Erinit tablets 10mg, No. 50

Prevention of angina attacks.

Inside (1 hour before meals) 10-20 mg (1-2 tablets) 3-4 times a day, if necessary - up to 40 mg 4 times a day, it is permissible to prescribe 80 mg 2 times a day.

To prevent nocturnal attacks of angina pectoris, 20 mg is prescribed at bedtime.

The course of treatment usually lasts 2-4 weeks.

Repeated courses are prescribed by a doctor.

1 tablet contains erinita

Tablet mass-granules 0.25 g, which includes: Erinita 0.01 g, excipients (potato starch, dextrose, talc, stearic acid, sugar).

Hypersensitivity to the drug and other organic nitrates, severe arterial hypotension, collapse, shock, acute myocardial infarction with orthostatic hypotension, hemorrhagic stroke, traumatic brain injury, cerebrovascular accident (especially hemorrhagic stroke), angle-closure glaucoma, pregnancy, lactation period , concomitant use with phosphodiesterase inhibitors, age up to 18 years (efficacy and safety have not been established).

Tradename:

Erinith

Dosage form:

pills

Composition:

1 tablet contains erinita

Tablet mass-granules 0.25 g, which includes: Erinita 0.01 g, excipients (potato starch, dextrose, talc, stearic acid, sugar).

Description: tablets of white color, slightly marble, biconvex shape.

Pharmacotherapeutic group:

vasodilating agent - nitrate

ATX code [C01DA05]

Pharmacological properties

Venous vasodilator with antianginal effect. Stimulates the formation of nitric oxide in the vascular wall, which is an endothelial relaxing factor. Reduces preload (expansion of peripheral veins and a decrease in blood flow to the right atrium) and afterload (OPSS) on the heart; reduces myocardial oxygen demand.

Restores blood flow through small eidocardial vessels, improves - in the epicardial coronary arteries, increases exercise tolerance in patients with ischemic heart disease (IHD), angina pectoris.

In heart failure, it helps unload the myocardium by reducing preload. Reduces pressure in the pulmonary circulation.

Compared with nitroglycerin, it has a slower but more prolonged effect (up to 10 hours). When taken orally, the onset of the effect is after 30-45 minutes (with sublingual - after 15-20 minutes), duration is 4-5 hours.

Indications for use

Prevention of angina attacks.

Contraindications

Hypersensitivity to the drug and other organic nitrates, severe arterial hypotension, collapse, shock, acute myocardial infarction with orthostatic hypotension, hemorrhagic stroke, traumatic brain injury, cerebrovascular accident (especially hemorrhagic stroke), angle-closure glaucoma, pregnancy, lactation period , concomitant use with phosphodiesterase inhibitors, age up to 18 years (efficacy and safety have not been established).

Method of administration and dosage

Inside (1 hour before meals) 10-20 mg (1-2 tablets) 3-4 times a day, if necessary - up to 40 mg 4 times a day, it is permissible to prescribe 80 mg 2 times a day.

To prevent nocturnal attacks of angina pectoris, 20 mg is prescribed at bedtime.

The course of treatment usually lasts 2-4 weeks.

Repeated courses are prescribed by a doctor.

Side effect

Allergic reactions, headache, tinnitus, dizziness, nausea, weakness, tachycardia, fatigue, anxiety, increased sweating, decreased blood pressure (BP), orthostatic hypotension; sometimes there is a disorder of bowel function (diarrhea).

Interaction with other medicinal products

If taken simultaneously with other medicines, consult your doctor.
Under the influence of dihydroergotamine, the antianginal effect of Erinit may decrease. The combination of these drugs is considered irrational. The combination with propranolol is rational, since the antianginal effect of Erinit is enhanced. Ethanol enhances the action of Erinit.

special instructions

For the relief of angina attacks, the drug is of little use due to the slow onset of the effect.

It is necessary to exclude the use of ethanol in the course of treatment.

With prolonged use, a decrease in the therapeutic effect is possible (due to the development of tolerance).

When using the drug once a day in combination with other antianginal drugs, the risk of developing tolerance is reduced.

Release form

Tablets 10 mg.
10 tablets in a blister strip packaging.
1 or 5 blisters together with instructions for use are placed in a pack.
For hospitals: 420 blisters with the appropriate number of instructions for use are placed in a cardboard box.

Storage conditions

In a dark place at a temperature not exceeding 25 ? C.
Keep out of reach

Shelf life

3 years. Do not use after the expiration date.

Conditions of dispensing from pharmacies

On prescription.