Dexalgin gran. d / prigot. r-ra d / int. reception 25mg # 10
Category
Pain relievers
,
Migraine
Scope of the drug
General
Release form
Granules
Manufacturer country
Spain
Package quantity, pcs
ten
pharmachologic effect
NSAID, a derivative of phenylacetic acid.
It has a pronounced anti-inflammatory, analgesic and moderate antipyretic effect.
The mechanism of action is associated with inhibition of the activity of COX, the main enzyme of the metabolism of arachidonic acid, which is a precursor of prostaglandins, which play a major role in the pathogenesis of inflammation, pain and fever.
The analgesic effect is due to two mechanisms: peripheral (indirectly, through suppression of prostaglandin synthesis) and central (due to inhibition of prostaglandin synthesis in the central and peripheral nervous system).
Inhibits the synthesis of proteoglycan in cartilage.
In rheumatic diseases, it reduces joint pain at rest and during movement, as well as morning stiffness and swelling of the joints, and helps to increase the range of motion.
Reduces post-traumatic and postoperative pain, as well as inflammatory edema.
Suppresses platelet aggregation.
With prolonged use, it has a desensitizing effect.
When applied topically in ophthalmology, it reduces edema and pain in inflammatory processes of non-infectious etiology.
Indications
Inflammatory and degenerative diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic, juvenile chronic arthritis, ankylosing spondylitis
rheumatic lesions of soft tissues
gouty arthritis)
traumatic inflammation of the tendons, ligaments, muscles and joints (as a result of sprains, stress and bruises).
Contraindications
- complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses, and intolerance to acetylsalicylic acid or other NSAIDs (in history)
- violation of the integrity of the skin
- pregnancy (III trimester)
- lactation period
- children's age (up to 12 years old)
- hypersensitivity to diclofenac or other components of the drug, acetylsalicylic acid or other NSAIDs.
Carefully
Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract (in the exacerbation phase), severe liver and kidney dysfunction, chronic heart failure, bleeding disorders (including hemophilia, prolonged bleeding time, tendency to bleed)
bronchial asthma, advanced age, pregnancy I and II trimester.
Application during pregnancy and lactation
Use during pregnancy (III trimester) and lactation is contraindicated.
With care: pregnancy I and II trimester.
special instructions
The gel is applied only to intact skin areas.
After application, do not apply an occlusive dressing.
When applied to large skin surfaces for a long time, the risk of developing systemic side effects increases.
Avoid getting the drug in the eyes, mucous membranes or open brines.
Use as an external agent only.
Structure
100 g of gel contains:
Active substance
Diclofenac diethylamine 1.16 g.
Which corresponds to diclofenac sodium 1.00 g.
Excipients
Isopropyl alcohol, carbopol 940, polysorbate 80, gasoline alcohol, sodium metabisulfite, sorbitol 70% non-crystallizing, triethanolamine, purified water.
Method of administration and dosage
Outwardly.
For adults and children over 12 years old, the drug is applied in a thin layer over the focus of inflammation 3-4 times / day and rubbed lightly.
The required amount of the drug depends on the size of the painful area.
Single dose of the drug: 2-4 g (which is comparable in volume to the size of a large cherry).
After applying the drug, you must wash your hands.
The duration of treatment depends on the indications and the therapeutic effect.
After 2 weeks of using the drug, you should consult your doctor.
Side effects
From the digestive system: nausea, vomiting, anorexia, pain and discomfort in the epigastric region, flatulence, constipation, diarrhea
in some cases - erosive and ulcerative lesions, bleeding and perforation of the gastrointestinal tract
rarely - liver dysfunction.
With rectal administration, in isolated cases, there was inflammation of the colon with bleeding, exacerbation of ulcerative colitis.
From the side of the central nervous system and peripheral nervous system: dizziness, headache, agitation, insomnia, irritability, fatigue
rarely - paresthesias, visual impairments (blurred, diplopia), tinnitus, sleep disorders, convulsions, irritability, tremors, mental disorders, depression.
From the hematopoietic system: rarely - anemia, leukopenia, thrombocytopenia, agranulocytosis.
From the urinary system: rarely - impaired renal function
edema is possible in predisposed patients.
Dermatological reactions: rarely - hair loss.
Allergic reactions: skin rash, itching
when applied in the form of eye drops - itching, redness, photosensitivity.
Local reactions: at the place of intramuscular injection, burning is possible, in some cases - the formation of infiltration, abscess, necrosis of adipose tissue
with rectal administration, local irritation, the appearance of mucous secretions mixed with blood, painful defecation are possible
when applied externally in rare cases - itching, redness, rash, burning
when applied topically in ophthalmology, a transient burning sensation and / or temporary blurred vision may occur immediately after instillation.
