Dibazol tablets 20mg, No. 10

Arterial hypertension, hypertensive crisis.

Spasms of smooth muscles of internal organs (including stomach, intestines).

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Relief of hypertensive crisis - intravenous or intramuscularly 30-40 mg. Exacerbation of the course of arterial hypertension with a significant increase in blood pressure - intramuscularly, 20-30 mg 2-3 times / day, the course of treatment is 8-14 days.

Inside - 20-50 mg 2-3 times / day for 3-4 weeks.

In the treatment of nervous diseases - for adults at a dose of 5 mg 1 time / day or every other day for 5-10 days, after 3-4 weeks the course of treatment is repeated. In the future, courses are held with a break of 1-2 months.

For children, depending on age, the dose is 1-5 mg 1 time / day.

Bendazole - 20 mg

Hypersensitivity to bendazole; pregnancy, breastfeeding period; children under 18 years of age (for parenteral use).

Clinical and pharmacological group: Myotropic antispasmodic

Pharmaco-therapeutic group: Vasodilating agent

pharmachologic effect

Myotropic antispasmodic agent, a benzimidazole derivative. It has an antispasmodic effect on the smooth muscles of blood vessels and internal organs. Lowers blood pressure by reducing cardiac output and expansion of peripheral vessels. The hypotensive activity of bendazole is very moderate, and the effect is short-lived.

Causes a short expansion of cerebral vessels.

Facilitates synaptic transmission in the spinal cord.

Immunostimulating activity is associated with the regulation of the ratio of the concentrations of cGMP and cAMP in immune cells (increases the content of cGMP), which leads to the proliferation of mature sensitized T- and B-lymphocytes, their secretion of factors of mutual regulation, cooperative response and activation of the final effector function of cells.

Indications

Arterial hypertension, hypertensive crisis.

Spasms of smooth muscles of internal organs (including stomach, intestines).

Dosage regimen

The method of application and dosage regimen of a particular drug depends on its form of release and other factors. The optimal dosage regimen is determined by the doctor. It is necessary to strictly observe the compliance of the used dosage form of a particular drug with the indications for use and the dosage regimen.

Relief of hypertensive crisis - intravenous or intramuscularly 30-40 mg. Exacerbation of the course of arterial hypertension with a significant increase in blood pressure - intramuscularly, 20-30 mg 2-3 times / day, the course of treatment is 8-14 days.

Inside - 20-50 mg 2-3 times / day for 3-4 weeks.

In the treatment of nervous diseases - for adults at a dose of 5 mg 1 time / day or every other day for 5-10 days, after 3-4 weeks the course of treatment is repeated. In the future, courses are held with a break of 1-2 months.

For children, depending on age, the dose is 1-5 mg 1 time / day.

Side effect

Possibly: allergic reactions.

With prolonged use: deterioration of ECG indicators due to a decrease in cardiac output.

When used in high doses: feeling of heat, increased sweating, dizziness, nausea, headache.

Contraindications for use

Hypersensitivity to bendazole; pregnancy, breastfeeding period; children under 18 years of age (for parenteral use).

Application during pregnancy and lactation

Use during pregnancy and breastfeeding is contraindicated.

Application in children

Parenteral use is contraindicated in children and adolescents under the age of 18 years.

Use in elderly patients

Use with caution in elderly patients in order to avoid worsening of the course of concomitant diseases.

It is not recommended for long-term treatment of arterial hypertension, especially in elderly patients.

special instructions

Use with caution in elderly patients.

It is not recommended for long-term treatment of arterial hypertension, especially in elderly patients.

Drug interactions

With simultaneous use with antihypertensive drugs, diuretics, an increase in the antihypertensive effect is possible.

Concomitant use of bendazole prevents an increase in OPSS caused by beta-blockers.

With the simultaneous use of phentolamine enhances the hypotensive effect of bendazole.