Drotaverine | Drotaverin-Teva tablets 40 mg 40 pcs.

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BID885770
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Pharmacological action

Drotaverinum - myotropic antispasmodic. In chemical structure and pharmacological properties it is close to papaverine, but has a stronger and longer lasting effect.

Reduces the flow of ionized calcium into smooth muscle cells by inhibiting phosphodiesterase and intracellular cAMP accumulation.

It has a pronounced and lasting effect on the smooth muscles of internal organs and blood vessels.

Expands blood vessels, causes a moderate decrease in blood pressure, increases cardiac output, has some antiarrhythmic effect.

Reduces the tone of cerebral vessels and increases their blood supply.

Virtually no effect on the autonomic nervous system and does not penetrate the central nervous system.

Drotaverinum has no anticholinergic effect, therefore, unlike anticholinergic antispasmodics, it can be used in patients with glaucoma.
Pharmacological action

Drotaverinum - myotropic antispasmodic. In chemical structure and pharmacological properties it is close to papaverine, but has a stronger and longer lasting effect.

Reduces the flow of ionized calcium into smooth muscle cells by inhibiting phosphodiesterase and intracellular cAMP accumulation.

It has a pronounced and lasting effect on the smooth muscles of internal organs and blood vessels.

Expands blood vessels, causes a moderate decrease in blood pressure, increases cardiac output, has some antiarrhythmic effect.

Reduces the tone of cerebral vessels and increases their blood supply.

Virtually no effect on the autonomic nervous system and does not penetrate the central nervous system.

Drotaverinum has no anticholinergic effect, therefore, unlike anticholinergic antispasmodics, it can be used in patients with glaucoma.

Indications

spasm of smooth muscles of internal organs (cardio- and pylorospasm),

chronic gastroduodenitis,

gastric and duodenal ulcer,

gallstone disease, chronic cholelithiasis, chronic cholecystomy spastic intestinal dyskinesia,

intestinal colic due to gas retention after surgery,

colitis,

proctitis,

tenesmus,

flatulence,

urolithiasis (renal colic),

pyelitis,

spasm of cerebral vessels, coronary and peripheral arteries, the need to weaken uterine contractions and relieve cervical spasm during childbirth,

smooth muscle spasm during instrumental interventions,

dysmenorrhea,

strong labor pains.

Drotaverinum hydrochloride can also be used as an adjunct in hypertensive crises.

Contraindications

hypersensitivity to the active substance (drotaverine hydrochloride) or to any of the auxiliary components

severe hepatic or renal failure,

severe heart failure (low cardiac output syndrome),

AV blockade of cardiomyopathy II and III degree,

arterial hypotension,

children under 12 years of age.

Use during pregnancy and lactation

Use with caution in pregnancy and lactation (breastfeeding).

Special instructions

Caution should be exercised when using Drotaverin-Teva in patients with arterial hypotension.

The composition of the tablets includes lactose, therefore, the drug Drotaverin-Teva is not prescribed for patients with lactose intolerance, lactase deficiency, glucose-galactose malabsorption syndrome.

Impact on the ability to drive transp. Wed and fur .: When administered in therapeutic doses, the drug Drotaverin-Teva does not affect the ability to engage in potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Composition

1 tablet contains:

Active ingredient: drotaverine hydrochloride 40 mg.

Excipients: potato starch 30.71 mg, lactose monohydrate 57 mg, crospovidone (Polyplasdone XL-10) 2.923 mg, povidone (low molecular weight polyvinylpyrrolidone) 5.847 mg, talc 2.05 mg, magnesium stearate 1.47 mg.

Dosage and administration

Inside, with plenty of fluids.

The recommended daily intake for adults is 120-240 mg (in 2–3 doses).

For children aged 6 to 12 years, the maximum daily dose is 80 mg, divided into 2 doses for children over 12 years of age, the maximum daily dose is 160 mg, divided into 2-4 doses.

Recommended duration of treatment without medical advice is 1-2 days.

Side effects

Side effects are classified according to the following frequency: very often - at least 10% often - at least 1%, but less than 10% infrequently - at least 0.1%, but less than 1% rarely - at least 0 , 01%, but less than 0.1% is very rare (including individual reports) - less than 0.01% the frequency is unknown - there is insufficient data to estimate the frequency of the phenomenon in the population.

From the gastrointestinal tract: rarely - nausea, constipation.

From the central nervous system: rarely - headache, dizziness, insomnia.

From the cardiovascular system: rarely - heart palpitations very rarely - lowering blood pressure.

Drug Interactions

With the simultaneous use of drotaverine, the antiparkinsonian effect of levodopa may be reduced.

With simultaneous use with papaverine, bendazole, an increase in antispasmodic action is possible.

Overdose

There is no evidence of an overdose of Drotaverin-Teva.

Overdose symptoms may include cardiac arrhythmias and conduction disturbances (including complete blockade of the bundle of His bundle), cardiac arrest, even death.

Treatment: gastric lavage, symptomatic therapy.

Storage conditions

Store at a temperature not exceeding 25 РC.

Keep out of the reach of children!

The Expiration of

is 3 years.

Deystvuyuschee substances

Drotaverine

Pharmacy holidays

Over the counter

Form of Treatment

tablets

Appointment

Adult prescribing, Children prescribing doctor, Pregnant prescribing pfroaf51660 doctor's appointments, Nursing moms, Adult

Indications

From urolithiasis, Cystitis, From cholecystitis, From cholecystitis, From cholecystitis, From odenitis, From colitis, From stomach and duodenal ulcers, From a threatening miscarriage, From cholelithiasis

Possible product names

Drotaverin-Teva tablets 40 mg 40 pcs.

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