Febrofid gel 2.5% 30g
Dosage:
2.5% x 30g
2.5% x 50g
Category
Bruises, sprains
Scope of the drug
Musculoskeletal system
Release form
Gel
Manufacturer country
Poland
Package quantity, pcs
one
Release form, composition and packaging
Gel for external use 2.5% from colorless to light yellowish, transparent or slightly opalescent.
100 g
ketoprofen lysine salt 2.5 g,
-which corresponds to the content of ketoprofen 1.6 g
macrogol 200 - 5 g, methyl parahydroxybenzoate - 0.15 g, propyl parahydroxybenzoate - 0.05 g, carbomer - 1.5 g, trolamine - 2.5 g, purified water - up to 100 g.
30 g - aluminum tubes (1) - cardboard packs.
50 g - aluminum tubes (1) - cardboard packs.
pharmachologic effect
NSAIDs for external use.
It has anti-inflammatory, anti-exudative and analgesic effects.
It is used for lesions of joints, tendons, ligaments, muscles, skin, veins, lymphatic vessels and lymph nodes.
With articular syndrome, it leads to a reduction in joint pain at rest and during movement, reduces morning stiffness and swelling of the joints.
Pharmacokinetics
Ketoprofen penetrates well through the skin, which provides a local analgesic and anti-inflammatory effect.
The bioavailability of the gel is about 5%.
Plasma protein binding - 99%.
Does not accumulate in the body.
Metabolized in the liver.
About 80% of the dose taken is excreted in the urine in the form of metabolites, less than 10% is excreted unchanged.
Indications for use
As a drug for external use in symptomatic treatment:
- pain in the spine
- neuralgia
- myalgia
- inflammatory and degenerative diseases of the musculoskeletal system (including arthritis, bursitis, synovitis, tendonitis, lumbago)
- uncomplicated injuries (including sports, dislocations, sprains or ruptures of ligaments and tendons, bruises, post-traumatic pain)
- as part of combination therapy for inflammatory diseases of the veins (phlebitis, periphlebitis), lymphatic vessels, lymph nodes (lymphangitis, superficial lymphadenitis).
Contraindications for use
- weeping dermatoses, eczema
- infected abrasions, wounds, burns
- III trimester of pregnancy
- lactation period (breastfeeding)
- hypersensitivity to ketoprofen and / or other components of the drug
- hypersensitivity to other NSAIDs (ketoprofen can cause bronchospasm in persons sensitive to acetylsalicylic acid and other NSAIDs).
Dosage regimen
The drug is intended for external use.
Apply a small amount (strip 3-5 cm long) of gel 2-3 times / day to the appropriate area of the skin and rub in lightly.
It is not necessary to apply a dry dressing as
the gel is well absorbed through the skin, has no odor, does not contain dyes, does not leave greasy spots, does not stain clothes.
Overdose
Due to the low systemic absorption, an overdose of Febrofid is unlikely.
Side effect
Possibly: allergic reactions, skin flushing, photosensitivity, skin exanthema, purpura.
Drug interactions
With frequent and prolonged use, symptoms of interaction with other drugs may appear (the same as with systemic use).
When taken together with other NSAIDs, GCS, ethanol, corticotropin, ulceration and the development of gastrointestinal bleeding are possible.
Concomitant use with oral anticoagulants, heparin, thrombolytics, antiplatelet agents, cefoperazone, cefamandol increases the risk of bleeding.
Ketoprofen reduces the effect of antihypertensive drugs and diuretics (inhibition of prostaglandin synthesis).
Increases the hypoglycemic effect of insulin and oral hypoglycemic drugs (dose adjustment is necessary).
Co-administration with sodium valproate causes impaired platelet aggregation.
Increases the concentration of verapamil and nifedipine in blood plasma.
Application during pregnancy and lactation
In I and II trim
Name ENG
FEBROFID
Clinical and pharmacological group
NSAIDs for external use
ATX code
Ketoprofen
Dosage
2.5% x 30g
Structure
Active ingredient: Ketoprofen lysine salt, 2.5 g / 100.0 g gel.
Excipients: polyethylene glycol, methyl hydroxybenzoate, propyl hydroxybenzoate, carbomer, triethanolamine, purified water.
Indications
As a drug for external use in symptomatic treatment:
back pain
neuralgia
myalgia
inflammatory and degenerative diseases of the musculoskeletal system (including arthritis, bursitis, synovitis, tendonitis, lumbago)
uncomplicated injuries (including sports, dislocations, sprains or ruptures of ligaments and tendons, bruises, post-traumatic pain)
as part of combination therapy for inflammatory diseases of the veins (phlebitis, periphlebitis), lymphatic vessels, lymph nodes (lymphangitis, superficial lymphadenitis).
Storage conditions and periods
In a dark place at a temperature not exceeding 25 degrees.
Expiration date: 3 years
Contraindications
weeping dermatoses, eczema
infected abrasions, wounds, burns
III trimester of pregnancy
lactation period (breastfeeding)
hypersensitivity to ketoprofen and / or other components of the drug
hypersensitivity to other NSAIDs (ketoprofen can cause bronchospasm in persons sensitive to acetylsalicylic acid and other NSAIDs).
INN / Active ingredient
Ketoprofen
Specifications
Category
Bruises, sprains
Scope of the drug
Musculoskeletal system
Release form
Gel
Manufacturer country
Poland
Package quantity, pcs
one
Way of introduction
Outwardly
Vacation conditions
Without recipe
Brand name
Medana
The amount of the dosage form in the primary package
30 g
Primary packaging type
Tuba
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
Non-steroidal anti-inflammatory drug
Anatomical and therapeutic characteristics
M02AA10 Ketoprofen
Dosage form
Gel for external use
Item weight, g
thirty
Dosage (volume) of the substance in the preparation
Ketoprofen lysine salt, 2.5 g / 100.0 g
Expiration date in days
1095
Package weight, g
45
Mode of application
:
The drug is intended for external use. < br> A small amount (strip 3-5 cm long) of gel 2-3 times / day, apply to the appropriate area of the skin and rub in lightly. < br> There is no need to apply a dry bandage, since the gel is good absorbed through the skin, odorless, does not contain dyes, does not leave greasy spots, does not stain clothes.
Drug action
:
Pain reliever
,
Anti-inflammatory
,
Analgesic
,
Antiexudative
Information on technical characteristics, delivery set, country of manufacture