Clotrimazolum | Clotrimazole-Akrikhin rr for external use 1% bottle 15 ml

Release form

Solution for external use.

Packing

Bottle 15 ml.

Pharmacological action

Clotrimazole - trichomonacid, antiprotozoal, antifungal, antibacterial.

Destroys the cytoplasmic membrane of microorganisms with the formation of vacuoles inside the cell, inhibits the synthesis of nucleic acids and proteins.

Pharmacodynamics

It has a wide range of fungicidal effects: effective against yeast (Candida albicans) and mold (phycomycetes) fungi, dermatophytes (including Trichophyton, Epidermophyton, Microsporum), Malassezia furfur includes an antibacterial spectrum. h Corynebacterium minutissima.

Pharmacokinetics

Poorly absorbed from the skin and mucous membranes. Accumulates in the stratum corneum of the epidermis.

Indications

- Fungal lesions of the skin and mucous membranes.

- Mycosis of the feet / hands, smooth skin of the trunk, limbs, folds, beard, mustache, scalp caused by dermatophytes.

- Pityriasis versicolor, spectra, candidiasis of the skin, genital mucosa, paronychia.

Contraindications

Hypersensitivity to clotrimazole, I trimester of pregnancy.

Use during pregnancy and lactation

In clinical and experimental studies, it was not found that the use of clotrimazole during pregnancy and lactation has a negative effect on the health of a woman or fetus (child). However, the question of the advisability of prescribing clotrimazole should be decided individually after consulting a doctor. In case of prescribing the drug to a pregnant woman, she should be warned that with the introduction of vaginal tablets, the applicator should not be used.

Composition of

1 ml of solution contains:

Active substance:

clotrimazole 10 mg

Excipients:

isopropyl myristinate,

ethanol anhydrous.

Dosage and Administration

Topically. For adults and children, a few drops of the solution are applied in a thin layer to the cleaned and dry affected and surrounding areas of the skin 2 times a day (morning and evening) and rubbed thoroughly. After eliminating the acute symptoms of the disease, treatment should be continued for up to 4 weeks, with dermatomycosis of the feet - within 2 weeks after the elimination of all symptoms.

Side effects

Rare: urticaria, swelling, rash, erythema, burning, itching, irritation at the site of application of the drug.

Drug Interaction

Reduces the effects of polyene antibiotics (amphotericin, nystatin, natamycin, etc.). Propyl ester of para-hydroxybenzoic acid in high concentrations enhances the antifungal action of clotrimazole, dexamethasone decreases.

Clotrimazole activity may be decreased when co-administered with nystatin.

Storage Conditions

In a dry, dark place at 15–25 РC.

Shelf life

3 years.

Active ingredient

Clotrimazole

Terms and conditions otpuska IZ drugstore

Without prescription

Possible product names

KLOTRIMAZOLE 1% 15ML PP-

KLOTRIMAZOL 1% 15ML. RR

Clotrimazole 1% rd d / nar. approx. 15ml Fl. B M

Clotrimazole RR 1% 15 ML

Clotrimazole rr 1% fl 15ml

Medan Farm, Poland