Derinat spray 0.25%, 10ml

Monotherapy:

acute respiratory diseases (ARI); prevention and treatment of acute respiratory viral infections (ARVI); ophthalmology: inflammatory and degenerative processes; inflammatory diseases of the mucous membranes of the oral cavity;

Complex therapy:

chronic inflammatory diseases, fungal, bacterial and other mucosal infections in gynecology; acute and chronic diseases of the upper respiratory tract (rhinitis, sinusitis, sinusitis, frontal sinusitis); obliterating diseases of the lower extremities; trophic ulcers, long-term non-healing and infected wounds (including diabetes mellitus); gangrene; burns, frostbite; hemorrhoids; post-radiation necrosis of the skin and mucous membranes.

Derinat in the form of a solution for external and local use is prescribed depending on the localization of the pathological process. The drug is prescribed for children from the first day of life and for adults. For the prevention of ARVI, 2 drops are instilled into each nasal passage 2-4 times a day for 1-2 weeks. When symptoms of a respiratory disease appear, the drug is instilled 2-3 drops into each nasal passage every 1-1.5 hours during the first day, then - 2-3 drops in each nasal passage 3-4 Duration of the course of therapy - from 5 days to 1 month. For inflammatory diseases of the nasal cavity and paranasal sinuses, the drug is instilled 3-5 drops into each nasal passage 4-6 times a day; the duration of the course is 7-15 days. In case of inflammatory diseases of the oral cavity, rinse the mouth with a solution of the drug 4-6 times a day (1 bottle for 2-3 rinses).The duration of the course of therapy is 5-10 days. For chronic inflammatory diseases, fungal, bacterial and other infections in gynecological practice - intravaginal administration of tampons with the drug or irrigation of the vagina and cervix, 5 ml per procedure 1-2 times a day for 10-14 days. For hemorrhoids, the drug is administered rectally using microclysters of 15-40 ml. The duration of the course of treatment is 4-10 days. In ophthalmic practice, for severe inflammatory and dystrophic processes, Derinat is instilled into the eyes 1-2 drops 2-3 times a day for 14-45 days. In case of obliterating diseases of the lower extremities, in order to achieve a systemic effect, the drug is instilled in 1-2 drops into each nasal passage 6 times a day, the duration of the course is up to 6 months. With post-radiation necrosis of the skin and mucous membranes,for long-term non-healing wounds, burns, frostbite, trophic ulcers of various etiologies, gangrene on the affected areas, it is recommended to apply application dressings (gauze in 2 layers) with the application of the drug 3-4 times a day or treat the affected surface with a drug from a nebulizer 10-40 ml 4 -5 times a day. The course of treatment is 1-3 months.

1 ml of solution contains

sodium deoxyribonucleate - 2.5 mg,

sodium chloride - 1.0 mg

Hypersensitivity to the components of the drug.

pharmachologic effect

The drug activates cellular and humoral immunity. Optimizes specific responses against fungal, viral and bacterial infections. The drug stimulates reparative and regenerative processes, normalizes the state of tissues and organs in case of dystrophies of vascular origin. Derinat promotes the healing of trophic ulcers of various etiologies. Derinat promotes rapid healing of deep burns, significantly accelerating the dynamics of epithelialization. With the restoration of ulcerative formations on the mucous membrane under the influence of Derinat, scarless restoration occurs. The drug has no teratogenic and carcinogenic effects.

Pharmacokinetics:

Derinat, when applied topically, is rapidly absorbed and distributed in organs and tissues with the participation of the endolymphatic transport pathway. In the phase of intensive intake of the drug into the blood, a redistribution occurs between plasma and blood cells, in parallel with metabolism and excretion. Derinat is metabolized in the body. It is excreted from the body (in the form of metabolites) partly with feces, and, to a greater extent, with urine according to a biexponential relationship.

Side effects

With external and local application of the drug, side effects were not identified.