Dirofen paste 20 for kittens and puppies 10ml

DESCRIPTION

Dirofen-paste 20 for kittens and puppies is a broad-spectrum anthelmintic drug. In appearance, the drug is a paste of a greasy consistency of light yellow color.

COMPOSITION

In 1 ml, pyrantel pamoat - 15 mg and praziquantel -5 mg, respectively, as active ingredients, as well as auxiliary substances: pumpkin seed oil - 5 mg, tween-80 - 5 mg, cyclamate saccharin and aspartame - 0.5 mg each, sodium benzoate - 1.5 mg, Na-carboxymethyl cellulose - 15 mg and distilled water - up to 1 ml.

PHARMACOLOGICAL PROPERTIES

DirofenВ®-paste 20 belongs to the pharmacotherapeutic group: anthelmintic agents in combinations.

The combination of pyrantel and praziquantel pamoate, which is part of the drug, has a wide spectrum of anthelmintic action on all phases of development of round and tape helminths parasitizing in dogs, cats, ferrets (Toxocara canis, Toxocara mystax, Toxascaris leonina, Taenoma sialocephalus, Uncininaria Echinococcus granulosus, Alveococcus multilocularis, Mesocestoides lineatus, Dipylidium caninum, Diphyllobothrium latum, Multiceps multiceps) and in ornamental rodents (Syphacia obvelata, Syphacia muris, Aspicul tetraptera, Rodenta nuropis stramolepine)

Pyrantela pamoat is a compound of the pyrimidine group, active against sexually mature and immature nematodes, its mechanism of action is based on blocking the transmission of nerve impulses in neuromuscular synapses by depolarizing the membranes of muscle cells, which causes paralysis of the muscular system of nematodes; pyrantel is poorly absorbed, which ensures its prolonged action on helminths in the intestine; excreted from the body mostly unchanged (93%) with feces.

Praziquantel is a compound of the group of pyrazinisoquinolines, active against sexually mature and immature cestodes; the mechanism of its action is based on inducing the breakdown of tegument and inhibition of fumarate reductase, persistent depolarization of muscle cells of the helminth, disruption of energy metabolism, which causes paralysis and death of cestodes and promotes their excretion from the gastrointestinal tract. Praziquantel is rapidly absorbed in the gastrointestinal tract, reaching a maximum concentration in blood plasma after 1-3 hours, and is distributed in the organs and tissues of the animal; binds to serum proteins of the blood (70-80%), partially metabolized in the liver, re-excreted into the intestine, excreted from the body mainly in the urine (up to 80%).

Dirofen-paste 60 in terms of the degree of impact on the body belongs to low-hazard substances (hazard class 4 according to GOST 12.1.007-76), in recommended doses it does not have embryotoxic, teratogenic and sensitizing effects. Well tolerated by dogs and cats of different breeds and ages, ferrets and rodents.

DOSAGE AND APPLICATION

DirofenВ®-paste 20 is prescribed for kittens and puppies from 3 weeks of age, ferrets and ornamental rodents from 3-4 weeks of age with a preventive and therapeutic purpose for nematodes (toxocariasis, toxascariasis, uncinariosis, ankylostomiasis), cestodosis (teniidosis, echipylidiosis , diphyllobothriasis, mesocestoidosis) and mixed nematodo-cestoid invasions.

Dirofen-paste 20 is applied to animals individually, once, in the morning feeding with a small amount of food, or is injected forcibly onto the root of the tongue using a syringe-dispenser in the following dose for adult cats, puppies, kittens, ferrets and decorative rodents - 1 ml of Dirofen-paste 20 per 1 kg of animal weight.

For pregnant bitches and cats, the drug is prescribed 3 weeks before the expected birth with caution, under the supervision of a veterinarian, lactating females - 2-3 weeks after birth.

No prior fasting diet or laxatives are required.

With a strong degree of invasion, deworming is recommended to be repeated after 10 days.

For prophylactic purposes, deworming is carried out in a therapeutic dose once every 3 months, as well as before each vaccination.

SPECIAL INSTRUCTIONS

With a significant overdose, the animal may experience a depression, refusal to feed, excessive salivation, and gastrointestinal disorders. In these cases, general measures are used to remove the drug from the body.

The drug is intended for single use.

CONTRAINDICATIONS

A contraindication to the use of the drug is an individual intolerance to the components of the drug (including a history).

Dirofen-paste 20 should not be used in malnourished, sick with infectious diseases and recovering animals.

SIDE EFFECTS

When using Dirofen-paste 20 in accordance with this instruction, side effects and complications in animals, as a rule, are not observed.

With increased individual sensitivity to the components of the drug and the appearance of allergic reactions, its use is discontinued and antihistamines and symptomatic therapy are prescribed to the animal.

PERSONAL PREVENTION MEASURES

When working with Dirofen-paste 20, you should follow the general rules of personal hygiene and safety measures provided for when working with medicines. While working with the medicinal product, it is not allowed to smoke, drink or eat. After finishing work, wash your hands with warm water and soap.

In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of water. People with hypersensitivity to the components of the drug should avoid direct contact with Dirofen-paste 20. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (with you have instructions for use of the drug or a label).

SHELF LIFE AND STORAGE

Store the drug in the manufacturer's sealed packaging, in a dry, dark place, separate from food and feed, at a temperature from 0 В° C to 25 В° C.

Shelf life, subject to storage conditions, is 2 years from the date of production. It is forbidden to use Dirofen-paste 20 after the expiration date.

PACKAGING

Dirofen-paste 20 is produced in polymer syringes-dispensers, individually packed in cardboard boxes of 6 ml.

Specifications

Bonus points

0

KolVUP

6

Manufacturer

APICENNA

Temperature regime

from 0 to +25

Teaser

broad-spectrum anthelmintic drug