Exported powder 10g, No. 20

constipation, intestinal dysbiosis;

the need to regulate the stool for medical purposes (bowel cleansing in preparation for endoscopic and X-ray examinations, surgical interventions on the rectum, anal sphincter and the area adjacent to it);

hepatic encephalopathy, hepatic precoma and coma, hyperammonemia.

Inside, during meals, mixing with various drinks (including water, tea, coffee, juices) or liquid food.

Constipation and dysbiosis. The drug should be taken once, the entire daily dose at once, at one time. Adults - 20 g / day (4 teaspoons of powder); children 12-16 years old - 10-20 g / day (2-4 tsp of powder); 6-12 years old - 5-10 g / day (1-2 tsp of powder); 1Ц6 years old - 2.5Ц5 g / day (0.5Ц1 teaspoon of powder).

The drug should induce stool 1 time per day; after the onset of a stable laxative effect for several days of using the drug, its dose can be reduced. In some cases, half of the recommended daily dose is enough to obtain the desired effect. The minimum course of therapy, after which you should consult a doctor, is 5 months. The use of the drug in children is recommended under medical supervision.

Stool regulation for medical purposes. 20 g of the drug, diluted in 1 liter of water, is taken 3 times (at 12, 15 and 18 hours) on the eve of medical procedures.

Hepatic encephalopathy, hepatic precoma and coma, hyperammonemia. The dose of the drug should be selected individually for each patient, depending on the severity of the disease and the individual response to the drug. The initial daily dose is usually 0.5Ц0.7 g / kg. This dose is divided into 3 single doses. The dose should be adjusted to induce two soft stools per day.

individual intolerance to lactitol;

galactosemia;

intestinal obstruction;

suspicion of organic damage to the gastrointestinal tract;

abdominal pain;

rectal bleeding of unknown origin.

pharmachologic effect

Laxative drug. In the large intestine, lactitol is broken down under the action of the intestinal flora into low molecular weight organic acids, which leads to an increase in osmotic pressure in the large intestine, an increase in the volume of feces, their softening, facilitation of bowel movements and normalization of bowel function. The laxative effect usually occurs within 24 hours after using the drug (delay is due to the passage of the drug through the gastrointestinal tract). At the beginning of the course of treatment, a delay in the laxative effect of the drug is possible, the effect may occur on the second or third day of its use. In patients with hepatic encephalopathy or hepatic coma (or precoma), the effect is achieved due to the migration of ammonia from the blood to the large intestine (due to a decrease in PH, an increase in osmotic pressure in the intestinal lumen),removal of trapped ammonium ions and other nitrogen-containing toxic substances from the colon. Lactitol inhibits proteolytic bacteria and increases the number of acidophilic bacteria.

Pharmacokinetics

Lactitol exerts its effect only in the large intestine, where it is completely absorbed after ingestion. It is absorbed in minimal amounts unchanged (no more than 0.5-2% of the dose taken).

Side effect

At the beginning of treatment, you may feel abdominal discomfort, flatulence. These phenomena, as a rule, disappear with continued use of the drug, as you adapt to it. In the case of using the drug in high doses for a long time in the treatment of hepatic encephalopathy in a patient, due to diarrhea, electrolyte imbalance may develop. Application in children

Children aged 1-6 years are prescribed 2.5-5 g (1 / 2-1 teaspoon of powder) / day; children aged 6-12 years - 5-10 g (1-2 teaspoons of powder) / day; children aged 12-16 years - 10-20 g (2-4 teaspoons of powder) / day; adults - 20 g (4 teaspoons of powder) / day. special instructions

Lactitol has a low calorie content (2 kcal / g), does not affect blood glucose levels and can be used in patients with diabetes mellitus. During the entire course of using the drug, an increased fluid intake is desirable. Influence on the ability to drive vehicles and use mechanisms

The use of Exportal does not affect psychomotor functions associated with driving a car or controlling machines and mechanisms.

Overdose

Symptoms: diarrhea, in rare cases, vomiting is possible.

Treatment: symptoms of overdose are usually eliminated by reducing the dose of the drug

Drug interactions

While taking Exportal with enteric preparations with pH-dependent release, it should be borne in mind that lactitol lowers the pH of the intestine. It is not recommended to use ExportalЃ within 2 hours after taking other medicines.