Dehinel Plus Meat Flavored Tablets 10 Tablets

DESCRIPTION

Dehinel Plus - tablets for oral use for the treatment and prevention of helminthiasis in dogs. In appearance, the drug is a round yellow tablet with dark blotches, with beveled edges and a cross-shaped notch on one side.

COMPOSITION

The drug as active ingredients in 1 tablet contains: febantel - 150 mg, pyrantela embonate - 144 mg, praziquantel - 50 mg and auxiliary substances: lactose monohydrate, corn starch, povidone K30, sodium lauryl sulfate, microcrystalline cellulose, silicon colloidal stearate, , Aroma Meat Flavor 10022.

PHARMACOLOGICAL PROPERTIES

Dehinel Plus, thanks to its active ingredients, has antiparasitic activity against cestodes: Echinococcus granulosus, Echinococcus multilocularis, Mesocestoides lineatus, Diphyllobothrium latum, Dipylidium caninum, Multiceps multiceps, Taenia spp. and nematodes: Toxocara canis, Toxascaris leonina, Uncinaria spp., Ancylostoma spp., Trichuris vulpis. Febantel, moderately absorbed from the gastrointestinal tract, causes inhibition of tubulin protein synthesis and glucose intake in nematodes, while inhibiting fumarate reductase, an enzyme responsible for the energy metabolism of helminths.

Pirantel embonate is very poorly absorbed when administered orally and therefore exerts its effect directly on the surface of the mucous membrane of the gastrointestinal tract of a sick dog. It blocks neuromuscular impulse transmission in nematodes and causes paralysis of the helminth muscles, so the parasites are easily removed from the host's gastrointestinal tract.

Praziquantel is well absorbed in the gastrointestinal tract and has a detrimental effect on cestodes (tapeworms) by increasing the permeability of cell membranes of parasites for calcium ions and inhibition of fumarate reductase, which causes a spastic contraction of the parasite's muscles, turning into paralysis. Praziquantel is excreted unchanged in the bile.

Dehinel Plus, according to the degree of impact on the body of warm-blooded animals, belongs to low-hazard substances and does not have a sensitizing and hepatotoxic effect in recommended doses.

INDICATIONS

Dehinel Plus meat-flavored tablets are used for prophylactic and therapeutic purposes in dogs with nematodes (toxocariasis, toxascariasis, uicinariasis, hookworm disease, trichocephalosis) and cestodosis (teniidoses, dipylidiosis, echinococcosis, diphyllobothriasis, mesocytosis).

APPLICATION

Dehinel Plus meat-flavored tablets are administered to dogs individually orally once in the morning feeding at the rate of 1 tablet per 10 kg of animal weight. Doses of the drug depending on the weight of the animal are presented in the table:

Vis of an animal, kg Number of tablets

0.5-5 ? pills

6-10 1

11-15 1? pills

16-20 2

21-30 3

31-40 4 (or 1 tablet 2310mg)

41-50 5 (or 1? 2310mg tablet)

When deworming with Dehinel Plus meat-flavored tablets, a fasting diet and the use of laxatives are not required.

For therapeutic purposes, animals are deworming according to indications, for prophylactic purposes - on a quarterly basis in a therapeutic dose. In the case of intensive invasion, it is recommended to re-introduce the drug after 14 days at the same dose.

SPECIAL INSTRUCTIONS

The peculiarities of the action of the drug during its first use and its cancellation have not been established.

For pregnant and lactating females, Dehinel Plus meat-flavored tablets are used for health reasons under the supervision of the attending veterinarian.

It is not allowed to use the drug for puppies for the first two-thirds of the gestation period and for puppies under 3 weeks of age.

Violations of the recommended deworming times should be avoided, as this can lead to a decrease in effectiveness. If the next deworming is missed, the drug must be administered as soon as possible in the same dose, then the interval between drug injections does not change.

The drug is not intended for use in productive animals.

SIDE EFFECTS

As a rule, there are no side effects and complications when using Dehinela Plus with a taste of meat in accordance with this instruction. With increased individual sensitivity of the animal to the components of the drug and the appearance of allergic reactions, the use of its drug is discontinued and desensitizing therapy is carried out.

CONTRAINDICATIONS

Contraindication to use is the increased individual sensitivity of the animal to the components of the drug (including the history) and severe renal and liver dysfunction.

Depleted animals, sick with infectious diseases and weighing less than 0.5 kg, and puppies under 3 weeks of age are not subject to deworming.

SHELF LIFE AND STORAGE

Store the medicinal product in the manufacturer's packaging, separately from food and feed, in a place protected from direct sunlight, at a temperature of 0 В° C to 25 В° C, in places inaccessible to children.

The shelf life of the medicinal product, subject to storage conditions, is 3 years from the date of manufacture.

PACKAGING

The drug is packaged in blisters of 10 tablets, which are placed in cardboard boxes.

Specifications

KolVUP

ten

Manufacturer

KRKA

Temperature regime

from 0 to +30

Teaser

for the treatment and prevention of helminthiasis in dogs