Desal oral solution 0.5 mg / ml vial. 100ml

Special Price $18.62 Regular Price $26.00
In stock
SKU
OTC10207527
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Category

Allergy

Scope of the drug

Leather

Release form

Solution

Manufacturer country

Bulgaria

Package quantity, pcs

one

Description

Release form Oral solution Packaging 100 ml bottle. Pharmacological action Desal is a histamine H1 receptor blocker (long-acting). It is the primary active metabolite of loratadine. Inhibits the release of histamine and leukotriene C4 from mast cells. Prevents the development and facilitates the course of allergic reactions. It has antiallergic, antipruritic and antiexudative effect. Reduces capillary permeability, prevents the development of tissue edema, relieves spasm of smooth muscles. It practically does not have a sedative effect and, when taken in a dose of 7.5 mg, does not affect the speed of psychomotor reactions. In comparative studies of desloratadine and loratadine, there were no qualitative or quantitative differences in the toxicity of the two drugs in comparable doses (taking into account the concentration of desloratadine).Pharmacokinetics After oral administration, it begins to be determined in plasma after 30 minutes. Food has no effect on distribution. Bioavailability is dose proportional, ranging from 5 mg to 20 mg. Plasma protein binding is 83-87%. Does not penetrate the blood-brain barrier (BBB). It is extensively metabolized in the liver by hydroxylation to form 3-OH-desloratadine, combined with glucuronide, only a small part of the dose taken orally is excreted by the kidneys (less than 2%) and with feces (less than 7%). Compositional analogs Erius tablets 5 mg, 10 pcs. Bayer Pharma AG Germany 584 rub. Erius syrup 2.5 mg / 5 ml, 60 ml Bayer Pharma AG Germany 672 rub. Lordestin tablets, film-coated. 5 mg 30 pcs. Gedeon Richter Hungary 783 RUR Lordestin tablets, film-coated. 5 mg 10 pcs. Gedeon Richter Hungary 359 RUR Elisey 5 mg tablets 30 pcs.Farmak Ukraine 379 rub. Desloratadine tablets, film-coated 5 mg 10 pcs. Vertex Russia 263 rubles. Indications Symptomatic therapy of seasonal and perennial allergic rhinitis, chronic idiopathic urticaria. Contraindications Hypersensitivity, pregnancy, breastfeeding. For syrup (additionally, due to the presence of sucrose and sorbitol in the composition): hereditarily transmitted fructose intolerance, impaired glucose / galactose absorption or sucrose / isomaltose insufficiency. Composition active substance: desloratadine 0.5 mg Dosing and Administration Adults and adolescents aged 12 years and older are prescribed orally, regardless of food intake, at a dose of 5 mg per day. Children aged 1 to 5 years - 1.25 mg once a day, aged 6 to 11 years - 2.5 mg once a day. Side effects Mental disorders: hallucinations.From the side of the central nervous system: dizziness, drowsiness, insomnia, psychomotor hyperactivity. On the part of the cardiovascular system: tachycardia, palpitations. From the digestive system: abdominal pain, nausea, vomiting, dyspepsia, diarrhea. From the liver and biliary tract: increased activity of liver enzymes, increased concentration of bilirubin, hepatitis. From the musculoskeletal system: myalgia. Allergic reactions: anaphylaxis, angioedema, itching, rash, urticaria. Storage conditions Store in a dry, protected from light, out of reach of children at a temperature not exceeding 25 ° C. Shelf life 2 years Active ingredient DesloratadineFrom the digestive system: abdominal pain, nausea, vomiting, dyspepsia, diarrhea. From the liver and biliary tract: increased activity of liver enzymes, increased concentration of bilirubin, hepatitis. From the musculoskeletal system: myalgia. Allergic reactions: anaphylaxis, angioedema, itching, rash, urticaria. Storage conditions Store in a dry, protected from light, out of reach of children at a temperature not exceeding 25 ° C. Shelf life 2 years Active ingredient DesloratadineFrom the digestive system: abdominal pain, nausea, vomiting, dyspepsia, diarrhea. From the liver and biliary tract: increased activity of liver enzymes, increased concentration of bilirubin, hepatitis. From the musculoskeletal system: myalgia. Allergic reactions: anaphylaxis, angioedema, itching, rash, urticaria. Storage conditions Store in a dry, protected from light, out of reach of children at a temperature not exceeding 25 ° C. Shelf life 2 years Active ingredient Desloratadineprotected from light, out of the reach of children, at a temperature not exceeding 25 ° C. Shelf life 2 years Active ingredient Desloratadineprotected from light, out of the reach of children, at a temperature not exceeding 25 ° C. Shelf life 2 years Active ingredient Desloratadine

Name ENG

DESAL

Clinical and pharmacological group

Blocker of histamine H1 receptors.

Antiallergic drug

ATX code

Desloratadine

Dosage

0.5mg / ml x 100ml

Structure

Active substance: desloratadine

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

INN / Active ingredient

desloratadine

Specifications

Category

Allergy

Scope of the drug

Leather

Release form

Solution

Manufacturer country

Bulgaria

Package quantity, pcs

one

Scope of application

Allergology

Minimum age from

1 year

Way of introduction

Through the mouth

Vacation conditions

Without recipe

Volume, ml.

100 ml

Brand name

Actavis

Components

syringe dispenser

The amount of the dosage form in the primary package

100 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Anatomical and therapeutic characteristics

R06AX27 Desloratadine

Dosage form

Oral solution

Dosage (volume) of the substance in the preparation

desloratadine 0.5 mg

Expiration date in days

1095

Package weight, g

210

Mode of application

:

Adults and adolescents aged 12 years and older are prescribed orally, regardless of food intake, at a dose of 5 mg per day.

Children aged 1 to 5 years - 1.25 mg once a day, aged 6 to 11 years - 2.5 mg once a day.

Pharmaco-therapeutic group

:

Antiallergic agent - H1-histamine receptor blocker

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