Enterosgel sweet paste for oral administration, 225 g

It is used in adults and children as a detoxifying agent for the following diseases and conditions:

acute and chronic intoxication of various origins (chemical agents of polytropic action, xenobiotics, incorporated radionuclides, compounds of lead, mercury, arsenic, oil products, organic solvents, nitrogen oxides, fluorides, heavy metal salts);

acute poisoning with potent and poisonous substances, incl. medicines, alkaloids, alcohol, incl. during the period of withdrawal symptoms;

acute intestinal infections of any genesis as part of complex therapy (toxicoinfections, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbiosis);

purulent-septic diseases, accompanied by intoxication of varying severity as part of complex therapy;

allergic diseases, food and drug allergies;

hyperbilirubinemia (viral hepatitis); hyperazotemia (chronic renal failure);

dysbiosis after antibiotic treatment;

recommended for the prevention of residents of ecologically unfavorable regions and workers of hazardous industries.

Inside, 1-2 hours before or after meals or other medications, with water.

It is recommended to stir the required amount of the drug in a glass in a triple volume of water at room temperature or take it orally with water.

Dosage for adults - 22.5 g (1.5 tablespoons) or 1 packet 3 times a day. The daily dose is 67.5 g (3 packets).

Children aged 5 to 14 years old - 15 g (1 tablespoon) 3 times a day. The daily dose is 45 g (2 packets).

Children under the age of 5 years - 7.5 g (0.5 tablespoons) 3 times a day. The daily dose is 22.5 g (1 packet).

It is recommended for infants to stir 2.5 g (0.5 tsp) of the drug in a triple volume of breast milk or water and give it before each feeding (6 times a day).

For the prevention of chronic intoxication - 22.5 g (1 packet) 2 times a day for 7-10 days monthly.

In case of severe intoxication during the first 3 days, the dose of the drug can be doubled.

The duration of treatment for acute poisoning is 3-5 days, and for chronic intoxications and allergic conditions 2-3 weeks. Repeated course on the recommendation of a doctor.

per 100 g of the drug:

Active substance:

Polymethylsiloxane polyhydrate (product of nonlinear polycondensation of 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate) - 69.90 g.

Excipients:

Purified water - 29.90 g.

Sodium cyclamate (Sweetener E-952) - 0.14 g.

Sodium saccharinate (Sweetener E-954) - 0.06 g.

Children under 1 year of age, individual drug intolerance, intestinal atony, intolerance to sulfa drugs. Pregnancy, lactation

Trade name of the drug. EnterosgelЃ.

International non-proprietary or generic name.
Polymethylsiloxane polyhydrate.

Chemical name. The nonlinear polycondensation product of 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate.

Dosage form. Oral paste, sweet.

Composition:

per 100 g of the drug:

Active substance:

Polymethylsiloxane polyhydrate (product of nonlinear polycondensation of 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate) - 69.90 g.

Excipients:

Purified water - 29.90 g.

Sodium cyclamate (Sweetener E-952) - 0.14 g.

Sodium saccharinate (Sweetener E-954) - 0.06 g.

Description:

Homogeneous pasty mass from white to almost white, odorless.

Pharmacotherapeutic group:

Enterosorbent agent.

Pharmacological properties:

EnterosgelЃ has a porous structure of an organosilicon matrix (molecular sponge) of a hydrophobic nature, which is characterized by a sorption effect in relation to only medium molecular weight toxic metabolites (molecular weight from 70 to 1000). EnterosgelЃ has pronounced sorption and detoxification properties. In the lumen of the gastrointestinal tract, the drug binds and removes from the body endogenous and exogenous toxic substances of various natures, including bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, heavy metal salts, radionuclides, alcohol. The drug also sorbs some metabolic products of the body, including an excess of bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis.EnterosgelЃ does not reduce the absorption of vitamins and microelements, contributes to the restoration of disturbed intestinal microflora and does not affect its motor function.

Pharmacokinetics:

The drug is not absorbed in the gastrointestinal tract, it is excreted unchanged within 12 hours.

Indications for use:

In adults and children, as a detoxifying agent:

• acute and chronic intoxication of various origins;

• acute poisoning with potent and poisonous substances, including drugs and alcohol, alkaloids, heavy metal salts;

• acute intestinal infections of any genesis as part of complex therapy (toxic infections, salmonellosis, dysentery, diarrheal syndrome of non-infectious origin, dysbiosis);

• purulent-septic diseases, accompanied by severe intoxication, as part of complex therapy;

• food and drug allergies;

• hyperbilirubinemia (viral hepatitis) and hyperazotemia (chronic renal failure);

• in order to prevent chronic intoxication for workers in hazardous industries (professional intoxication with chemical agents of polytropic action, xenobiotics, incorporated radionuclides, compounds of lead, mercury, arsenic, oil products, organic solvents, oxides of nitrogen, carbon, fluorides, salts of heavy metals).

Contraindications:

Children under 1 year of age, individual drug intolerance, intestinal atony, intolerance to sulfa drugs.

Pregnancy and lactation:

Contraindicated in pregnancy and lactation.

Method of administration and dosage:

EnterosgelЃ paste is taken orally 1-2 hours before or after meals or other medications, with water.
Dosage for adults - 1 tablespoon (15 g) 3 times a day (45 g).
Dosage for children:

• at the age of 1 to 5 years - 1 teaspoon (5 g) 3 times a day (15 g);

• at the age of 5 to 14 years - 1 dessert spoon (10 g) 3 times a day (30 g).
  For the prevention of chronic intoxication - 30 g per day or in 2 doses of 15 g for 7-10 days monthly.
  In case of severe intoxication during the first three days, the dose of the drug can be doubled.
  The duration of treatment for acute poisoning is 3-5 days, and for chronic intoxications and allergic conditions - 2-3 weeks. Repeated course on the recommendation of a doctor.

Side effect:

Possible nausea, constipation, pruritus, urticaria. With severe renal and / or hepatic insufficiency, aversion to the drug is possible.

Overdose:

No cases of overdose have been identified.

Interaction with other medicinal products:

It is possible to reduce the absorption of other drugs while taking it with EnterosgelЃ.

Special instructions:

The drug can be used in combination therapy with other drugs, subject to the rule of separate administration in time for -1-2 hours before or after taking other drugs.

Storage conditions:

At a temperature not lower than 4 ? C in places inaccessible to children. Protect from drying out after opening the package. Protect from freezing.

Expiration date: 3 years. Do not use after the expiration date printed on the package.

Terms of dispensing from pharmacies: Without prescription.