Dolgit gel 5%, 50 g
Expiration Date: 05/2027
Russian Pharmacy name:
Долгит гель 5%, 50 г
Apply externally. Apply to the affected area 2-3 times / day.
1 g
ibuprofen 50 mg
Hypersensitivity to ibuprofen;
'aspirin triad' (including history);
violation of the integrity of the skin at the site of application (including infected wounds and abrasions, weeping dermatitis, eczema);
children up to age 14;
pregnancy, lactation.
With caution In the presence of concomitant diseases of the liver and kidneys, gastrointestinal tract, exacerbation of hepatic porphyria, with bronchial asthma, urticaria, rhinitis, polyps of the nasal mucosa, chronic heart failure, as well as elderly patients.
pharmachologic effect
NSAIDs, a derivative of phenylpropionic acid. When applied externally, it has anti-inflammatory and analgesic effects. Reduces morning stiffness, increases the range of motion in the joints. The mechanism of action is associated with inhibition of the activity of COX, the main enzyme of the metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever. The analgesic effect is due to both a peripheral (indirectly, through suppression of prostaglandin synthesis) and a central mechanism (inhibition of prostaglandin synthesis in the central and peripheral nervous system).
Side effect
Local reactions: when applied externally, skin hyperemia, a burning sensation or tingling sensation are possible.
Application during pregnancy and lactation
Use during pregnancy and breastfeeding is contraindicated.
Application for violations of liver function
Contraindicated in severe liver dysfunction. Use with caution in case of concomitant liver diseases.
Application for impaired renal function
Contraindicated in severe renal impairment. Use with caution in case of concomitant kidney disease.
Application in children
Ibuprofen is contraindicated for external use in children under the age of 14.
Use in elderly patients
Use with caution in elderly patients.
special instructions
When applied externally, avoid contact with eyes and lips. Do not apply under an occlusive (airtight) dressing. Avoid direct sunlight on the area of ??application.
Drug interactions
Theoretically, with simultaneous use with other NSAIDs, side effects may increase.