each Penzital tab. p / o intestinal. 212.5 mg

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In stock
SKU
OTC102038348
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Category

Enzymes

Scope of the drug

Gastrointestinal tract

Release form

Tablet

Manufacturer country

India

Package quantity, pcs

80

Description

Dosage form

Enteric-coated tablets, white, film

round, biconvex.

Structure

1 tab.

pancreatin 212.5 mg

with enzymatic activity:

amylase 4500 U FIP, lipase 6000 U FIP, protease 300 U FIP

Excipients: lactose, microcrystalline cellulose, sodium starch glycolate, povidone, talc, colloidal silicon dioxide, methacrylic acid copolymer, diethyl phthalate, titanium dioxide.

pharmachologic effect

Enzyme preparation.

Compensates for the lack of exocrine pancreatic function.

The enzymes included in pancreatin (lipase, alpha-amylase, proteases / trypsin, chymotrypsin /) promote the breakdown of proteins to amino acids, fats to glycerol and fatty acids, starch to dextrins and monosaccharides.

The drug improves the functional state of the gastrointestinal tract, normalizes digestion processes.

Trypsin inhibits the stimulated secretion of the pancreas, has an analgesic effect.

Pancreatic enzymes are released from the dosage form in the alkaline medium of the small intestine (since the tablet is coated with an enteric coating, which protects the components of the drug from the effects of gastric juice).

The maximum enzymatic activity is observed 30-45 minutes after taking the drug inside.

Side effects

From the digestive system: diarrhea, constipation, a feeling of discomfort in the stomach, nausea (however, the causal relationship of these side effects with taking the drug has not been established, since these reactions refer to symptoms of exocrine pancreatic insufficiency).

Others: allergic reactions.

It should be borne in mind that with prolonged use of the drug in high doses, the development of hyperuricosuria, hyperuricemia is possible.

With cystic fibrosis, if the recommended dose is exceeded, strictures (fibrous colonopathy) may develop in the ileocecal section in the ascending colon.

When using pancreatin in high doses in children, perianal irritation and irritation of the oral mucosa may occur.

Selling features

Available without a prescription

Special conditions

In case of cystic fibrosis, the use of the drug in high doses is not recommended due to the risk of developing fibrous colonopathy.

The dose of the drug should be adequate to the amount of enzymes that is necessary for the absorption of fats, taking into account the quality and quantity of food consumed.

With prolonged use of Penzital, iron supplements should be prescribed simultaneously.

Overdose

Symptoms: hyperuricosuria, hyperuricemia, constipation in children.

Treatment: it is necessary to cancel the drug and prescribe symptomatic therapy.

Indications

- replacement therapy for exocrine pancreatic insufficiency (chronic pancreatitis, conditions after pancreatectomy, after irradiation, dyspepsia, Remheld syndrome / gastrocardiac syndrome /, cystic fibrosis, flatulence, diarrhea of ​​non-infectious origin)

- violations of food assimilation (conditions after resection of the stomach or small intestine)

- to improve the digestion of food for people with normal gastrointestinal tract function in case of errors in nutrition (eating fatty foods, irregular eating, eating a large amount of food) and with violations of chewing function, a sedentary lifestyle, prolonged immobilization

- preparation for X-ray examination and ultrasound of the abdominal organs.

Contraindications

- acute pancreatitis

- exacerbation of chronic pancreatitis

- hypersensitivity to drug components.

Application during pregnancy and lactation

The safety of using Penzital during pregnancy has not been studied enough.

Therefore, the use of the drug is possible in cases where the expected benefit to the mother outweighs the potential risk to the fetus.

Drug interactions

With the simultaneous use of pankr

Name ENG

PENZITAL

Clinical and pharmacological group

Enzyme preparation

ATX code

Multienzymes (lipase, protease etc.)

Dosage

212.5mg

Structure

1 tab.

pancreatin 212.5 mg.

with enzymatic activity: amylase 4500 U FIP, lipase 6000 U FIP, proteases 300 U FIP.

Excipients: lactose, microcrystalline cellulose, sodium starch glycolate, povidone, talc, colloidal silicon dioxide, methacrylic acid copolymer, diethyl phthalate, titanium dioxide.

Indications

Replacement therapy for exocrine pancreatic insufficiency (chronic pancreatitis, pancreatectomy, condition after irradiation, dyspepsia, Remheld's syndrome (gastrocardial syndrome), cystic fibrosis)

flatulence, diarrhea of ​​non-infectious genesis

violation of food assimilation (condition after resection of the stomach and small intestine)

to improve the digestion of food in persons with normal gastrointestinal tract function in case of errors in nutrition (consumption of fatty foods, large amounts of food, irregular nutrition) and in case of impaired chewing function, sedentary lifestyle, prolonged immobilization

preparation for X-ray examination and ultrasound of the abdominal organs.

Storage conditions and periods

In a dry place at a temperature of 2-25 degrees.

Expiration date: 3 years

INN / Active ingredient

pancreatin

Contraindications

Hypersensitivity to drug components

acute pancreatitis

exacerbation of chronic pancreatitis.

Specifications

Category

Enzymes

Scope of the drug

Gastrointestinal tract

Release form

Tablet

Manufacturer country

India

Package quantity, pcs

80

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Shreya Life Sciences

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Cell-free contoured packaging (strip)

Type of consumer packaging

Cardboard box

Pharmaco-therapeutic group

Digestive Enzyme Remedy

Anatomical and therapeutic characteristics

A09AA02 Polyenzyme preparations (lipase + protease, etc.)

Dosage form

Enteric-coated tablets

The target audience

Children

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

pancreatin 212.5 mg

Package weight, g

45

Mode of application

:

The drug should be taken orally during or after a meal, the tablets are not chewed and washed down with a non-alkaline liquid (water, fruit juices).

< br> The dose is determined individually, depending on the degree of indigestion.

< br> For adults, the drug is prescribed for 1-2 tablets.

3 times / day

< br> For children, the dose is determined individually.

< br> The duration of treatment can vary from several days (if the digestion process is disturbed due to dietary errors) to several months and years (if constant substitution therapy is necessary).

Information on technical characteristics, delivery set, country of manufacture

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