Description

Dosage form

Cream is white or off-white.

Structure

1 g of cream contains

active substance: dexpanthenol 50 mg

excipients: propylene glycol 100 mg, methyl parahydroxybenzoate 0.8 mg, propyl parahydroxybenzoate 0.2 mg, macrogol cetostearate 16 mg, cetostearyl alcohol [cetyl alcohol not more than 60%, stearyl alcohol not less than 40%] 40 mg, liquid paraffin 80 mg, petroleum jelly 100 mg, sodium hydrogen phosphate dodecahydrate 0.2 mg, potassium dihydrogen phosphate 7.8 mg, purified water to 1 g.

general description

Tissue regeneration stimulant

Special conditions

For external use only.

Do not apply to wet wounds.

Influence on the ability to drive vehicles and mechanisms:

The drug does not affect the ability to drive vehicles or engage in other potentially hazardous activities requiring increased concentration of attention and speed of psychomotor reactions.

Drug interactions

Interactions with other drugs are unknown.

Pharmacodynamics

Dexpanthenol is a derivative of pantothenic acid.

Dexpanthenol is converted in the body into pantothenic acid, which is an integral part of coenzyme A and is involved in acetylation processes, in the synthesis of acetylcholine, corticosteroids, porphyrins.

In addition, it takes part in almost all metabolic processes (tricarboxylic acid cycle, metabolism of carbohydrates, fats and fatty acids, phospholipids, proteins, etc.), stimulates the regeneration of the skin, mucous membranes, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers.

It has a regenerating, metabolic and mild anti-inflammatory effect.

Pharmokinetics

When applied externally, it is rapidly absorbed by the skin and turns into pantothenic acid, binds to plasma proteins (mainly beta-globulin and albumin).

Its concentration in blood is 0.5-1 mg / l, in blood serum - 100 μg / l.

Pantothenic acid is not metabolized in the body (except for inclusion in Co-A), it is excreted unchanged.

Indications

In case of violation of the integrity of the skin: healing of burns (including sunburn), minor skin lesions (abrasions, cuts, cracks, etc.).

Prevention and treatment of dry skin, including as a consequence of dermatitis of various origins (manifested by peeling, redness, irritation, feeling of tightness), as well as daily care of skin areas that are most exposed to external factors (face, hands), including due to weathering.

For the care of the mammary gland during lactation (cracks and redness of the nipples of the mammary gland), for the care of infants and babies (diaper rash, diaper" dermatitis).

Contraindications

Hypersensitivity to drug components.

Pregnancy and lactation:

The drug can be used during pregnancy and during breastfeeding.

If the drug is used to treat cracked nipples during lactation, it should be washed off before breastfeeding.

Overdose

Overdose cases are unknown.

Side effects

Allergic reactions.

Allergic skin reactions (eg, contact dermatitis, allergic dermatitis, pruritus, redness, eczema, rash, hives, skin irritation).

If any of the side effects indicated in the instructions are aggravated, or any other side effects not indicated in the instructions are noted, you should immediately inform your doctor about it.

Structure

1 g of cream contains

active substance: dexpanthenol 50 mg

excipients: propylene glycol 100 mg, methyl parahydroxybenzoate 0.8 mg, propyl parahydroxybenzoate 0.2 mg, macrogol cetostearate 16 mg, cetostearyl alcohol [cetyl alcohol not more than 60%, stearyl alcohol not less than 40%] 40 mg, liquid paraffin 80 mg, petroleum jelly 100 mg, sodium hydrogen phosphate dodecahydrate 0.2 mg, potassium dihydrogen phosphate 7.8 mg, purified water to 1 g.

Specifications