Desloratadine tab. p / o captivity. 5mg # 10

Package quantity 10 Tablet dosage form Manufacturer Vertex, Russia Composition Film-coated tablets of blue color, round, biconvex in cross section, the core is white or almost white. 1 tab .: desloratadine 5 mg Excipients: calcium hydrogen phosphate dihydrate - 53 mg, microcrystalline cellulose - 27.5 mg, corn starch - 11 mg, talc - 2.5 mg, magnesium stearate - 1 mg. The composition of the film shell: dry mixture for film coating (polyvinyl alcohol - 40%, titanium dioxide - 22.1%, macragol 3350 (polyethylene glycol 3350) - 20.2%, talc - 14.8%, aluminum varnish based on indigo carmine dye - 2.8%, iron oxide yellow (iron oxide) - 0.1%) - 3 mg. Pharmacological action Pharmgroup: antiallergic agent - H1-histamine receptor blocker. Pharmaceutical action:H1-histamine receptor blocker (long-acting). It is the primary active metabolite of loratadine. Suppresses the release of histamine and leukotriene C4 from mast cells. Prevents the development and facilitates the course of allergic reactions. It has antiallergic, antipruritic and antiexudative effect. Reduces capillary permeability, prevents the development of tissue edema, relieves spasm of smooth muscles. It practically does not have a sedative effect and, when taken in a dose of 7.5 mg, does not affect the speed of psychomotor reactions. In comparative studies of desloratadine and loratadine, there were no qualitative or quantitative differences in the toxicity of 2 drugs in comparable doses (taking into account the concentration of desloratadine). Indications Seasonal and perennial allergic rhinitis, chronic idiopathic urticaria.Contraindications Hypersensitivity, pregnancy, lactation, children (up to 1 year), children (up to 12 years) for tablet forms. For syrup (additionally, due to the presence of sucrose and sorbitol in the composition): hereditary fructose intolerance, impaired glucose / galactose absorption or sucrose / isomaltose insufficiency. Carefully. Severe renal failure. Side effects Rarely: dizziness, drowsiness, tachycardia, palpitations, abdominal pain, dyspepsia (including nausea, vomiting, diarrhea), hyperbilirubinemia, increased activity of liver" enzymes, allergic reactions (skin rash, itching, urticaria, angioedema , anaphylactic shock). In children under 2 years of age (the frequency is slightly higher than when taking placebo): diarrhea, hyperthermia, insomnia.In 2-11 years, the incidence of side effects is comparable to placebo. In adults and children over 12 years of age (the frequency is slightly higher than when taking placebo): increased fatigue, dryness of the oral mucosa, headache drowsiness (frequency of occurrence is comparable to placebo). Interaction Interactions with other drugs have not been identified in studies with azithromycin, ketoconazole. erythromycin, fluoxetine and cimetidine. Food intake does not affect the effectiveness of the drug. Desloratadine does not potentiate the effects of alcohol on the central nervous system. How to take, course of administration and dosage Inside. The tablet should be swallowed whole, without chewing, with a little water. It is advisable to take the drug at the same time of day, regardless of the time of admission, write.Adults and adolescents from 12 years old - 1 tablet (5 mg) 1 time per day. The duration of therapy depends on the duration of the symptoms. For seasonal (intermittent) allergic rhinitis (symptoms lasting less than 4 days per week or total duration of less than 4 weeks per year) and urticaria, the disease should be assessed. If symptoms disappear, the drug should be discontinued, if symptoms reappear, the drug should be resumed. For perennial (persistent) allergic rhinitis (symptoms lasting more than 4 days a week or a total duration of more than 4 weeks a year), treatment canFor seasonal (intermittent) allergic rhinitis (symptoms lasting less than 4 days per week or total duration of less than 4 weeks per year) and urticaria, the disease should be assessed. If symptoms disappear, the drug should be discontinued, if symptoms reappear, the drug should be resumed. For perennial (persistent) allergic rhinitis (symptoms lasting more than 4 days a week or a total duration of more than 4 weeks a year), treatment canFor seasonal (intermittent) allergic rhinitis (symptoms lasting less than 4 days per week or total duration of less than 4 weeks per year) and urticaria, the disease should be assessed. If symptoms disappear, the drug should be discontinued, if symptoms reappear, the drug should be resumed. For perennial (persistent) allergic rhinitis (symptoms lasting more than 4 days a week or a total duration of more than 4 weeks a year), treatment canFor perennial (persistent) allergic rhinitis (symptoms lasting more than 4 days a week or a total duration of more than 4 weeks a year), treatment canFor perennial (persistent) allergic rhinitis (symptoms lasting more than 4 days a week or a total duration of more than 4 weeks a year), treatment can

Name ENG

DESLORATADINE

Clinical and pharmacological group

Blocker of histamine H1 receptors.

Antiallergic drug

ATX code

Desloratadine

Dosage

5mg

Structure

Film-coated tablets of blue color, round, biconvex

in cross section, the core is white or almost white.

Indications

Seasonal and perennial allergic rhinitis, chronic idiopathic urticaria.

Contraindications

Hypersensitivity, pregnancy, lactation, children (up to 1 year), children (up to 12 years) for tablet forms.

For syrup (additionally, due to the presence of sucrose and sorbitol in the composition): hereditary fructose intolerance, impaired glucose / galactose absorption or sucrose / isomaltose insufficiency.

Carefully.

Severe renal failure.

INN / Active ingredient

desloratadine

Storage conditions and periods

In a dark place at a temperature not exceeding 25 degrees.

Expiration date: 4 years

Specifications

Category

Allergy

Scope of the drug

Leather

Release form

Tablet

Manufacturer country

Russia

Package quantity, pcs

ten

Minimum age from

12 years

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Brand name

Vertex

The amount of the dosage form in the primary package

10 pieces.

Primary packaging type

Blister

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

R06AX27 Desloratadine

Dosage form

Film-coated tablets

Dosage (volume) of the substance in the preparation

desloratadine 5 mg

Expiration date in days

1460

Package weight, g

ten

Mode of application

:

Inside. The tablet should be swallowed whole, without chewing, with a little water. It is advisable to take the drug at the same time of day, regardless of the time of admission, write. Adults and adolescents from 12 years old - 1 tablet (5 mg) 1 time per day. The duration of therapy depends on the duration of the symptoms. For seasonal (intermittent) allergic rhinitis (symptoms lasting less than 4 days per week or total duration of less than 4 weeks per year) and urticaria, the disease should be assessed. If symptoms disappear, the drug should be discontinued, if symptoms reappear, the drug should be resumed.For perennial (persistent) allergic rhinitis (symptoms lasting more than 4 days a week or a total duration of more than 4 weeks a year), treatment can be continued for the entire period of exposure to allergens. To determine the duration of drug therapy, you must consult with your doctor.

Pharmaco-therapeutic group

:

Antiallergic agent - H1-histamine receptor blocker

Information on technical characteristics, delivery set, country of manufacture "