Enroflon 10% oral 10 ml

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SKU
BIDV1001992
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Enroflon 10% oral 10 ml

DESCRIPTION

Enroflon 10% is a solution for oral administration for the treatment of farm animals, including poultry, for bacterial and mycoplasma diseases. In appearance, Enroflon 10% solution for oral administration is a clear, light yellow liquid.

COMPOSITION

In 1 ml, there are 100 mg of enrofloxacin as an active ingredient, and as auxiliary substances: potassium hydroxide 12.5 and 25 mg, respectively, benzyl alcohol 0.01 ml, Trilon B 10 mg, and purified water to 1 ml.

PHARMACOLOGICAL PROPERTIES

Enroflon 10% solution for oral administration is an antimicrobial drug of the fluoroquinolone group.

Enrofloxacin, which is a part of enroflon, belongs to the group of fluoroquinolones of the 3rd generation, has a wide spectrum of bactericidal action, inhibits the growth and development of most gram-positive and gram-negative microorganisms, including E. coli, Haemophilus, Klebsiella, Pasteurella, Pseudomonas, Bordetella, Campylobacter , Erysipelotrix, Corynebacterium, Staphylococcus, Streptococcus, Actinobacillus, Clostridium, Bacteroides, Fusobacterium, and Mycoplasma spp. Bacterial resistance to enroflon develops relatively slowly, since the mechanism of the antimicrobial action of enrofloxacin is associated with inhibition of the activity of the enzyme gyrase, which affects the replication of the DNA helix in the bacterial cell. The drug is well and quickly absorbed in the gastrointestinal tract and penetrates into all organs and tissues of the body. The maximum concentration of the drug in the blood is achieved within 1-2 hours after the administration of enroflon and remains for 6 hours, and the therapeutic concentration for 24 hours. Enrofloxacin partially undergoes biotransformation, turning into ciprofloxacin. Fluoroquinolones are excreted from the body mainly unchanged in the urine and bile.

Enroflon solution for oral administration, according to the degree of exposure to the body, belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76).

INDICATIONS

Prescribed for therapeutic and therapeutic purposes for colibacillosis; salmonellosis; mycoplasmosis; bronchopneumonia; enteritis; atrophic rhinitis; enzootic pneumonia; mastitis-metritis-agalactia syndrome in pigs; other diseases of calves, lambs, pigs and poultry caused by microorganisms sensitive to fluoroquinolones, as well as for the treatment of atrophic rhinitis, enzootic pneumonia and mastitis-metritis-agalactia syndrome in pigs.

DOSAGE AND APPLICATION

The drug is administered to animals and poultry once a day orally together with water or feed for 3-5 days in the following doses:

Animal species Dose (mg / kg) Solution dose (ml \ 10 kg of feed or water)

Calves 2.5-5 0.25-0.5

Piglets 2.5-5 0.25-0.5

Lambs 2.5-5 0.25-0.5

Broilers, turkeys 2.5-5 0.5

For birds, an enroflon solution is prepared based on the need for water for 1 day. During the treatment period, the bird receives only water containing the drug.

For salmonellosis, Enroflon 5% and 10% solution is used in a two-fold therapeutic dose.

SPECIAL INSTRUCTIONS

The peculiarities of the action during the first use and upon discontinuation of the drug were not revealed.

Slaughter for meat of animals that used enroflon is allowed no earlier than 14 days, poultry - 11 days after stopping the administration of the drug. The meat of animals that were forcedly killed before the expiration of the specified periods can be used for feeding fur animals or for the production of meat and bone meal.

When working with Enroflon oral solution, you should follow the general rules of personal hygiene and safety measures provided for when working with medicinal products.

CONTRAINDICATIONS

It is forbidden to use Enroflon in animals with severe liver and kidney damage, as well as with individual hypersensitivity to fluoroquinolones. During the treatment period, prolonged exposure of animals to direct sunlight should be avoided. It is forbidden to use Enroflon in laying hens, the eggs of which are intended for human consumption, since Enrofloxacin is excreted in the eggs.

The simultaneous use of enroflon with bacteriostatic antibiotics (tetracyclines, macrolides and chloramphenicol), theophylline and steroids is not allowed.

SIDE EFFECTS

When using the drug in accordance with this instruction, side effects and complications, as a rule, are not observed. With increased individual sensitivity of the animal to fluoroquinolones and the occurrence of allergic reactions, the use of Enroflon solution for oral administration is discontinued and antihistamines are prescribed.

SHELF LIFE AND STORAGE

With precautions according to list B. Store the drug in the manufacturer's sealed packaging, in a dry, sun-protected place, out of reach of children. Separated from food and feed at temperatures from 5 to 25 В° C. The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of manufacture.

PACKAGING

Produced in 10 ml glass bottles of appropriate capacity.

Specifications

KolVUP

ten

Manufacturer

VIC

Temperature regime

from +5 to +25

Teaser

for the treatment of farm animals, including poultry for bacterial and mycoplasma diseases

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