With prolonged external use and / or application to extensive body surfaces, systemic side effects are possible due to the resorptive action of diclofenac.
Drug interactions
The drug can enhance the effect of drugs that cause photosensitization.
No clinically significant interaction with other drugs has been described.
Storage conditions
Keep out of the reach of children, at a temperature of 15 ° to 25 ° C.
Shelf life
3 years
Active substance
Diclofenac
Name ENG
DICLOFENAC
Clinical and pharmacological group
NSAIDs for external use
ATX code
Diclofenac
Dosage
1% x 100g
Structure
100 g of gel contains: Active ingredient. Diclofenac diethylamine 1.16 g. Which corresponds to diclofenac sodium 1.00 g. Excipients. Isopropyl alcohol, Carbopol 940, Polysorbate 80, gasoline alcohol, sodium metabisulfite, sorbitol 70% non-crystallizing, triethanolamine, purified water.
Indications
Inflammatory and degenerative diseases of the musculoskeletal system: rheumatoid arthritis, psoriatic, juvenile chronic arthritis, ankylosing spondylitis
rheumatic lesions of soft tissues
gouty arthritis)
traumatic inflammation of the tendons, ligaments, muscles and joints (as a result of sprains, stress and bruises).
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 4 years
after opening - 1 year
Contraindications
complete or incomplete combination of bronchial asthma, recurrent polyposis of the nose and paranasal sinuses, and intolerance to acetylsalicylic acid or other NSAIDs (in history)
violation of the integrity of the skin
pregnancy (III trimester)
lactation period
children's age (up to 12 years old)
hypersensitivity to diclofenac or other components of the drug acetylsalicylic acid or other NSAIDs., With caution, Hepatic porphyria (exacerbation), erosive and ulcerative lesions of the gastrointestinal tract (in the exacerbation phase), severe liver and kidney dysfunction, chronic heart failure, blood clotting disorder ( including hemophilia, lengthening of bleeding time, tendency to bleeding)
bronchial asthma, advanced age, pregnancy I and II trimester. <
INN / Active ingredient
Diclofenac
Specifications
Category
Anesthesia and muscle relaxants
,
Bruises, sprains
Scope of the drug
Musculoskeletal system
Release form
Gel
Manufacturer country
Germany
Package quantity, pcs
one
Scope of application
Orthopedics
Minimum age from
12 years
Way of introduction
Locally
,
Outwardly
Vacation conditions
Without recipe
Brand name
Teva
The amount of the dosage form in the primary package
100 g
Primary packaging type
Tuba
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
NSAIDs
Anatomical and therapeutic characteristics
M02AA15 Diclofenac
Dosage form
Gel for external use
Packaging
Cardboard box
The target audience
Children
Expiration date in days
1095
Dosage (volume) of the substance in the preparation
diclofenac sodium 10 mg
Drug action
Anti-inflammatory
,
Analgesic
,
Antipyretic
Package weight, g
135
Mode of application
: https://translate.google.com/translate?hl=&sl=ru&tl=en&u=https://zz.buy-pharm.com/xzzalgp.html;Description
Release form
Granules for preparation of oral solution
pharmachologic effect
NSAIDs.
It has anti-inflammatory, analgesic and antipyretic effects.
The mechanism of action is based on inhibition of prostaglandin synthesis due to suppression of COX.
The analgesic effect occurs 30 minutes after ingestion, the duration of the action is 4-6 hours.
Pharmacokinetics
After taking the drug inside, Cmax of dexketoprofen in humans is reached on average after 30 minutes (15-60 minutes).
Plasma protein binding - 99%.
Average Vd - less than 0.25 l / kg.
T1 / 2 is 1.65 hours. It is metabolized.
It is excreted mainly by the kidneys in the form of metabolites.
Indications
Pain syndrome of mild and moderate intensity in the following diseases and conditions: acute and chronic inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis)
dysmenorrhea
toothache.
Contraindications
Peptic ulcer and duodenal ulcer, gastrointestinal bleeding, active bleeding of various origins, increased bleeding, anticoagulant therapy, Crohn's disease, ulcerative colitis, bronchial asthma (including a history), severe heart failure, renal failure, liver insufficiency, pregnancy, lactation, hypersensitivity to dexketoprofen or other NSAIDs.
special instructions
Care should be taken when prescribing the drug to elderly patients, patients with allergic reactions, with systemic diseases of the connective tissue and patients with impaired blood formation.
Patients should be informed that in case of side effects, as well as in the absence of a clinical effect within 3-5 days of treatment, it is necessary to inform the attending physician about it.
