Clotrimazole | Clotrimazole vag, 6 tablets.

Latin name

Clotrimazole

release form

vaginal tablets

Packing

6 pcs

Pharmacological action

Clotrimazole - trichomonacid, antiprotozoal, antifungal, antibacterial.

Destroys the cytoplasmic membrane of microorganisms with the formation of vacuoles inside the cell, inhibits the synthesis of nucleic acids and proteins.

Pharmacodynamics

It has a wide range of fungicidal effects: effective against yeast (Candida albicans) and mold (phycomycetes) fungi, dermatophytes (including Trichophyton, Epidermophyton, Microsporum), Malassezia furfur includes an antibacterial spectrum. h Corynebacterium minutissima.

Pharmacokinetics

Poorly absorbed from the skin and mucous membranes. Accumulates in the stratum corneum of the epidermis.

Indications

Vulvovaginal candidiasis, Trichomonas vaginitis, with a preventive purpose before gynecological procedures.

Contraindications

Hypersensitivity to clotrimazole, I trimester of pregnancy.

Use during pregnancy and lactation

In clinical and experimental studies, it was not found that the use of clotrimazole during pregnancy and lactation has a negative effect on the health of a woman or fetus (child).

However, the question of the advisability of prescribing clotrimazole should be decided individually after consulting a doctor.

In case of prescribing the drug to a pregnant woman, she should be warned that the applicator should not be used with the introduction of vaginal tablets.

Composition

1 tablet contains:

Active ingredient:

clotrimazole 100 mg

Excipients:

lactose,

corn starch,

aerosil,

saric acid,

soda acid





Dosage and administration

Deep in the vagina, in the supine position, with slightly bent legs - 1 tablet 100 mg once a day (in the evening) for 6 days. A second course of treatment is possible after consulting a doctor.

For the rehabilitation of the birth canal, a single administration of one tablet is recommended.

Side effects

Lower gastrointestinal spasms, generalized erythema, rash, local allergic reactions (burning, itching).

Drug Interaction

Reduces the effects of polyene antibiotics (amphotericin, nystatin, natamycin, etc.).

Para-hydroxybenzoic acid propyl ester in high concentrations enhances the antifungal action of clotrimazole, dexamethasone decreases.

Clotrimazole activity may be decreased when co-administered with nystatin.

Storage Conditions

In a dry, dark place at 15–25 РC.

Shelf life

3 years

Deystvuyushtee substance

Clotrimazole

dosage form

vaginal tablets

Appointment

Appointment

Pregnant women II and III trimester as prescribed by the doctor, Adults, Nursing mothers, For women

GlaxoSmithKline, UK