Ekofucin vaginal suppositories 100mg, No. 6

Vaginitis, vulvitis, vulvovaginitis caused by fungi of the genus Candida.

Suppositories, previously released from the contour packaging, are inserted into the vagina, being in the supine position, as deep as possible, 1 time / day at night.

For candidal vaginitis, vulvitis, vulvovaginitis , 1 supp is used intravaginally. within 3-6 days.

With a persistent course of vaginitis caused by Candida albicans , natamycin is additionally prescribed in the form of tablets for oral administration: 1 tab. 4 times / day for 10-20 days to sanitize the focus of candidal infection in the intestine.

The duration of the course of treatment is set individually. After the disappearance of the symptoms of the disease, it is recommended to continue treatment for several more days.

During menstruation, the use of suppositories is interrupted.

1 supp.

Active substance:

Natamycin - 100 mg

Excipients:

lactulose - 300 mg, macrogol glyceryl hydroxystearate - 200 mg, colloidal silicon dioxide - 20 mg, solid fat (Supposir AM) - up to 2300 mg.

Hypersensitivity to the components of the drug.

Description:

Vaginal suppositories from light yellow to light brown, torpedo-shaped; there should be no foreign inclusions on the longitudinal section; the presence of an air rod or funnel-shaped recess is allowed.

Composition:

1 supp.

Active substance:

Natamycin - 100 mg

Excipients:

lactulose - 300 mg, macrogol glyceryl hydroxystearate - 200 mg, colloidal silicon dioxide - 20 mg, solid fat (Supposir AM) - up to 2300 mg.

Clinical and pharmacological group: Drug with antifungal action for local use in gynecology

Pharmaco-therapeutic group: Antifungal agent

pharmachologic effect

Natamycin is an antifungal polyene antibiotic from the macrolide group with a wide spectrum of action. Has a fungicidal effect. It binds to sterols of cell membranes, disrupting their integrity and function, which leads to the death of microorganisms.

It is active against most pathogenic yeast-like fungi (especially Candida albicans), yeast (Torulopsis and Rhodotorula), as well as other pathogenic fungi (Aspergillus, Penicillium). Less active against dermatophytes (Trichophyton, Microsporum, Epidermophyton). Does not affect in vitro gram-positive and gram-negative bacteria.

Resistance to natamycin does not occur in clinical practice.

Pharmacokinetics

EcofucinЃ does not have a systemic effect, because practically not absorbed through intact skin and intact mucous membranes.

Indications

Vaginitis, vulvitis, vulvovaginitis caused by fungi of the genus Candida.

Dosage regimen

Suppositories, previously released from the contour packaging, are inserted into the vagina, being in the supine position, as deep as possible, 1 time / day at night.

For candidal vaginitis, vulvitis, vulvovaginitis , 1 supp is used intravaginally. within 3-6 days.

With a persistent course of vaginitis caused by Candida albicans , natamycin is additionally prescribed in the form of tablets for oral administration: 1 tab. 4 times / day for 10-20 days to sanitize the focus of candidal infection in the intestine.

The duration of the course of treatment is set individually. After the disappearance of the symptoms of the disease, it is recommended to continue treatment for several more days.

During menstruation, the use of suppositories is interrupted.

Side effect

When applied topically, slight irritation and burning sensation at the injection site is possible.

Contraindications for use

Hypersensitivity to the components of the drug.

Application during pregnancy and lactation

It is possible to use the drug EkofucinЃ in pregnant women and during lactation.

special instructions

With vaginal application, under the influence of body temperature, the suppositories turn into a foamy mass, which contributes to the uniform distribution of natamycin over the vaginal mucosa.

During the period of treatment, there is no need to exclude sexual intercourse, however, it is recommended to examine the sexual partners and, if candidal lesions are detected, to conduct a course of treatment with natamycin. During the period of treatment, barrier methods of contraception should be used.

Influence on the ability to drive vehicles and use mechanisms

The use of EkofucinЃ does not affect the ability to drive vehicles and mechanisms.

Overdose

Currently, no cases of an overdose of EkofucinЃ have been reported.

Drug interactions

The drug interaction of EkofucinЃ with other drugs has not been described.

Storage conditions

The drug should be stored in a place protected from moisture and light, out of reach of children, at a temperature not exceeding 25 ? C.

Shelf life

Shelf life is 2 years. Do not use after the expiration date printed on the package.

Terms of sale

The drug is dispensed without a prescription.