Special care is required with the simultaneous use of dexketoprofen with phenytoin, sulfonamides and drugs that reduce blood clotting.
Influence on the ability to drive vehicles and use mechanisms
Since dexketoprofen can cause a decrease in the ability to concentrate, it should be used with caution in patients engaged in potentially hazardous activities that require increased attention and speed of psychomotor reactions.
Structure
1 pack.
dexketoprofen trometamol 36.9 mg, which corresponds to the content of dexketoprofen 25 mg.
Excipients: ammonium glycyrrhizinate - 2 mg, dihydrochalcone neohesperidin - 1.5 mg, quinoline yellow dye (E104) - 1.2 mg, lemon flavor - 40 mg, sucrose with colloidal silicon dioxide (500: 1) - 2418 mg.
Method of administration and dosage
Is taken internally.
The average recommended single dose is 12.5 mg - 1-6 times / day every 4-6 hours as needed or 25 mg 1-3 times / day every 8 hours.
The maximum daily dose is 75 mg.
The duration of use is no more than 3-5 days.
For patients with impaired liver or kidney function, the elderly, the initial dose is no more than 50 mg / day.
Side effects
From the digestive system: heartburn, abdominal pain
rarely - erosive and ulcerative lesions of the gastrointestinal tract.
From the nervous system: headaches, dizziness, nervousness, sleep disturbance, paresthesia.
From the side of the cardiovascular system: palpitations, increased blood pressure.
Allergic reactions: skin rash, bronchospasm.
Others: chills, swelling of the extremities, photosensitivity
rarely - a change in the picture of peripheral blood, renal dysfunction.
Drug interactions
With the simultaneous use of dexketoprofen with other NSAIDs, the risk of side effects may increase.
With simultaneous use with lithium preparations, an increase in the concentration of the latter in the blood plasma is possible.
Use dexketoprofen with caution less than 24 hours before the start of use or after the end of therapy with methotrexate, since the concentration of the latter in the blood plasma (and, therefore, toxicity) may increase.
Some cases of bleeding with the simultaneous use of NSAIDs and anticoagulants are described.
Active substance
Dexketoprofen
Storage conditions
Store at a temperature of 15-25 С out of the reach of children.
Name ENG
DEXALGIN
Clinical and pharmacological group
NSAIDs
ATX code
Dexketoprofen
Dosage
25mg x 2.5g
Structure
1 pack of dexketoprofen trometamol 36.9 mg, which corresponds to the content of dexketoprofen 25 mg Excipients: ammonium glycyrrhizinate - 2 mg, neohesperidin dihydrochalcone - 1.5 mg, quinoline yellow dye (E104) - 1.2 mg, lemon flavoring - 40 mg, sucrose with silicon colloidal (500: 1) - 2418 mg.
Indications
Pain syndrome of mild and moderate intensity in the following diseases and conditions: acute and chronic inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, spondyloarthritis, arthrosis, osteochondrosis)
dysmenorrhea
toothache.
Contraindications
Hypersensitivity to dexketoprofen or other NSAIDs
peptic ulcer of the stomach and duodenum
gastrointestinal bleeding
active bleeding of various origins
increased bleeding
anticoagulant therapy
Crohn's disease
nonspecific ulcerative colitis
bronchial asthma (including history)
severe heart failure
severe renal failure
severe liver failure
pregnancy and lactation.
INN / Active ingredient
Dexketoprofen
Storage conditions and periods
At a temperature not higher than 25 degrees.
Expiration date: 3 years
Specifications
Category
Pain relievers
,
Migraine
Scope of the drug
General
Release form
Granules
Manufacturer country
Spain
Package quantity, pcs
ten
Scope of application
Orthopedics
,
Dentistry
Way of introduction
Through the mouth
Vacation conditions
Without recipe
Brand name
Berlin-Chemie
The amount of the dosage form in the primary package
2.5 g
Primary packaging type
Sachet (sachet)
Type of consumer packaging
Pack of cardboard
Pharmaco-therapeutic group
NSAIDs
Anatomical and therapeutic characteristics
M01AE17 Dexketoprofen
Dosage form
Granules for preparation of oral solution
The target audience
Adult
Dosage (volume) of the substance in the preparation
dexketoprofen trometamol 36.9 mg
Expiration date in days
1095
Package weight, g
55
Mode of application
:
Is taken internally.
The average recommended single dose is 12.5 mg - 1-6 times / day every 4-6 hours as needed or 25 mg 1-3 times / day every 8 hours. < br> The maximum daily dose is 75 mg.
Duration of use - no more than 3-5 days. < br> For patients with impaired liver or kidney function, elderly people, the initial dose is no more than 50 mg / day. < br>
Information on technical characteristics, delivery set, country of manufacture "