Depantol suppositories 100 + 16mg, No. 10

Treatment of acute and chronic vaginitis; bacterial vaginosis; endo- / exocervicitis. Treatment of true erosions of the cervix of a specific etiology (as part of complex therapy).

Prevention of infectious and inflammatory complications in obstetrics and gynecology: before surgical treatment of gynecological diseases, delivery, medical termination of pregnancy, intrauterine examinations (including hysteroscopy, hysterosalpingography), before installing an intrauterine contraceptive.

The drug is used to improve the regeneration of the vaginal mucosa and cervix after destructive treatment methods (diathermocoagulation, cryodestruction, laser destruction), in the postoperative, postpartum periods.

Applied intravaginally. Before use, the suppository is released from the contour packaging.

Enter 1 suppository 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days.

If after treatment there is no improvement, or symptoms worsen, or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the route of administration and the doses indicated in the instructions for use.

One suppository contains:

active ingredients: dexpanthenol - 100 mg, chlorhexidine bigluconate solution 20% - 85.2 mg (in terms of chlorhexidine bigluconate - 16 mg);

excipients: a mixture of macrogols (macrogol 400 - 2%, macrogol 1500 - 98%).

Hypersensitivity to the components of the drug.

Trade name: Depantol

International non-proprietary name:

Dexpanthenol + Chlorhexidine

Dosage form:

vaginal suppositories

Composition:

One suppository contains:

active ingredients: dexpanthenol - 100 mg, chlorhexidine bigluconate solution 20% - 85.2 mg (in terms of chlorhexidine bigluconate - 16 mg);

excipients: a mixture of macrogols (macrogol 400 - 2%, macrogol 1500 - 98%).

Description:

Torpedo-shaped suppositories, white or white with a grayish or yellowish tint. Marbling and the presence of an air rod and a funnel-shaped depression on the cut are allowed.

Pharmacotherapeutic group:

Tissue repair stimulant

Pharmacological properties:

DepantolЃ is a combined topical preparation that has a regenerating, antiseptic, metabolic effect. Chlorhexidine, which is a part of the drug, is active against gram-positive and gram-negative bacteria: Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis, Escherichia coli, Stpp. Spp., yeast, dermatophytes, protozoa (Trichomonas vaginalis). Some strains of Pseudomonas spp., Proteus spp. Are weakly sensitive to the drug, as well as acid-resistant forms of bacteria, bacterial spores. Dexpanthenol, which is part of the drug, stimulates the regeneration of mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers.

DepantolЃ does not interfere with the functional activity of lactobacilli. Remains active (although somewhat reduced) in the presence of blood, pus.

Indications for use:

Treatment of acute and chronic vaginitis; bacterial vaginosis; endo- / exocervicitis. Treatment of true erosions of the cervix of a specific etiology (as part of complex therapy).

Prevention of infectious and inflammatory complications in obstetrics and gynecology: before surgical treatment of gynecological diseases, delivery, medical termination of pregnancy, intrauterine examinations (including hysteroscopy, hysterosalpingography), before installing an intrauterine contraceptive.

The drug is used to improve the regeneration of the vaginal mucosa and cervix after destructive treatment methods (diathermocoagulation, cryodestruction, laser destruction), in the postoperative, postpartum periods.

Contraindications:

Hypersensitivity to the components of the drug.

Application during pregnancy and during breastfeeding:

It can be used during pregnancy and during breastfeeding.

Method of administration and dosage:

Applied intravaginally. Before use, the suppository is released from the contour packaging.

Enter 1 suppository 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days.

If after treatment there is no improvement, or symptoms worsen, or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the route of administration and the doses indicated in the instructions for use.

Side effect:

Allergic reactions (rash, itching), burning are possible. Chlorhexidine in very rare cases (<0.0001%) can cause hypersensitivity reactions, including severe allergic reactions and anaphylaxis.

If any of the side effects indicated in the instructions are aggravated or any other side effects not indicated in the instructions are noted, you should immediately inform your doctor about it.

Overdose:

Overdose cases are unknown.

When using the drug in accordance with the instructions for use, an overdose is unlikely.

Interaction with other medicinal products:

As a precaution against possible interactions (antagonism or inactivation), it should not be used concomitantly with other antiseptics administered intravaginally.

DepantolЃ is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally.

Simultaneous use with iodine-containing preparations used intravaginally is not recommended.

If you are using the above or other drugs (including over-the-counter), consult your doctor before using DepantolЃ.

Special instructions:

If side effects occur, you should stop using the drug and consult a doctor.

During the treatment period, it is recommended to refrain from sexual intercourse.

Wash your hands before and after using the drug.

Influence on the ability to drive vehicles and work with mechanisms:

The use of the drug does not affect the ability to drive vehicles, work with mechanisms.

Release form:

Vaginal suppositories 100 mg 16 mg.

5 suppositories in a blister strip packaging made of polyvinyl chloride film laminated with polyethylene.

1 or 2 blister packs together with instructions for use of the medicinal product in a cardboard box.

Storage conditions:

At a temperature not higher than 25 ? C.

Keep out of the reach of children.

Shelf life:

2 years. Do not use after the expiration date printed on the package.

Vacation conditions:

Available without a prescription.

Manufacturer / organization accepting claims

JSC 'NIZHFARM', Russia

603950, Nizhny Novgorod,

GSP-459, st. Salganskaya, 7