Diclofenac gel d / nar. approx. 5% 50g

Package quantity 50 g Dosage form gel for external use Manufacturer Synthesis ACOMP, Russia Composition Active ingredient: sodium diclofenac 50 mg Pharmacological action Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. Inhibits the COX enzyme in the cascade of arachidonic acid metabolism and disrupts the biosynthesis of prostaglandins. When applied externally, it has anti-inflammatory and analgesic effects. Reduces and relieves pain at the site of application of the ointment (including joint pain at rest and during movement), reduces morning stiffness and swelling of the joints. Promotes increased range of motion. Indications for inflammatory and degenerative diseases of the joints (osteochondrosis, osteoarthritis, periarthropathy) rheumatism of soft tissues traumatic bruises sprains of ligaments, muscles and tendons inflammatory edema of soft tissues arthralgia and myalgia caused by heavy physical exertion. Contraindications pathological changes in the blood picture of unclear genesis peptic ulcer of the stomach and duodenum destructive-inflammatory bowel diseases in the acute phase pregnancy lactation period (you should stop breastfeeding) children and adolescents up to 12 years old (intramuscular injection, supp.) children under 6 years of age (tablets, ointment) hypersensitivity to acetylsalicylic acid or other NSAIDs (including the aspirin triad") hypersensitivity to diclofenac and other components of the drug inflammation of the rectum - proctitis (suppositories) Side effects At the site of application, skin rash, burning, redness are possible.With prolonged external use of the drug, it is possible to develop systemic side effects from the digestive system, central nervous system, respiratory system, as well as allergic reactions. Interaction With the simultaneous use of the drug Diclofenac with digoxin, phenytoin or lithium preparations, it is possible to increase the plasma concentrations of these drugs with diuretics and antihypertensive drugs - it is possible to reduce the effect of these drugs with potassium-sparing diuretics - hyperkalemia may develop with acetisalicylic acid - a decrease in the concentration of diclofenac in the blood plasma and an increased risk of side effects. Diclofenac may increase the toxic effect of cyclosporine on the kidneys. Diclofenc may cause hypo- or hyperglycemia,therefore, when used simultaneously with hypoglycemic agents, control of the concentration of glucose in the blood is required. When using methotrexate within 24 hours before or after taking Diclofenac, an increase in the concentration of methotrexate and an increase in its toxic effect is possible. With simultaneous use with anticoagulants, regular monitoring of blood coagulation indicators is necessary. How to take, course of administration and dosage In a dose of 2-4 g, apply a thin layer on the skin over the focus of inflammation and rub lightly, the frequency of use is 2-3 times a day. The maximum daily dose of the ointment should not exceed 8 g. The course of treatment is no more than 14 days. The need for a longer use of the drug is determined by the doctor. Special instructions Avoid getting Diclofenac gel on the damaged surface of the skin, open wounds, eyes and mucous membranes.The use of Diclofenac in the form of an ointment is possible only as prescribed by a doctor in the following cases: a history of gastric ulcer and duodenal ulcer impaired liver and kidney function severe violations of the hematopoietic system bronchial asthma, rhinitis, polyps of the nasal mucosa a history of allergic reactions. Use the drug with caution along with other NSAIDs. Use in pediatrics If it is necessary to use the drug in the form of an ointment in children under 6 years of age, medical supervision is required. Influence on the ability to drive a car and control mechanisms Due to the fact that when using the drug in high doses ofsevere violations of the hematopoietic system bronchial asthma, rhinitis, polyps of the nasal mucosa a history of allergic reactions. Use the drug with caution along with other NSAIDs. Use in pediatrics If it is necessary to use the drug in the form of an ointment in children under 6 years of age, medical supervision is required. Influence on the ability to drive a car and control mechanisms Due to the fact that when using the drug in high doses ofsevere violations of the hematopoietic system bronchial asthma, rhinitis, polyps of the nasal mucosa a history of allergic reactions. Use the drug with caution along with other NSAIDs. Use in pediatrics If it is necessary to use the drug in the form of an ointment in children under 6 years of age, medical supervision is required. Influence on the ability to drive a car and control mechanisms Due to the fact that when using the drug in high doses ofInfluence on the ability to drive a car and control mechanisms Due to the fact that when using the drug in high doses ofInfluence on the ability to drive a car and control mechanisms Due to the fact that when using the drug in high doses of

Name ENG

DICLOFENAC

Clinical and pharmacological group

NSAIDs for external use

ATX code

Diclofenac

Dosage

5% x 50g

Structure

Active ingredient: diclofenac sodium 50 mg

Indications

Inflammatory and degenerative diseases of the joints (osteochondrosis, osteoarthritis, periarthropathy)

- rheumatism of soft tissues

- traumatic bruises

- sprains of ligaments, muscles and tendons

- inflammatory edema of soft tissues

- arthralgia and myalgia caused by heavy physical exertion.

INN / Active ingredient

diclofenac diethylamine

Storage conditions and periods

At a temperature of 15-25 degrees (do not freeze).

Expiration date: 3 years

Contraindications

Hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs.

Complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses, angioedema or urticaria and intolerance to acetylsalicylic acid or other NSAIDs (including a history).

Pregnancy (III trimester), breastfeeding period, childhood (up to 12 years).

Violation of the integrity of the skin at the intended site of application.

Specifications

Category

Bruises, sprains

Scope of the drug

Musculoskeletal system

Release form

Gel

Manufacturer country

Russia

Package quantity, pcs

one

Minimum age from

6 years

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Synthesis

The amount of the dosage form in the primary package

50 g

Primary packaging type

Tuba

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

NSAIDs

Anatomical and therapeutic characteristics

M02AA15 Diclofenac

Dosage form

Gel for external use

The target audience

Children

Expiration date in days

1095

Dosage (volume) of the substance in the preparation

diclofenac sodium 50 mg

Package weight, g

fifty

Mode of application

:

At a dose of 2-4 g, apply a thin layer on the skin over the focus of inflammation and rub it lightly, the frequency of use is 2-3 times a day.

Drug action

:

Pain reliever

,

Anti-inflammatory

,

Analgesic

,

Antipyretic

Information on technical characteristics, delivery set, country of manufacture "