Endometramag-Green 1l

DESCRIPTION

Endometramag-Green (Endometramag - Green) - solution for intrauterine administration is used in the complex therapy of endometritis and prevention of postpartum obstetric diseases in cows. In appearance, the drug is a green opalescent liquid. Natural sediment is allowed. Stir before use.

COMPOSITION

Endometramag-Green in 1 ml contains interferon as active ingredients - at least 500,000 (5105) international units (IU), propranolol hydrochloride 15 mg and excipients: propylene glycol, methylcellulose, propylene glycol dicaprylate / dicaprate, tocopherol acetate, chlorophyll, nipagin , nipazol, trilon B, water for injection.

PHARMACOLOGICAL PROPERTIES

Endometramag-Green belongs to the pharmacotherapeutic group of interferons in combinations.

Interferon and propranolol, which are part of the drug, have local and systemic antiviral, immunomodulatory, antiproliferative effects.

The antiviral effect of interferon alpha-2b is mediated by the activation of a number of intracellular enzymes that inhibit viral replication. The immunomodulatory effect is manifested primarily by an increase in the cell-mediated responses of the immune system, which increases the effectiveness of the immune response against viruses and intracellular parasites. The antibacterial effect is mediated by the reactions of the immune system, enhanced by the influence of interferon.

With intrauterine administration, due to the high concentration of interferon in the focus of infection and fixation on the cells of the uterine mucosa, a pronounced local antiviral, antiproliferative effect is achieved, while the systemic effect is insignificant due to the low absorption capacity of the uterine mucosa.

Propranolol hydrochloride is a nonselective beta-blocker that enhances the contractility of the myometrium, which contributes to a faster separation of the placenta and the removal of inflammatory exudate from the uterus.

The drug has no irritating effect on the uterine mucosa and promotes endometrial regeneration.

The components of the drug are poorly absorbed through the mucous membrane of the uterus, which prevents their accumulation in animal products.

In recommended doses, Endometramag-Green is well tolerated by animals, does not have a local irritant, embryotoxic, teratogenic and hepatotoxic effect.

Endometramag-Green, according to the degree of impact on the body, according to the classification of GOST 12.1.007-76, belongs to the 4th hazard class (low-hazard substances).

DOSAGE AND APPLICATION

Before the introduction of the drug, the external genital organs of the cow are sanitized. If necessary, the uterine cavity is freed from inflammatory exudate.

For the treatment of endometritis, Endometramag-GreenВ® is administered intrauterinely at a dose of 50-150 ml per animal using a Janet syringe with an interval of 24-48 hours until clinical recovery. The course of treatment is 3-5 injections. In the treatment of chronic and subclinical endometritis, before the administration of the drug, it is necessary to perform rectal massage of the uterus for 1.5-2.0 minutes.

For the prevention of postpartum diseases after separation of the placenta, abortions or assistance in complicated and pathological childbirth, the drug is administered intrauterinely at a dose of 50-150 ml using a Janet syringe once.

SPECIAL INSTRUCTIONS

When working with Endometramag-Green, you should follow the general rules of personal hygiene and safety measures provided for when working with medicines.

People with hypersensitivity to the drug components should avoid direct contact with Endometramag-Green. Do not drink, smoke or eat while working with the medicinal product. At the end of work, hands should be washed with warm water and soap.

Canisters from under the medicinal product must not be used for domestic purposes, they must be disposed of with household waste.

In case of accidental contact of the drug with the skin or mucous membranes of the eye, they must be rinsed with plenty of water. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have instructions for use of the drug or a label with you).

CONTRAINDICATIONS

Contraindication for the use of the drug is the increased individual sensitivity of the animal to the components of the drug.

It is forbidden to use Endometramag-Green in pregnant cows, it is possible to use the drug in cows during lactation.

SIDE EFFECTS

When using Endometramag-Green in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. With increased individual sensitivity and the manifestation of allergic reactions, the use of the drug is discontinued and the animal is prescribed antihistamines and symptomatic therapy.

SHELF LIFE AND STORAGE

The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 1 year from the date of production, after the first opening of the canister - 14 days. It is prohibited to use the drug after the expiration date. Store the medicinal product in the manufacturer's closed packaging in a place protected from direct sunlight, separately from food and feed, at a temperature of 5 В° C to 25 В° C.

PACKAGING

Endometramag-Green is produced packaged in 1 liter in polyethylene canisters sealed with threaded plastic lids with a first opening control ring. Each consumer package is supplied with instructions for use.

Specifications

Bonus points

0

KolVUP

8

Manufacturer

Mosagrogen

Temperature regime

from +5 to +25

Teaser

used in the complex therapy of endometritis and the prevention of postpartum obstetric diseases in cows