Essentiale forte N solution for injection 250mg / ml, 5 ml No. 5

Fatty degeneration of the liver (including diabetes mellitus); acute and chronic hepatitis, liver cirrhosis, liver cell necrosis, hepatic coma and precoma, toxic liver damage; toxicosis of pregnancy; pre- and postoperative treatment, especially during operations in the area of ??the hepatobiliary zone; psoriasis; radiation syndrome.

In the absence of other doctor's recommendations, slowly intravenously inject 1-2 ampoules (5-10 ml) or in severe cases 2-4 (10-20 ml) ampoules per day. The contents of two ampoules can be administered simultaneously. Do not mix with other medicines in the same syringe.
It is recommended to supplement parenteral administration with oral administration of the drug as soon as possible.

5 ml of solution contains:
Active ingredient: phosphatidylcholine from soybeans of dried substance, containing 93% (3-sn-phosphatidyl) choline: synonyms - 'essential phospholipids', 'EPLЃ' - 250 mg.
Other ingredients: benzyl alcohol - 45 mg, deoxycholic acid - 115 mg, sodium chloride - 12 mg, sodium hydroxide - 11.5 mg, riboflavin - 0.5 mg,? - tocopherol - 0.75 mg, ethanol - 16.304 mg, water for injection - 4543, 680 mg.

In case of hypersensitivity to any ingredient, the drug should not be used.
Since this solution contains benzyl alcohol, it should not be used to treat children under 3 years of age.

Trade name: Essentiale N

Dosage form:

solution for intravenous administration.

Composition:

5 ml of solution contains:
Active ingredient: phosphatidylcholine from soybeans of dried substance, containing 93% (3-sn-phosphatidyl) choline: synonyms - 'essential phospholipids', 'EPLЃ' - 250 mg.
Other ingredients: benzyl alcohol - 45 mg, deoxycholic acid - 115 mg, sodium chloride - 12 mg, sodium hydroxide - 11.5 mg, riboflavin - 0.5 mg,? - tocopherol - 0.75 mg, ethanol - 16.304 mg, water for injection - 4543, 680 mg.

Description:
Transparent yellow solution.

Pharmacotherapeutic group
Hepatoprotective agent. ATX code: A05C.

Pharmacological properties
The drug provides the liver, the metabolic activity of which is impaired, with a high dose of ready-to-digest, high-energy 'essential phospholipids'. These 'essential phospholipids' are ideally combined with naturally occurring endogenous phospholipids in chemical structure. They mainly penetrate the liver cells, invading their membranes.

'Essential phospholipids':

• normalize liver function and enzymatic activity of liver cells;

• reduce the level of energy consumption of the liver;

• promote the regeneration of liver cells;

• convert neutral fats and cholesterol into forms that facilitate their metabolism;

• stabilize the physical and chemical properties of bile.

Indications for use
Fatty degeneration of the liver (including diabetes mellitus); acute and chronic hepatitis, liver cirrhosis, liver cell necrosis, hepatic coma and precoma, toxic liver damage; toxicosis of pregnancy; pre- and postoperative treatment, especially during operations in the area of ??the hepatobiliary zone; psoriasis; radiation syndrome.

Contraindications
In case of hypersensitivity to any ingredient, the drug should not be used.
Since this solution contains benzyl alcohol, it should not be used to treat children under 3 years of age.

Dosage and administration
Unless otherwise recommended by the doctor, slowly intravenously inject 1-2 ampoules (5-10 ml) or, in severe cases, 2-4 (10-20 ml) ampoules per day. The contents of two ampoules can be administered simultaneously. Do not mix with other medicines in the same syringe.
It is recommended to supplement parenteral administration with oral administration of the drug as soon as possible.

Side effect
Very rarely, when high doses of Essentiale N are administered, gastrointestinal upset (diarrhea) may occur.

Interaction with other medicinal products
So far not known.

Special instructions
Use only clear solution!

Release form
5 ml of the drug in dark glass ampoules with clamp. 5 ampoules in a PVC strip packaging. 1 contour package together with instructions for use in a cardboard box.

Storage conditions
At temperatures from + 2 ? C to + 8 ? C, out of the reach of children.

Shelf life is
3 years. After the expiration date, the drug cannot be used.

Terms of dispensing from pharmacies
Prescription. List B.