Use during pregnancy and lactation:
The use of the drug in the first three months of pregnancy is possible only after consulting a doctor In the II and III trimesters of pregnancy, as well as during lactation, Fenistil gel should not be used on large areas of the skin, especially in the presence of inflammation or bleeding. Breastfeeding mothers should not apply the drug to the nipples of the mammary glands.

Method of administration and dosage:

Outwardly.

The gel is applied to the affected area of ??the skin 2-4 times a day.

In cases of severe itching or widespread skin lesions, the simultaneous use of oral forms is recommended.

Side effects

Dry, burning skin. In rare cases, skin rash and itching.

Overdose:

overdose cases are not described.

Interactions: not described.

special instructions

In infants and young children, the drug should not be used on large areas of the skin, especially in the presence of inflammation or bleeding.
In case of severe itching or in case of damage to large areas of the skin, the drug can be used only after consulting a doctor.
When using Fenistil gel on large areas of the skin, exposure to sunlight should be avoided.
If during the period of application of Fenistil gel the severity of the symptoms of the disease does not decrease or, on the contrary, increases, it is necessary to consult a doctor.
Ineffective for pruritus associated with cholestasis.

Release form:

Gel for external use, 30 g in aluminum tubes with a polypropylene lid. The tube together with the instructions for use is packed in a cardboard box.

Shelf life:

3 years. Do not use after the expiration date.

Storage conditions:

At temperatures below 25 ? C, out of the reach of children.

Terms of dispensing from pharmacies:

Without recipe.