Dironet suspension for dogs 10ml
DESCRIPTION
Dironet is a suspension for oral administration for nematodes and cestodes in dogs. In appearance, the drug is a yellow suspension. During storage, stratification of the suspension is allowed, which disappears when shaken.
COMPOSITION
Dironet suspension in 1 ml contains as active ingredients: pyrantela pamoat - 15 mg, praziquantel - 5 mg and ivermectin - 0.006 mg and excipients - nipagin - 0.1 mg, nipazole - 0.05 mg, tween-80 - 20, 0 mg, lactose - 300.0 mg, distilled water - up to 1 ml.
PHARMACOLOGICAL PROPERTIES
Dironet has a wide spectrum of action at all stages of development of round and tape helminths, incl. Toxocara canis, Toxocara cati, Toxascaris leonina, Uncinaria stenocephala, Ancylostoma caninum, Trichuris vulpis, Echinococcus granulosus, Echinococcus multilocularis, Diphyllobothrium latum, Dipylidium caninum, Multicepsia multiceps. other. The drug has a detrimental effect on microfilariae Dirofilaria immitis and D. repens in carnivores, and also prevents the development of microfilariae.
The mechanism of action of ivermectin is to bind to glutamate-dependent chlorine channels located mainly in the swallowing and somatic muscles. As a result, the permeability of the membrane to chlorine ions increases, the transmission of neuromuscular impulses is blocked, paralysis and death of the parasite occurs.
The mechanism of action of pyrantel pamoate is to block neuromuscular transmission, impair the permeability of cell membranes and inhibition of cholinesterase, which also leads to paralysis and death of the parasite.
The mechanism of action of praziquantel is based on impaired glucose transport and microtubular function in cestodes, inhibition of fumarate reductase activity and ATP synthesis, increased permeability of cell membranes and impaired muscle innervation.
INDICATIONS
Dironet suspension is used in dogs for the treatment and prevention of nematodes of the gastrointestinal tract (toxocariasis, toxascariosis, uncinariosis, ankylostomiasis, trichocephalosis) and cestodoses (teniasis, dipyldiosis, echinococcosis, diphyllobothriosis, and mesocystrophytosis.
DOSAGE AND APPLICATION
Dironet suspension is applied to animals with nematodes and cestodoses once, individually in the morning feeding with a small amount of feed or injected forcibly using a dispenser at the rate of 1 ml of suspension per 1 kg of animal weight.
Shake the container with the suspension thoroughly before use.
A special diet and the use of laxatives before deworming are not required.
When deworming animals weighing less than 0.5 kg, immediately before use, 0.3 ml of boiled water is added to the measured dose of the suspension, shaken thoroughly and injected into the animal.
For prophylactic purposes, animals are dewormed in a therapeutic dose on a quarterly basis, as well as before each vaccination.
To stop microfilariaemia in dogs infested with Dirofilaria immitis or Dirofilaria repens, the drug is prescribed in a therapeutic dose once, once a month.
In order to prevent dirofilariasis in regions unfavorable for the disease, Dironet suspension is used in the spring-summer-autumn period: once before the start of mosquito flight (March-April), then monthly during the entire period from April to October and the last time in the season 1 month after the end of the flight of mosquitoes (October-November).
CONTRAINDICATIONS
Do not use the drug in conjunction with piperazine derivatives, as well as pregnant and lactating animals, kittens up to three weeks of age.
SIDE EFFECTS
When using the drug according to the instructions, side effects and complications are not observed.
SHELF LIFE AND STORAGE
Store Dironet suspension in the manufacturer's closed packaging, protected from light and moisture, separately from food and feed at a temperature of 0 В° C to 20 В° C.
The shelf life of the medicinal product, subject to storage conditions, is 1 year from the date of production.
PACKAGING
The drug is produced packaged in 10 ml in polymer bottles with a syringe-dispenser.
Specifications
KolVUP
80
Manufacturer
Agrovetzashita
Temperature regime
from 0 to +20
Teaser
comprehensive broad-spectrum anthelmintic drug for dogs