Diclofenac | Diclofenac gel 5%, 5%, 5% 30 g

Release form

gel

Packaging

Tuba '30

Pharmacological Action

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It has anti-inflammatory, analgesic and antipyretic effects. It inhibits the COX enzyme in the cascade of arachidonic acid metabolism and disrupts the biosynthesis of prostaglandins.

When used externally, it has anti-inflammatory and analgesic effects. Reduces and relieves pain at the site of ointment application (including joint pain at rest and during movement), reduces morning stiffness and swelling of joints. Helps increase range of motion.

Indications

- inflammatory and degenerative joint diseases (osteochondrosis, osteoarthrosis, periarthropathy)

- soft tissue rheumatism

- traumatic bruises

- sprains, muscles and tendons

- inflammatory swelling of soft tissues

- arthralgia and myalgia caused by severe physical exertion.

Contraindications

- pathological changes in the blood picture of unknown origin

- peptic ulcer of the stomach and duodenum

- destructive and inflammatory bowel disease in the acute phase

- pregnancy

- lactation 12 years (intramuscular administration, supp.)

- children under 6 years of age (tablets, ointment)

- hypersensitivity to acetylsalicylic acid or other NSAIDs (including aspirin triad)

- hypersensitivity to diclofenac and other components of the drug

Special instructions

Avoid contact with Diclofenac Gel on damaged skin, open wounds, eyes and mucous membranes.

Composition of

1 g of gel contains 50 mg sodium diclofenac

Dosage and administration

Gel in a dose of 2-4 g is applied in a thin layer on the skin over the site of inflammation and gently rubbed, the frequency of use is 2-3 times / day.

The maximum daily dose of ointment should not exceed 8 g.

The course of treatment is no more than 14 days. The need for a longer use of the drug is determined by the doctor.

Side effects

Skin rashes, burning, redness are possible at the place where the ointment is applied. With prolonged external use of the drug, it is possible to develop systemic side effects from the digestive system, central nervous system, respiratory system, as well as allergic reactions.

Drug interaction

With the simultaneous use of the drug Diclofenac with digoxin, phenytoin or lithium drugs, it is possible to increase plasma concentrations of these drugs with diuretics and antihypertensive agents - it is possible to decrease the effect of these drugs with potassium-sparing diuretics - hyperkalemia with acetysalicylic acid may develop in blood plasma and an increased risk of side effects.

Diclofenac may enhance the toxic effects of cyclosporine on the kidneys.

Diclofenk may cause hypo- or hyperglycemia, therefore, with simultaneous use with hypoglycemic agents, control of the concentration of glucose in the blood is required.

When methotrexate is used within 24 hours before or after taking Diclofenac, an increase in the concentration of methotrexate and an increase in its toxic effect are possible.

With simultaneous use with anticoagulants, regular monitoring of blood coagulation is necessary.

Storage conditions for

in a dry place at a temperature of 8 to 15 РC. Freezing is not allowed.

Expiration

See packaging.

Active ingredient

Diclofenac

Dispensing conditions at pharmacies

Over-the-counter

Form of Treatment

claim the gel dlya naruzhnogo primeneniya

Synthesis AKOMP, Russia