Diclofenac | Diklak gel 5%, 50 g
Special Price
$18.43
Regular Price
$26.00
In stock
SKU
BID475848
Latin name
Selmevit Intensiv
Selmevit Intensiv
Latin name
Selmevit Intensiv
release form
Gel for external use
Packing
tube 50 ml.
Pharmacological action
The active ingredient diclofenac is a non-steroidal anti-inflammatory drug (NSAID) with pronounced analgesic and anti-inflammatory properties.
Indiscriminately inhibiting type 1 and 2 cyclooxygenase (COX 1 and COX 2), disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation.
Diclofenac is used to relieve inflammation and eliminate pain, as well as reduce swelling, associated with the inflammatory process.
Pharmacokinetics
With the recommended method of application, no more than 6% of diclofenac is absorbed. When applied to the affected joint, the concentration in the synovial fluid is higher than in the blood plasma.
Selected patient groups
In patients with impaired renal function, diclofenac and its metabolites do not accumulate.
In patients with chronic hepatitis or subcompensated cirrhosis, the pharmacokinetics and metabolism of diclofenac are comparable to those in healthy patients.
Indications
• Diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of the peripheral joints and spine rheumatic soft tissue lesions.
• Muscle pains of rheumatic and non-rheumatic origin.
• Traumatic soft tissue injuries.
Contraindications
Hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs, “aspirin” asthma, pregnancy (III trimester), lactation, children (up to 6 years), impaired skin integrity.
Precautions: hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe impaired liver and kidney function, chronic heart failure, bronchial asthma, old age, pregnancy I and II trimester.
Use during pregnancy and lactation
The drug cannot be used in the III trimester of pregnancy. There is no experience with the use of the drug Diklak В® during lactation.
Use in the I and II trimesters is possible only after consultation with a doctor.
Composition
100 g of the preparation contains: active substance: diclofenac sodium? 5.0 g
excipients: isopropyl alcohol? 45.0 g purified water? 40.8 g macrogol-7-glycerol-cocoate - 6.0 g hypromellose - 3.0 g Bouquet aromatic oil WN 4507 - 0.2 g.
Dosage and Administration
Externally. For adults and children over 6 years of age, the drug is applied to the skin 2-3 times a day and rubbed lightly. The required amount of the drug depends on the size of the painful area. A single dose of the drug is up to 2 g (about 4 cm with the neck of the tube fully open). After applying the drug, hands should be washed. The duration of treatment depends on the indications and the observed effect. After 2 weeks of using the drug, consult your doctor.
Side effects
According to the World Health Organization (WHO), adverse reactions are classified according to their frequency of development as follows: very often ( 1/10), often ( 1/100, from the immune system very rarely: allergic reactions hypersensitivity (including urticaria, angioedema, bronchospasm).
from the respiratory system is very rare: bronchial asthma.
from the skin and subcutaneous tissue often: dermatitis (including contact dermatitis), erythema, eczema, itching, swelling the treated area of the skin, rash (papules, vesicles), peeling rarely: bullous dermatitis, pustular rashes are very rare: photosensitivity, generalized skin rash.
Drug Interaction
With the simultaneous use of the drug Diclac with digoxin, phenytoin or lithium drugs, it is possible to increase the plasma concentrations of these drugs with diuretics and antihypertensives - possibly reduce the action of these drugs with potassium resilience blood plasma and increased risk of side effects.
Diclofenac may increase the toxic effect of cyclosporine on the kidneys.
Diclofenc can cause hypo- or hyperglycemia, therefore, when administered with hypoglycemic agents, blood glucose monitoring is required.
When using methotrexate for 24 hours before or after taking Diclofenac, it is possible to increase the concentration of methotrexate and increase its toxic effect.
When co-administered with anticoagulants, regular monitoring of blood coagulation is required.
Overdose
Extremely low systemic absorption of the active component of the drug when used externally makes overdose almost impossible.
Storage conditions
Store in a dry, dark place at a temperature of no higher than 25 C.
Expiration
3 years.
Deystvuyuschee substances
Diclofenac
Sundlk pharmacy terms and conditions without prescription sdflfp32 aprf30 p46products
Over-the-counter
Sandoz, Switzerland
Selmevit Intensiv
release form
Gel for external use
Packing
tube 50 ml.
