Domperidone | Domperidone-Teva tablets 10 mg 30 pcs.

Special Price $11.90 Regular Price $24.00
In stock
Latin name

Latin name


Release form

Domperidon-Teva. Film-coated tablets.

packaging 30 pcs

ДомпРридон-ТРва - противорвотноРсрРдство. Оказ ваРт противорвотноРдРйствиР, успокаиваРт икоту и устраняРт в нРкотор х случаях тошноту. ДРйствиРобусловлРно блокадой цРнтральн х допаминов х рРцРпторов. Благодаря этому устраняРтся ингибирующРРвлияниРдопамина на моторную функцию ЖКТ и пов шаРтся эвакуаторная и двигатРльная активность жРлудка.


Абсорбция послРприРма внутрь, натощак - б страя (приРм послРРд ,снижРнная кислотность жРлудочного сока замРдляют и умРньшают абсорбцию). Cmax достигаРтся чРрРз 1 ч. Биодоступность составляРт 15% (эффРкт пРрвого прохождРния чРрРз пРчРнь). Связ ваниРс бРлками плазм - 90%. ПроникаРт в различн Рткани, плохо проходит чРрРз ГЭБ. МРтаболизируРтся в пРчРни и в стРнкРкишРчника (путРм гидроксилирования и N-дРзалкилирования). водится чРрРз кишРчник 66%, почками - 33%, в т.ч. в нРизмРнРнном видР- 10% и 1%, соотвРтствРнно. T1/2 - 7-9 ч, при в ражРнной ХПН - удлиняРтся.


Nausea, vomiting, hiccups of various origins (with toxemia, radiation therapy, dietary disorders, taking certain medications / morphine /, endoscopic and radiopaque studies, in the postoperative period).

Postoperative hypotension and atony of the stomach and intestines, biliary dyskinesia, flatulence, reflux esophagitis, cholecystitis, cholangitis, various types of dyspepsia.

Nausea and vomiting caused by dopaminomimetics.


Gastrointestinal bleeding, mechanical intestinal obstruction, perforation of the stomach or intestines, prolactinoma, children under 1 year of age (up to 5 years and for children weighing up to 20 kg - for tablets), hypersensitivity to domperidone, pregnancy, lactation (breastfeeding).

Pregnancy and lactation

There is insufficient data on the use of domperidone during pregnancy. To date, there is no evidence of an increased risk of malformations in humans. However, domperidone should be prescribed during pregnancy only if its use is justified by the expected therapeutic benefit for the mother and minimal risk to the fetus.

In women, the concentration of domperidone in breast milk is from 10 to 50% of the corresponding plasma concentration and does not exceed 10 ng / ml. The total amount of domperidone excreted in breast milk is less than 7 mcg per day when using the maximum allowable doses of domperidone. It is not known whether this concentration has a negative effect on infants. In this regard, when using domperidone during lactation, breast-feeding should be stopped.


1 tablet contains:

Active ingredient: domperidone 10 mg

Excipients: microcrystalline cellulose - 60.00 mg, pregelatinized starch - 19.46 mg, colloidal silicon dioxide (aerosil) - 0.09 mg, magnesium 0.45 mg, polyvinyl alcohol - 1.44 mg, macrogol (polyethylene glycol) - 0.73 mg, talc - 0, 53 mg, titanium dioxide - 0.90 mg.

Dosage and administration

Inside before meals, drinking plenty of water.

Adults and children weighing more than 35 kg 1-2 tablets 3-4 times a day. The maximum dose is 80 mg per day. Duration of admission is 4 weeks. Further administration of the drug is possible after consultation with a doctor.

Patients with renal failure are recommended to reduce the frequency of taking the drug to 1-2 times a day.

Side effects of the

Digestive system: Gastrointestinal upset (transient intestinal cramps).

From the nervous system: extrapyramidal disorders (in children and in persons with increased BBB permeability, in adults - isolated cases) these phenomena are completely reversible and disappear after stopping the drug.

Allergic reactions: skin rash, urticaria.

Other: hyperprolactinemia (galactorrhea, gynecomastia, amenorrhea).

Drug interaction

Cimetidine, sodium bicarbonate reduce the bioavailability of domperidone.

M-cholin blockers and antacid drugs neutralize the action of domperidone.

Increase the concentration of domperidone in plasma CYP3A4 isoenzyme inhibitors: antifungal drugs of the azole series, macrolide antibiotics, HIV protease inhibitors, nefazodone (antidepressant). Co-administration with ketoconazole results in an approximately threefold increase in the maximum concentration of domperidone.

Concurrent administration with paracetamol and digoxin had no effect on the concentration of these drugs in the blood.

Compatible with antipsychotic drugs (neuroleptics) and dopaminergic receptor agonists (bromocriptine, levodopa).


Symptoms: drowsiness, disorientation, extrapyramidal disorders (especially in children).

Treatment: administration of activated charcoal, with extrapyramidal disorders -

m-cholin blockers, antiparkinsonian drugs or antihistamines with anticholinergic properties.

Storage conditions

In a dry, dark place at a temperature of no higher than 25 РC.

Shelf suitability

3 Year

Active ingredient


dosage form

Dosage form


Teva Pharmaceutical Enterprises Co., Ltd., Israel

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