Exorolfinlac nail polish 5%, 2.5ml

• Treatment of fungal nail infections caused by dermatophytes, yeasts and molds;

• prevention of fungal infections of nails. '

Outwardly.

Apply to affected finger or toenails 1 to 2 times a week as follows:

1. Before using the preparation, remove, if possible, the affected areas of the nail (especially from its surface) using the supplied nail file.

2. Then clean and degrease the surface of the nail with the supplied cleaning cloth. Before each subsequent use of the drug, it is also necessary to process the affected nails with a file and then remove the remaining layer of varnish with a cleaning cloth.

3. Immerse the applicator in the bottle with varnish and then carefully remove it, without erasing the excess varnish on the neck of the bottle.

4. Using the applicator, apply the varnish evenly over the entire surface of the affected nail. The above procedure is repeated for each affected nail.

5. Let the varnish dry for about 3 minutes.

6. Wipe the applicator with the cleansing pad used to clean the nail, while avoiding contact between the treated nails and the cleansing pad.

Close the bottle tightly immediately after the end of the procedure. Throw away the used napkin.

Application of decorative nail polish is possible no earlier than 10 minutes after using Exorolfinlac nail polish.

When using the drug Exorolfinlac again, it is necessary to carefully remove the remaining decorative varnish from the nails, then, using the supplied files, treat the affected areas of the nails and remove the remaining layer of varnish with cleaning wipes.

Wash your hands thoroughly at the end of the procedure. If the varnish was applied to the fingernails, wait until it dries completely first.

After the varnish has dried, regular washing of hands and feet with soap is allowed.

Treatment should be continued until the regeneration of the nail (disappearance of possible manifestations / symptoms of fungal infection: discoloration / destruction of nail plates / crumbling / fragility / thickening of nails, etc.) and complete healing of the affected area.

The average treatment duration is 6 months for fingernails and 9-12 months for toenails. Due to the slow growth of the nail plates, the first signs of improvement may become noticeable only after 2 to 3 months of using the drug. If there are no signs of improvement after 3 months, it is recommended to consult a doctor. '

Composition for 1 ml:

The active ingredient is Amorolfine hydrochloride (equivalent to amorolfine base) 55, 74 (50.0) mg.

Excipients - Methacrylic acid copolymer (Eudragit RL PO) 125.0 mg Triacetin 10.5 mg Butyl acetate 50.0 mg Ethyl acetate 150.0 mg Ethanol 480.0 mg '

Hypersensitivity to amorolfine.

pharmachologic effect

Antifungal agent for external use. Possesses fungistatic and fungicidal action. Damages the cell membrane of fungi, mainly by disrupting the synthesis of sterols. Reduces the content of ergosterol, causes the accumulation of abnormal non-planar sterol stereoisomers. Active against yeasts of the genus Candida spp., Pityrosporum spp., Malassezia spp., Cryptococcus spp., Dermatophytes (Trichophyton spp., Microsporum spp., Epidermophyton spp.), Mold fungi (Altemaceae, Hendersatiis), Scopulari Cladosporium, Fonsecaea, Wangiella), dimorphic fungi (Coccidioides, Histoplasma spp., Sporothrix) and actinomycetes.

Pharmacokinetics

When applied externally in appropriate dosage forms, systemic absorption is negligible.

Side effect

Local reactions: burning, flushing, itching.

Application during pregnancy and lactation

Contraindicated: pregnancy, lactation.

Application in children

Contraindicated: neonatal period and early childhood.

special instructions

It is not recommended to use cosmetic nail polish or false nails during treatment. Impervious gloves should be worn when handling organic solvents. Files used to treat affected nails should not be used on healthy nails.