Dirofen suspension 60 for adult dogs and cats 10ml
DESCRIPTION
Dirofen-suspension 60 (Dirofen-suspension 60) - suspension for oral administration for adult dogs and cats. In appearance, the drug is a suspension from light yellow to dark yellow in color with particles uniformly distributed in it. During storage, separation of the suspension is allowed, which disappears after shaking.
COMPOSITION
Containing in 1 ml as active ingredients, respectively: pyrantel pamoate - 45 mg and praziquantel - 15 mg, and also auxiliary substances: oil, glycerin, aspaqvit C 200, 11 sorbate-8O each, sucralose, xantha gum, Na-carboxymethyl cellulose, sodium benzoate, potassium sorbate, 20% polydimethylsiloxane emulsion, purified water.
PHARMACOLOGICAL PROPERTIES
Dirofen suspension 60 belongs to the group of anthelmintic drugs in combination.
The combination of praziquantel and pyrantel pamoate, which are part of the drug, has a wide spectrum of anthelmintic action on all phases of the development of round and tapeworms parasitizing in dogs, cats, ferrets (Toxocara canis, Toxocara mystax, Toxascaris leonina, Tacinloceinaria cantenloceinium , Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps) and in ornamental rodents (Syphacia obvelata, Syphacia muris, Aspiculina tetraptera, Rodentadentisolepis)
Pyrantela pamoat is a compound of the pyrimidine group, active against sexually mature and immature nematodes, its mechanism of action is based on blocking the transmission of nerve impulses in neuromuscular synapses by depolarizing the membranes of muscle cells, which causes paralysis of the muscular system of nematodes; pyrantel is poorly absorbed, which ensures its prolonged action on helminths in the intestine; excreted from the body mostly unchanged (93%) with feces.
Praziquantel is a compound of the pyrazinisoquinoline group, which is active against sexually mature and immature cestodes; the mechanism of its action is based on inducing the breakdown of tegument and inhibition of fumarate reductase, persistent depolarization of muscle cells of the helminth, disruption of energy metabolism, which causes paralysis and death of cestodes and promotes their excretion from the gastrointestinal tract. Praziquantel is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, and is distributed in the organs and tissues of the animal; binds to serum proteins of the blood (70-80%), partially metabolized in the liver, re-excreted into the intestine, excreted from the body mainly in the urine (up to 80%).
Dirofen suspension 60 according to the degree of impact on the body belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-7 6), in recommended doses it does not have embryotoxic, teratogenic and sensitizing effects. Well tolerated by dogs and cats of different breeds and ages, ferrets and decorative rodents.
INDICATIONS
Dirofen suspension 60 is prescribed for adult dogs and cats with prophylactic and therapeutic purposes for nematodes (toxocariasis, toxascariasis, uncinariosis, ankylostomiasis), cestodosis (teniidosis, dipylidiosis, echinococcosis, diphyllobothriosis, mesocestoidosis) and mixed cestodosis.
DOSES AND METHOD OF APPLICATION
Dirofen suspension 60 is administered to animals orally individually, once, in the morning feeding with a small amount of food or injected forcibly onto the root of the tongue using a syringe dispenser in the following doses: adult dogs and cats - 1 ml of DirofenВ® suspension 60 per 3 kg of animal weight ...
No prior fasting diet or laxatives are required.
With a strong degree of invasion, deworming is recommended to be repeated after 1O days.
For prophylactic purposes, deworming is carried out once every 3 months, and then before each vaccination.
SIDE EFFECTS
When using Dirofen suspension 60 in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. With increased individual sensitivity to the components of the drug and the appearance of side effects and complications, the use of the drug is discontinued and desensitizing therapy is carried out.
CONTRAINDICATIONS
A contraindication to use is an individual intolerance to the components of the drug (including a history).
Dirofen suspension 60 should not be used in depleted animals, patients with infectious diseases and recovering animals.
SPECIAL INSTRUCTIONS
When used in accordance with the instructions, no special instructions are required.
SHELF LIFE AND STORAGE
Store the drug in the manufacturer's sealed packaging, protected from direct sunlight, separately from food and feed, at a temperature from 0 В° C to 25 В° C.
The shelf life of the medicinal product, subject to storage conditions in the manufacturer's sealed packaging, is 2 years from the date of production, after opening the bottle - 90 days.
PACKAGING
The drug is produced packaged in 10 ml bottles made of polymeric materials, sealed with screw caps and packed individually in cardboard boxes, complete with instructions for use, a syringe-dispenser and stickers in the veterinary passport.
Specifications
Bonus points
0
KolVUP
6
Manufacturer
APICENNA
Temperature regime
from 0 to +25
Teaser
broad-spectrum anthelmintic drug