Pharmacological action
The active ingredient diclofenac is a non-steroidal anti-inflammatory drug (NSAID) with pronounced analgesic and anti-inflammatory properties.
Indiscriminately inhibiting type 1 and 2 cyclooxygenase (COX 1 and COX 2), disrupts the metabolism of arachidonic acid and the synthesis of prostaglandins, which are the main link in the development of inflammation.
Diclofenac is used to relieve inflammation and eliminate pain, as well as reduce swelling, associated with the inflammatory process.
Pharmacokinetics
With the recommended method of application, no more than 6% of diclofenac is absorbed. When applied to the affected joint, the concentration in the synovial fluid is higher than in the blood plasma.
Selected patient groups
In patients with impaired renal function, diclofenac and its metabolites do not accumulate.
In patients with chronic hepatitis or subcompensated cirrhosis, the pharmacokinetics and metabolism of diclofenac are comparable to those in healthy patients.
Indications
• Diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, osteoarthritis of the peripheral joints and spine rheumatic soft tissue lesions.
• Muscle pains of rheumatic and non-rheumatic origin.
• Traumatic soft tissue injuries.
Contraindications
Hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs, “aspirin” asthma, pregnancy (III trimester), lactation, children (up to 6 years), impaired skin integrity.
Precautions: hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract, severe impaired liver and kidney function, chronic heart failure, bronchial asthma, old age, pregnancy I and II trimester.
Use during pregnancy and lactation
The drug cannot be used in the III trimester of pregnancy. There is no experience with the use of the drug Diklak В® during lactation.
Use in the I and II trimesters is possible only after consultation with a doctor.
Composition
100 g of the preparation contains: active substance: diclofenac sodium? 5.0 g
excipients: isopropyl alcohol? 45.0 g purified water? 40.8 g macrogol-7-glycerol-cocoate - 6.0 g hypromellose - 3.0 g Bouquet aromatic oil WN 4507 - 0.2 g.
Dosage and Administration
Externally. For adults and children over 6 years of age, the drug is applied to the skin 2-3 times a day and rubbed lightly. The required amount of the drug depends on the size of the painful area. A single dose of the drug is up to 2 g (about 4 cm with the neck of the tube fully open). After applying the drug, hands should be washed. The duration of treatment depends on the indications and the observed effect. After 2 weeks of using the drug, consult your doctor.
Side effects
According to the World Health Organization (WHO), adverse reactions are classified according to their frequency of development as follows: very often ( 1/10), often ( 1/100, from the immune system very rarely: allergic reactions hypersensitivity (including urticaria, angioedema, bronchospasm).
from the respiratory system is very rare: bronchial asthma.
from the skin and subcutaneous tissue often: dermatitis (including contact dermatitis), erythema, eczema, itching, swelling the treated area of the skin, rash (papules, vesicles), peeling rarely: bullous dermatitis, pustular rashes are very rare: photosensitivity, generalized skin rash.
Drug Interaction
With the simultaneous use of the drug Diclac with digoxin, phenytoin or lithium drugs, it is possible to increase the plasma concentrations of these drugs with diuretics and antihypertensives - possibly reduce the action of these drugs with potassium resilience blood plasma and increased risk of side effects.
Diclofenac may increase the toxic effect of cyclosporine on the kidneys.
Diclofenc can cause hypo- or hyperglycemia, therefore, when administered with hypoglycemic agents, blood glucose monitoring is required.
When using methotrexate for 24 hours before or after taking Diclofenac, it is possible to increase the concentration of methotrexate and increase its toxic effect.
When co-administered with anticoagulants, regular monitoring of blood coagulation is required.
Overdose
Extremely low systemic absorption of the active component of the drug when used externally makes overdose almost impossible.
Storage conditions
Store in a dry, dark place at a temperature of no higher than 25 C.
Expiration
3 years.
Deystvuyuschee substances
Diclofenac
Sundlk pharmacy terms and conditions without prescription sdflfp32 aprf30 p46products
Over-the-counter
Sandoz, Switzerland
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