Eskuzan oral solution 20ml

Special Price $12.74 Regular Price $20.00
In stock
SKU
OTC10201896
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Category

Diseases of the veins

Scope of the drug

Heart, vessels, blood

Release form

Solution

Manufacturer country

Germany

Package quantity, pcs

one

Description

Release form, composition and packaging

?

Oral solution from yellow to reddish-brown, clear or slightly cloudy, with a characteristic odor

sediment may form during storage.

100 g

dry extract of horse chestnut seeds (5-7: 1) 4.725 g

thiamine hydrochloride 500 mg

ethanol 96% - 26.4 g, purified water - 67.675 g, lactose monohydrate - 432 mg, colloidal silicon dioxide 243 g.

Extractant: ethanol 60 vol.% 20 ml - dark glass vials with a dropper stopper (1) - cardboard packs.

pharmachologic effect

A drug used for disorders of venous circulation.

Contains horse chestnut fruit extract, has anti-exudative, venotonic effect.

It has been established that horse chestnut fruit extract reduces the concentration of lysosomal enzymes, as a result of which the disintegration of mucopolysaccharides in the region of the capillary walls decreases.

Aescusan reduces vascular permeability, preventing the filtration of low molecular weight proteins, electrolytes and water into the intercellular space.

In randomized double-blind and crossover studies, there was a decrease in transcapillary filtration and a significant decrease in edema, a decrease in the feeling of heaviness, fatigue, tension, itching, pain.

Pharmacokinetics

Absorption and distribution After oral administration of 50 mg of horse chestnut fruit extract, Cmax in blood plasma is reached after 2.35 hours and is 25.31 ng / ml.

Plasma protein binding is 84%.

Excretion T1 / 2 is 19.87 hours. After oral administration, 0.11% of horse chestnut extract is excreted by the kidneys in the form of escin.

Indications for use

Chronic venous insufficiency of varicose and post-thrombotic genesis and its complications, incl.

diseases associated with functional impairment of blood supply: - edema, cramps in the calf muscles

- pain and feeling of heaviness in the legs

- phlebeurysm

- hemorrhoids.

Contraindications for use

- hypersensitivity to drug components.

Dosage regimen

Assign inside 12-15 drops 3 times / day.

The drug should be taken before meals with a small amount of liquid.

Shake the contents of the bottle before taking the drug.

Overdose

To date, no cases of drug overdose have been reported.

Side effect

Rarely: rarely - irritation of the gastrointestinal mucosa.

Drug interactions

The effect of thiamine, which is part of the drug Eskuzan, decreases when used simultaneously with sulfite-containing infusion solutions.

Application during pregnancy and lactation

There are clinical data on the use of Aescusan during pregnancy in patients with varicose veins and peripheral venous edema.

Aescuzan should be used with caution during lactation, because

the product contains ethanol.

Special instructions The drug contains 31% by volume ethanol.

With prolonged storage, the solution may become cloudy and a precipitate forms, which does not affect the effectiveness of the drug.

Name ENG

AESCUSAN

Clinical and pharmacological group

Phytopreparation used for disorders of venous circulation

ATX code

Other drugs that reduce capillary permeability

Dosage

20ml

Structure

100 g of oral solution contains: Active ingredients: horse chestnut seed dry extract (Hippocastani extractum siccum normatum) 5–7: 1 4.725 g (extractant - ethanol 60% v / v), thiamine hydrochloride 0.5 g.

Excipients: ethanol 96% - 26.4 g

purified water - 67.675 g

lactose monohydrate - 0.432 g

colloidal silicon dioxide - 0.243.

Indications

Chronic venous insufficiency of varicose and post-thrombotic genesis and its complications, incl.

diseases associated with functional impairment of blood supply:

swelling, cramps in the calf muscles

pain and feeling of heaviness in the legs

phlebeurysm

hemorrhoids.

Storage conditions and periods

At a temperature of 8-25 degrees.

Expiration date: 3 years

INN / Active ingredient

thiamine hydrochloride, horse chestnut seed dry extract

Contraindications

hypersensitivity to drug components

Specifications

Category

Diseases of the veins

Scope of the drug

Heart, vessels, blood

Release form

Solution

Manufacturer country

Germany

Package quantity, pcs

one

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Volume, ml.

20 ml

Brand name

Queisser pharma

The amount of the dosage form in the primary package

20 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Herbal venotonic agent

Anatomical and therapeutic characteristics

C05CX Drugs that reduce capillary permeability, others

Dosage form

Oral solution

Expiration date in days

1095

Package weight, g

fifty

Mode of application

:

Inside, before meals.

Before use, dilute in a little water. < br> 12-15 drops 3 times a day.

The duration of therapy is determined by the attending physician.

Shake well before use.

Dosage (volume) of the substance in the preparation

:

horse chestnut seeds dry extract (Hippocastani extractum siccum normatum) 5-7: 1 4.725 g (extractant - ethanol 60% v / v), thiamine hydrochloride - 0.5 g.

Information on technical characteristics, delivery set, country of manufacture

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