Dimexide concentrate for prig. solution for d / nar. approx., 100ml

• Rheumatoid arthritis,

• ankylosing spondylitis,

• deforming osteoarthritis,

• scleroderma,

• erythema nodosum;

• bruises

• sprains,

• traumatic infiltrates;

• inflammatory skin diseases;

• thrombophlebitis;

• acne,

• furunculosis (as part of complex therapy).

Outwardly. In the form of compresses, tampons, mainly in aqueous solutions of 30-50% concentration. In the treatment of erysipelas and trophic ulcers, Dimexide is used in 30-50% aqueous solutions, 50-100 ml 2-3 times a day. For eczema, diffuse streptoderma, compresses with 40-90% Dimexide solution are recommended. For pustular skin diseases, a 40% solution of Dimexidum is used.
For local anesthesia for pain syndromes, a 25-50% solution is prescribed in the form of compresses, 100-150 ml 2-3 times a day. In the treatment of deep burns, dressings with a 20-30% solution of Dimexidum are used.

Concentrate for preparation of solution for external use 100 ml

dimethyl sulfoxide

• Impaired liver and / or kidney function,

• angina pectoris,

• myocardial infarction,

• severe atherosclerosis,

• glaucoma,

• cataract,

• coma,

• pregnancy,

• lactation.

pharmachologic effect

Anti-inflammatory agent for external use. The mechanism of action is associated with the inactivation of hydroxyl radicals and the improvement of metabolic processes in the focus of inflammation, a decrease in the rate of conduction of excitatory impulses in peripheral neurons. It has a local anesthetic, local anti-inflammatory, analgesic and antimicrobial effect; has some fibrinolytic activity. Penetrates through the skin and other biological membranes, increases their permeability to medicinal substances.

Side effect

Possibly: allergic reactions, itchy dermatitis, contact dermatitis, erythema, dry skin, slight burning sensation.

Rarely: bronchospasm.

Application during pregnancy and lactation

Dimethyl sulfoxide is contraindicated during pregnancy and lactation (breastfeeding).

Application for violations of liver function

Contraindicated in liver dysfunction.

Application for impaired renal function

Contraindicated in renal impairment.

special instructions

Dimethyl sulfoxide is used with caution in conjunction with other drugs, since it can enhance their effect.

Before using dimethyl sulfoxide, it is recommended to carry out a drug tolerance test.

Drug interactions

It is possible to use dimethyl sulfoxide in combination with heparin, antibiotics and NSAIDs in dosage forms for external use.

Increases absorption and enhances the effect of ethanol, insulin.

Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics, chloramphenicol, rifampicin, griseofulvin.

Sensitizes the body to general anesthetics.