Clotrimazole | Candide external solution 1%, 20 ml

Latin name

Candid

Release form

Solution for local use

Packing

Bottle of 20 ml

Pharmacological action

Candide is a broad-spectrum antifungal.

The antimycotic effect of the active substance, clotrimazole (an imidazole derivative), is associated with impaired synthesis of ergosterol, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.

It acts fungistatically in small concentrations, fungicidal in large concentrations, and not only on proliferating cells.

In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in the concentration of hydrogen peroxide to a toxic level, which also contributes to the destruction of fungal cells.

Effective against dermatophytes, yeast-like and mold fungi, as well as the causative agent of colorful lichen (Pityriasis versicolor) and the pathogen of erythrasma.

It has antimicrobial activity against gram-positive (staphylococci, streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

Indications

dermatophytosis of the head (including the face), body, legs

mycosis of nails

multicolor lichen

skin candidiasis

candida paronychia

candidal vulvitis

candidal senate pulmonary fungal inflammation erythrasma.

Contraindications

specific skin lesions (including tuberculosis, chickenpox, herpes simplex, measles, syphilis)

skin reactions at the site of vaccination

hypersensitivity to the components of the drug.

Use during pregnancy and lactation

The safety of the drug Candide during pregnancy and lactation has not been established.

Therefore, the administration of the drug in large quantities or for a long time during these periods should be avoided.



Composition 1 ml solution contains:

Active substance:

clotrimazole

10 mg Excipients:

propylene glycol - 495 mg

glycerin - 495 mg.

Dosage and Administration

Externally.

Apply the solution to previously washed (using soap with a neutral pH value) and dried affected skin areas 2 times a day.

The duration of treatment depends on the severity of the disease, the localization of pathological changes and the effectiveness of therapy.

Treatment of dermatomycosis is carried out for at least 4 weeks, pityriasis versicolor - 1-3 weeks.

For fungal diseases of the skin of the legs, it is recommended that therapy be continued for at least 2 weeks after the symptoms of the disease have been resolved.

Side effects of

Itching, burning and swelling of the vaginal mucosa, vaginal discharge, headache, gastralgia, frequent urination, intercurrent cystitis, burning sensation in the penis act.

overdose

Using the drug at high doses does not cause any life-threatening reactions and conditions.

Symptoms (in case of unintended use of the drug inside): anorexia, nausea, vomiting, gastralgia, liver dysfunction rarely - drowsiness, hallucinations, pollakuria, skin allergic reactions.

Treatment: Activation of activated charcoal, if necessary - no symptomatic therapy for a specific antidote.

Storage Conditions

The product should be stored in a dry, dark place at a temperature not exceeding 25 РC.

Shelf life

3 years

Active substance

Clotrimazole

Dosage form

for external use

Possible product names

CANDID 1% 20ML R-R

CANDID 1% 20ML FLAC R-R D / OUTDOOR

20 CAND. RR D / NAR. NOTE

Candide 1% solution for external approx. 20ml Fl. X1

Candide solution 1% fl. 20ml