Dirofen-paste 60 for adult dogs and cats 10ml

DESCRIPTION

Dirofen-pasta 60 (Dirophen-pasta 60) - a paste for oral use for deworming adult dogs and cats. In appearance, the drug is a paste with a creamy consistency of light yellow color.

COMPOSITION

In 1 ml as active ingredients, respectively: pyrantel pamoat - 45 mg and praziquantel - 15 mg, as well as auxiliary substances: pumpkin seed oil - 5 mg, tween-80 - 5 mg, cyclamate saccharin and aspartame - 0.5 mg each, sodium benzoate - 1.5 mg, Na-carboxymethyl cellulose - 15 mg and distilled water - up to 1 ml.

PHARMACOLOGICAL PROPERTIES

Dirofen-paste and 60 belongs to the pharmacotherapeutic group: anthelmintic agents in combinations.

The combination of pyrantel and praziquantel pamoate, which is part of the drug, has a wide spectrum of anthelmintic action on all phases of development of round and tape helminths parasitizing in dogs, cats, ferrets (Toxocara canis, Toxocara mystax, Toxascaris leonina, Taenoma sialocephalus, Uncininaria Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps) and in ornamental rodents (Syphacia obvelata, Syphacia muris, Aspicul tetraptera, Rodenta nuropis stramolepine)

Pyrantela pamoat is a compound of the pyrimidine group, active against sexually mature and immature nematodes, its mechanism of action is based on blocking the transmission of nerve impulses in neuromuscular synapses by depolarizing the membranes of muscle cells, which causes paralysis of the muscular system of nematodes; pyrantel is poorly absorbed, which ensures its prolonged action on helminths in the intestine; excreted from the body mostly unchanged (93%) with feces.

Praziquantel is a compound of the group of pyrazinisoquinolines, active against sexually mature and immature cestodes; the mechanism of its action is based on inducing the breakdown of tegument and inhibition of fumarate reductase, persistent depolarization of muscle cells of the helminth, disruption of energy metabolism, which causes paralysis and death of cestodes and promotes their excretion from the gastrointestinal tract. Praziquantel is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, and is distributed in the organs and tissues of the animal; binds to serum proteins of the blood (70-80%), partially metabolized in the liver, re-excreted into the intestine, excreted from the body mainly in the urine (up to 80%).

Dirofen-paste 60 in terms of the degree of impact on the body belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have embryotoxic, teratogenic and sensitizing effects. Well tolerated by dogs and cats of different breeds and ages, ferrets and rodents.

INDICATIONS

Dirofen paste 60 - for adult dogs and cats, with a prophylactic and therapeutic purpose for nematodes (toxocariasis, toxascariasis, uncinariosis, ankylostomiasis), cestodosis (teniidosis, dipylidiosis, echinococcosis, diphyllobothriasis, mesocestoidal nematosis)

DOSES AND METHOD OF APPLICATION

Dirofen-paste is administered to the animals once individually in the morning feeding with a small amount of food or injected or injected into the oral cavity, squeezing the paste out of the syringe-dispenser for adult dogs and cats - 1 ml of Dirofen-paste 60 per 3 kg of animal weight. A preliminary fasting diet and the use of laxatives are not required when using the drug.

For prophylactic purposes, deworming is carried out every 3 months, as well as before each vaccination. Therapeutic measures against nematodes and cestodes are carried out according to indications. With a strong degree of invasion, the paste is re-set after 10 days. For pregnant females, the drug is prescribed 3 weeks before the expected birth with caution, under the supervision of a veterinarian, for lactating females - 2 - 3 weeks after birth.

SPECIAL INSTRUCTIONS

When used in accordance with the instructions, no special instructions are required.

With a significant overdose, the animal may experience a depression, refusal to feed, excessive salivation, and gastrointestinal disorders. In these cases, general measures are used to remove the drug from the body.

Dirofen paste 60 should not be used concomitantly with piperazine and cholinesterase inhibitors.

Violations of the recommended timing for deworming animals should be avoided, as this can lead to a decrease in effectiveness. If the next deworming is missed, the use of Dirofen-paste 60 is resumed in the same dose, according to the same scheme.

Dirofen Paste 60 is not intended for use in productive animals.

SIDE EFFECTS

When using Dirofen-paste 60 in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. With increased individual sensitivity to the components of the drug and the appearance of side effects and complications, the use of the drug is discontinued and desensitizing therapy is carried out.

CONTRAINDICATIONS

Increased individual sensitivity to drug components. It is not recommended to deworm females in the first half of pregnancy and within 3 weeks after childbirth, puppies under 3 weeks of age, as well as patients with infectious diseases, convalescent and malnourished animals. Do not prescribe the paste simultaneously with piperazine derivatives and other drugs that inhibit cholinesterase.

SHELF LIFE AND STORAGE

Store the drug in the manufacturer's sealed packaging, in a dry, dark place, separate from food and feed, at a temperature from 0 В° C to 25 В° C.

Shelf life, subject to storage conditions, is 2 years from the date of production.

PACKAGING

Packaged in 10 ml polymeric syringes-dispensers with stickers for a veterinary passport, which are packed in cardboard boxes.

Specifications

Bonus points

0

KolVUP

6

Manufacturer

APICENNA

Temperature regime

from 0 to +25

Teaser

for deworming adult dogs and cats