Diclofenac | Diclofenac rectal suppository 50 mg, 10 pcs.
Special Price
$14.55
Regular Price
$22.00
In stock
SKU
BID521351
Release form
Rectal suppositories.
Rectal suppositories.
Release form
Rectal suppositories.
Packing
10 pcs.
Pharmacological action
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. It inhibits the COX enzyme in the cascade of arachidonic acid metabolism and disrupts the biosynthesis of prostaglandins.
When used externally, it has anti-inflammatory and analgesic effects. Reduces and relieves pain at the site of ointment application (including joint pain at rest and during movement), reduces morning stiffness and swelling of joints. Helps increase range of motion.
Composition
Active ingredient: diclofenac 50 mg
Excipients: 1,2-propylene glycol, aerosil, witepsol.
Dosage and administration
Rectally. Adults: 100 mg 1 time per day, 50 mg 2 times a day or 25 mg 3-4 times a day.
The maximum daily dose is 150 mg.
Children over 12 years of age: 50 mg 1-2 times a day or 25 mg 2-3 times a day.
Side effects of the digestive system: nausea, vomiting, epigastric pain, anorexia, flatulence, constipation, gastritis, even erosive with bleeding, increased transaminase activity, drug hepatitis, pancreatitis.
Urinary system: interstitial nephritis.
From the side of the central nervous system: headache, dizziness, disorientation, agitation, insomnia, irritability, fatigue, aseptic meningitis.
From the respiratory system: bronchospasm.
From the hemopoietic system: anemia, thrombocytopenia, leukopenia, agranulocytosis.
Dermatological reactions: exanthema, erythema, eczema, hyperemia, erythroderma, photosensitivity.
Allergic reactions: erythema multiforme, Lyell syndrome, Stevens-Johnson syndrome, anaphylactic reactions, including shock.
Local reactions: burning, formation of infiltrate, adipose tissue necrosis are possible at the injection site.
Other: fluid retention, edema, increased blood pressure.
Drug interaction
With the simultaneous use of the drug Diclofenac with digoxin, phenytoin or lithium drugs, it is possible to increase plasma concentrations of these drugs with diuretics and antihypertensive agents - it is possible to decrease the effect of these drugs with potassium-sparing diuretics - hyperkalemia with acetysalicylic acid may develop in blood plasma and an increased risk of side effects.
Diclofenac may enhance the toxic effects of cyclosporine on the kidneys.
Diclofenk may cause hypo- or hyperglycemia, therefore, with simultaneous use with hypoglycemic agents, control of the concentration of glucose in the blood is required.
When methotrexate is used within 24 hours before or after taking Diclofenac, an increase in the concentration of methotrexate and an increase in its toxic effect are possible.
With simultaneous use with anticoagulants, regular monitoring of blood coagulation is necessary.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 РC. Keep out of the reach of children.
active substance
Diclofenac
Dosage form
suppositories rectal
Russia, Russia, Russia biosynthesis
Rectal suppositories.
Packing
10 pcs.
Pharmacological action
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. It inhibits the COX enzyme in the cascade of arachidonic acid metabolism and disrupts the biosynthesis of prostaglandins.
When used externally, it has anti-inflammatory and analgesic effects. Reduces and relieves pain at the site of ointment application (including joint pain at rest and during movement), reduces morning stiffness and swelling of joints. Helps increase range of motion.
Composition
Active ingredient: diclofenac 50 mg
Excipients: 1,2-propylene glycol, aerosil, witepsol.
Dosage and administration
Rectally. Adults: 100 mg 1 time per day, 50 mg 2 times a day or 25 mg 3-4 times a day.
The maximum daily dose is 150 mg.
Children over 12 years of age: 50 mg 1-2 times a day or 25 mg 2-3 times a day.
Side effects of the digestive system: nausea, vomiting, epigastric pain, anorexia, flatulence, constipation, gastritis, even erosive with bleeding, increased transaminase activity, drug hepatitis, pancreatitis.
Urinary system: interstitial nephritis.
From the side of the central nervous system: headache, dizziness, disorientation, agitation, insomnia, irritability, fatigue, aseptic meningitis.
From the respiratory system: bronchospasm.
From the hemopoietic system: anemia, thrombocytopenia, leukopenia, agranulocytosis.
Dermatological reactions: exanthema, erythema, eczema, hyperemia, erythroderma, photosensitivity.
Allergic reactions: erythema multiforme, Lyell syndrome, Stevens-Johnson syndrome, anaphylactic reactions, including shock.
Local reactions: burning, formation of infiltrate, adipose tissue necrosis are possible at the injection site.
Other: fluid retention, edema, increased blood pressure.
Drug interaction
With the simultaneous use of the drug Diclofenac with digoxin, phenytoin or lithium drugs, it is possible to increase plasma concentrations of these drugs with diuretics and antihypertensive agents - it is possible to decrease the effect of these drugs with potassium-sparing diuretics - hyperkalemia with acetysalicylic acid may develop in blood plasma and an increased risk of side effects.
Diclofenac may enhance the toxic effects of cyclosporine on the kidneys.
Diclofenk may cause hypo- or hyperglycemia, therefore, with simultaneous use with hypoglycemic agents, control of the concentration of glucose in the blood is required.
When methotrexate is used within 24 hours before or after taking Diclofenac, an increase in the concentration of methotrexate and an increase in its toxic effect are possible.
With simultaneous use with anticoagulants, regular monitoring of blood coagulation is necessary.
Storage conditions
Store in a dry, dark place at a temperature not exceeding 25 РC. Keep out of the reach of children.
active substance
Diclofenac
Dosage form
suppositories rectal
Russia, Russia, Russia biosynthesis
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